A group of Harvard Medical Schools has reported potential biomarkers for pancreatic duct adenocarcinoma using pancreatic duct adenocarcinoma derived organoids.
https://insight.jci.org/articles/view/135544
(1) From the viewpoint of glycans: High mannose and Lewis X epitope structures increase in pancreatic duct adenocarcinoma.
(2) From the viewpoint of extracellular vesicles (EV) proteins: ANXA11 (anexine A11: calcium-dependent phospholipid binding protein mobilized in the budding region of the transport endoplasmic reticulum COPII of the endoplasmic reticulum) is increased.
Let’s look forward to further research progress.