{"id":9614,"date":"2022-08-13T08:02:03","date_gmt":"2022-08-12T23:02:03","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=9614"},"modified":"2022-08-13T08:14:36","modified_gmt":"2022-08-12T23:14:36","slug":"bisecting-glcnac%e3%81%ab%e6%9c%80%e3%82%82%e7%89%b9%e7%95%b0%e7%9a%84%e3%81%aa%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/bisecting-glcnac%e3%81%ab%e6%9c%80%e3%82%82%e7%89%b9%e7%95%b0%e7%9a%84%e3%81%aa%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3\/","title":{"rendered":"Bisecting GlcNAc\u306b\u6700\u3082\u7279\u7570\u7684\u306a\u30ec\u30af\u30c1\u30f3"},"content":{"rendered":"<p>Department of Chemistry, Georgia State University, Atlanta GA USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001bisecting GlcNAc\u306b\u7279\u7570\u7684\u306a\u30ec\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9241959\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9241959\/<\/a><\/p>\n<p>\u591a\u304f\u306e\u690d\u7269\u30ec\u30af\u30c1\u30f3\u306fbisecting GlcNAc \u304c\u3042\u3063\u3066\u3082\u591a\u304f\u306e\u5f71\u97ff\u306f\u53d7\u3051\u307e\u305b\u3093\u304c\u3001\u305d\u306e\u4e2d\u3067 PHA-E \u3068 Calsepa \u306e\u7d50\u5408\u306f\u3001bisecting GlcNAc\u306e\u5b58\u5728\u306b\u3088\u3063\u3066\u5f37\u5316\u3055\u308c\u307e\u3057\u305f\u3002\u4f4e\u6fc3\u5ea6 (1 \u03bcg\/mL) \u3067\u3042\u3063\u3066\u3082\u3001PHA-E \u3068 Calsepa \u306fbisecting GlcNAc\u306e\u7121\u3044\u4e8c\u5206\u5c90N-\u578b\u7cd6\u9396\u3078\u306e\u7d50\u5408\u3092\u793a\u3057\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u3001bisecting GlcNAc\u306e\u540c\u5b9a\u3068\u764c\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u767a\u898b\u3068\u3044\u3063\u305f\u5e45\u5e83\u3044\u30a2\u30d7\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3\u306b\u304a\u3044\u3066\u554f\u984c\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u9a5a\u304f\u3079\u304d\u3053\u3068\u306b\u3001PHA-L \u306fbisecting GlcNAc\u3078\u306e\u7279\u7570\u7684\u8a8d\u8b58\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u4f8b\u3048\u3070\u3001\u03b21-6 \u5206\u5c90\u578b\u7cd6\u9396\u304c\u5b58\u5728\u3057\u306a\u3044\u6297\u4f53\u306a\u3069\u306e\u69cb\u9020\u3092\u30d7\u30ed\u30fc\u30d6\u3059\u308b\u969b\u306b\u6709\u671b\u306a\u30ec\u30af\u30c1\u30f3\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u3057\u304b\u3057\u3001PHA-L\u306f\u3001\u591a\u5206\u5c90\u306eN-\u578b\u7cd6\u9396\u306b\u5f37\u3044\u7279\u7570\u6027\u3092\u6301\u3063\u3066\u3044\u308b\u3053\u3068\u306b\u306f\u6ce8\u610f\u3057\u3066\u304a\u3044\u305f\u65b9\u304c\u826f\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-9615\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP-300x182.png\" alt=\"\" width=\"300\" height=\"182\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP-300x182.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP-600x364.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP-768x466.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP-230x140.png 230w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP-350x213.png 350w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP-480x292.png 480w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/08\/bisectingGlcNAc-and-GBP.png 815w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Department of Chemistry, Georgia State University, Atlanta GA USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001bisecting GlcNAc\u306b\u7279\u7570\u7684\u306a\u30ec\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/bisecting-glcnac%e3%81%ab%e6%9c%80%e3%82%82%e7%89%b9%e7%95%b0%e7%9a%84%e3%81%aa%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-9614","post","type-post","status-publish","format-standard","hentry","category-technology-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9614","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=9614"}],"version-history":[{"count":5,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9614\/revisions"}],"predecessor-version":[{"id":9622,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/9614\/revisions\/9622"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=9614"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=9614"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=9614"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}