Gal modification of laminin receptor integrin α6β1 is reduced in hepatocellular carcinoma, and thereby accelerates cancer cell invasion

Gal modification of laminin receptor integrin α6β1 is reduced in hepatocellular carcinoma, and thereby accelerates cancer cell invasion

A group from Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan, etc. has reported that Beta1,4-galactosyltransferases (B4GALTs) downregulation upregurates agalacto N-glycans and enhances the laminin-binding activity of integrin α6 and integrin β1 to promote invasiveness of Hepatocellular carcinoma (HCC) cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618527/

Mx

Pioneer in Glycan Profiling Technology Environmentally Regenerative Agriculture

Comments are closed.

Powered by WordPress |Copyright © 2020 Emukk. All rights reserved