From the laboratory tests of 1850 hospitalized COVID-19 patients in Wuhan, the following group discussed the dynamic changes in IgG to SARS-CoV-2. If the IgG level is low, the complete elimination of the virus becomes difficult, and thereby there is a chance that RT-PCR SARS-CoV-2 virus testing after recovery (i.e., after discharge) becomes positive.
https://www.nature.com/articles/s41467-020-19943-y
Dynamic changes in IgG include:
- In severe cases, IgG level tends to be delayed by nearly a week compared to those with mild cases.
- In severe cases, the level of IgG is significantly higher, and even in the elderly, the level of IgG tends to be higher.
- It should be noted that patients with low levels of IgG at the time of hospital discharge may positive with RT-PCR reteaching of SARS-CoV-2.