{"id":9722,"date":"2022-08-22T07:05:31","date_gmt":"2022-08-21T22:05:31","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=9722"},"modified":"2022-08-22T07:09:05","modified_gmt":"2022-08-21T22:09:05","slug":"comparison-of-spr-detection-of-sars-cov-2-spike-protein-with-using-gold-nanorods-aunrs-and-gold-nanoparticles-aunps","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/comparison-of-spr-detection-of-sars-cov-2-spike-protein-with-using-gold-nanorods-aunrs-and-gold-nanoparticles-aunps\/","title":{"rendered":"Comparison of SPR detection of SARS-CoV-2 spike protein with using gold nanorods (AuNRs) and gold nanoparticles (AuNPs)"},"content":{"rendered":"<p>A group from Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, U.K., etc. has reported about comparison of SPR detection of SARS-CoV-2 spike protein with using gold nanorods (AuNRs) and gold nanoparticles (AuNPs).<br \/>\n<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsmacrolett.1c00716\">https:\/\/pubs.acs.org\/doi\/10.1021\/acsmacrolett.1c00716<\/a><\/p>\n<p>2,3-sialyllactose was immobilized onto AuNPs and AuNRs to detect SARS-CoV-2 with using a SPR detection method.<\/p>\n<p>To highlight the importance of anisotropic particles (e.g., nanorods), spherical AuNRs were compared with AuNPs.<br \/>\n(1)AuNPs (40nm) showed the maximum aborbance at \u223c520 nm, and AuNRs (10 \u00d7 38 nm) showed the maximum absorbance at ~780 nm.<br \/>\n(2)Although AuNPs (which generates a signal due to aggregation) did not show significant spectral changes with this spike protein, AuNRs showed spectral change with increasing concentration of spike protein.<br \/>\n(3)The signal output from AuNRs using the primary clinical samples was correlated with the Ct (cycle threshold) values from RT-PCR.<\/p>\n<p>Thus, it has clearly shown that AuNRs are better than AuNPs.<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-9718\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2-300x130.png\" alt=\"\" width=\"300\" height=\"130\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2-300x130.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2-600x261.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2-768x334.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2-920x400.png 920w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2-230x100.png 230w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2-350x152.png 350w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2-480x209.png 480w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/AuNRs-vs-AuNPs_SARS-CoV-2.png 1023w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, U.K., etc. has report<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/comparison-of-spr-detection-of-sars-cov-2-spike-protein-with-using-gold-nanorods-aunrs-and-gold-nanoparticles-aunps\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-9722","post","type-post","status-publish","format-standard","hentry","category-technology-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9722","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=9722"}],"version-history":[{"count":1,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9722\/revisions"}],"predecessor-version":[{"id":9723,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9722\/revisions\/9723"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=9722"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=9722"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=9722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}