A group from Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK has reported that FUT-8 could be a a druggable target for prostate cancer therapy.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12086987/
It has been shown that FUT8 as an important driver of prostate cancer progression and points to the need for further characterization of core fucosylation in prostate tumours.
Given the critical roles of FUT8 in prostate cancer biology, it is poised to be a druggable target for cancer therapy.