A group from Institute of Chemistry, Slovak Academy of Sciences, SK-84538 Bratislava, Slovakia, etc. has reported about alterations in the Glycan modification of Serum Glycoproteins in Attention-Deficit Hyperactivity Disorder (ADHD).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218324/
This study is focusing on determining whether serum glycan analysis holds the potential to identify novel ADHD biomarkers based on changes in glycosylation. They applied combined glycan analysis using two different techniques, lectin microarray and MALDI-TOF MS methods.
As a result, it was found that antennary fucosylation increases, di-/triantennary N-glycans with bisecting GlcNAc and α2-3 sialylation decrease in ADHD.