A group from Northwest University, Xi’an, China, etc. has reported a potential glycan biomarker for Esophageal squamous cell carcinoma (ESCC)
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https://www.frontiersin.org/articles/10.3389/fchem.2021.637730/full
Saliva was used as a sample in this study, and saliva was centrifuged to remove insoluble components and a protease inhibitor was added. Lectin microarrays using 37 lectins were used for investigating differences in glycosylation patterns between healthy volunteers (HV) and ESCC patients. As a result, it was found that DSA and ECA lectins are specific to ESCC, and Galβ1-4GlcNAc-containing N-glycans could be potential biomarkers for ESCC.
