{"id":9905,"date":"2022-09-19T07:24:21","date_gmt":"2022-09-18T22:24:21","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=9905"},"modified":"2022-09-19T07:24:21","modified_gmt":"2022-09-18T22:24:21","slug":"%e5%89%8d%e7%ab%8b%e8%85%ba%e3%81%8c%e3%82%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8bpsma%e3%81%ae%e7%89%b9%e7%95%b0%e7%9a%84%e3%81%aa%e7%b3%96%e9%8e%96%e4%bf%ae%e9%a3%be","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e5%89%8d%e7%ab%8b%e8%85%ba%e3%81%8c%e3%82%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8bpsma%e3%81%ae%e7%89%b9%e7%95%b0%e7%9a%84%e3%81%aa%e7%b3%96%e9%8e%96%e4%bf%ae%e9%a3%be\/","title":{"rendered":"\u524d\u7acb\u817a\u304c\u3093\u306b\u304a\u3051\u308bPSMA\u306e\u7279\u7570\u7684\u306a\u7cd6\u9396\u4fee\u98fe"},"content":{"rendered":"

Leroy T. Canoles Jr. Cancer Research Center, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u8ee2\u79fb\u6027\u524d\u7acb\u817a\u304c\u3093\u306e\u524d\u7acb\u817a\u7279\u7570\u7684\u819c\u6297\u539f\uff08PSMA\uff09\u306eN-\u578b\u7cd6\u9396\u4fee\u98fe\u4f4d\u7f6e\u6bce\u306e\u7cd6\u9396\u4fee\u98fe\u306e\u9055\u3044\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9435049\/<\/a><\/p>\n

\u8449\u9178\u52a0\u6c34\u5206\u89e3\u9175\u7d20 1 (FOLH1) \u307e\u305f\u306f\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u30ab\u30eb\u30dc\u30ad\u30b7\u30da\u30d7\u30c1\u30c0\u30fc\u30bc 2 \u3068\u3057\u3066\u3082\u77e5\u3089\u308c\u308b\u524d\u7acb\u817a\u7279\u7570\u7684\u819c\u6297\u539f (PSMA) \u306f\u3001\u5f93\u6765\u306e\u751f\u5316\u5b66\u7684\u65b9\u6cd5\u3092\u4f7f\u7528\u3057\u3066\u7d44\u7e54\u304a\u3088\u3073\u4f53\u6db2\u4e2d\u306e\u524d\u7acb\u817a\u304c\u3093\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u4ee5\u524d\u3088\u308a\u7814\u7a76\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u7d50\u679c\u306f\u3070\u3089\u3064\u3044\u3066\u3044\u307e\u3057\u305f\u3002\u3053\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u524d\u7acb\u817a\u4e0a\u76ae\u3001\u56fa\u5f62\u816b\u760d\u306e\u65b0\u8840\u7ba1\u7cfb\u5168\u822c\u3001\u304a\u3088\u3073\u814e\u8fd1\u4f4d\u5c3f\u7d30\u7ba1\u3001\u5341\u4e8c\u6307\u8178\u3001\u304a\u3088\u3073\u795e\u7d4c\u7cfb\u306e\u795e\u7d4c\u7bc0\u3092\u542b\u3080\u3044\u304f\u3064\u304b\u306e\u5065\u5eb7\u306a\u7d44\u7e54\u3067\u306f\u3001\u5c11\u91cf\u306e\u767a\u73fe\u306b\u3068\u3069\u307e\u308a\u307e\u3059\u304c\u3001\u524d\u7acb\u817a\u304c\u3093\u3067\u306f\u3001PSMA \u306e\u5b58\u5728\u91cf\u306f\u75be\u60a3\u306e\u91cd\u75c7\u5ea6\u3068\u3068\u3082\u306b\u5897\u52a0\u3057\u3001\u6b63\u5e38\u7d44\u7e54\u3068\u6bd4\u8f03\u3057\u3066\u3001\u75be\u60a3\u306e\u9032\u884c\u3057\u305f\u8ee2\u79fb\u6027\u306e\u305d\u308c\u3067\u306f\u3001\u6700\u5927100 \u500d\u9ad8\u3044\u5b58\u5728\u91cf\u304c\u89b3\u5bdf\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u672c\u7814\u7a76\u306b\u304a\u3044\u3066\u306f\u3001\u3075\u305f\u3064\u306e\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de\u682a\u3001LNCaP \u7d30\u80de\u3001(CRL-1740) \u304a\u3088\u3073 MDAPCa2b (ATCC CRL-2422) \u3092\u4f7f\u7528\u3057\u3066\u3001PSMA \u306eN-\u578b\u7cd6\u9396\u4fee\u98fe\u4f4d\u7f6e\u6bce\u306e\u7279\u7570\u7684\u7cd6\u9396\u4fee\u98fe\u69cb\u9020\u306e\u7279\u5fb4\u4ed8\u3051\u304c\u6bd4\u8f03\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7570\u306a\u308b\u8868\u73fe\u578b\u3092\u6301\u3064\u3075\u305f\u3064\u306e\u7d30\u80de\u682a LNCaP \u3068 MDAPCa2b \u3067\u306f\u3001\u5e7e\u3064\u304b\u306e\u7cd6\u9396\u4fee\u98fe\u306e\u767a\u73fe\u306b\u6709\u610f\u5dee\u304c\u3042\u308a\uff08\u4e0b\u56f3\u53c2\u7167\uff09\u3001\u66f4\u306b\u306f\u3001LNCaP \u7d30\u80de\u3068\u6bd4\u8f03\u3057\u3066 MDAPCa2b \u3067\u8b58\u5225\u3055\u308c\u308b\u7cd6\u9396\u4fee\u98fe\u304c\u6709\u610f\u306b\u9ad8\u3044\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002
\n\u3053\u308c\u3089\u306e\u60c5\u5831\u306f\u3001\u5c06\u6765\u7684\u306b\u524d\u7acb\u817a\u304c\u3093\u306e\u9032\u884c\u5ea6\u3092\u628a\u63e1\u3059\u308b\u70ba\u306ePSMA\u306eN-\u578b\u7cd6\u9396\u4fee\u98fe\u4f4d\u7f6e\u6bce\u306e\u7279\u7570\u7684\u7cd6\u9396\u4fee\u98fe\u3092\u7528\u3044\u305f\u4e88\u5f8c\u30de\u30fc\u30ab\u30fc\u958b\u767a\u306e\u57fa\u790e\u306b\u306a\u308b\u3084\u3082\u77e5\u308c\u307e\u305b\u3093\u3002<\/p>\n

\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Leroy T. Canoles Jr. Cancer Research Center, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA\u3089\u306e\u30b0\u30eb<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642,42],"tags":[],"class_list":["post-9905","post","type-post","status-publish","format-standard","hentry","category-nature-ja","category-technology-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9905","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=9905"}],"version-history":[{"count":5,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9905\/revisions"}],"predecessor-version":[{"id":9913,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9905\/revisions\/9913"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=9905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=9905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=9905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}