A group from The First Affiliated Hospital of Anhui Medical University, Hefei, China, etc. has reported serum glycan biomarkers for Intracerebral hemorrhage (ICH).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105815/
The area under curve (AUC) were yielded as
0.93 for ConA (P<0.01),
0.95 for PNA (P<0.01),
0.67 for VVA (P=0.04),
0.92 for AAL (P<0.01),
0.86 for LTL (P<0.01),
0.84 for AIL (P<0.01).
The sensitivity/specificity were as follows,
75.0%/95.8% for ConA,
100.0%/64.7% for PNA,
75.0%/58.3% for VVA,
100.0%/72.9% for AAL,
87.5%/79.2% for LTL,
A68.8%/83.3% for AIL.
As a result, α-Man/α-Glc (ConA) exhibited the best specificity. It is worthy to note that α-Man/α-Glc may be a potential biomarker with diagnostic and prognostic value in ICH and ConA will be a good probe for that.