A group from National Agriculture and Food Research Organization, Tsu, Japan, etc. has reported on biocontrol activity of nonpathogenic Fusarium oxysporum strains against pathogenic Fusarium wild type strains.
The idea of using nonpathogenic F. oxysporum to control Fusarium diseases came from studies of soils naturally suppressive to Fusarium wilt disease.
In this report, the following strains were used to demonstrate biocontrol activities of nonpathogenic mutants of F. oxysporum against pathogenic fusarium wild types.
Pathogenic Fusarium wild type strains: F. oxysporum f. sp. melonis strain Mel020120, and F. oxysporum f. sp. lycopersici strain CK3-1
Nonpathogenic Fusarium strains: F. oxysporum strain MFG6, ΔFOW2 Mel02010 MF2-1, and ΔFOW2 CK3-1 LF2-1
Pre-inoculation of roots with the nonpathogenic strains are quite effective. Actually, it was shown separately that conidial germination and hyphal elongation of the pathogenic fusarium wild-type strain were markedly inhibited on the root surface pre-inoculated with the nonpathogenic strains.