{"id":8896,"date":"2022-06-02T06:00:44","date_gmt":"2022-06-01T21:00:44","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=8896"},"modified":"2022-06-02T06:21:41","modified_gmt":"2022-06-01T21:21:41","slug":"%e3%83%91%e3%83%ab%e3%83%9f%e3%83%88%e3%82%a4%e3%83%ab%e3%82%a8%e3%82%bf%e3%83%8e%e3%83%bc%e3%83%ab%e3%82%a2%e3%83%9f%e3%83%89%ef%bc%88pea%ef%bc%89%e3%81%8ccovid-19%e3%81%ae%e5%84%aa%e3%82%8c%e3%81%9f","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e3%83%91%e3%83%ab%e3%83%9f%e3%83%88%e3%82%a4%e3%83%ab%e3%82%a8%e3%82%bf%e3%83%8e%e3%83%bc%e3%83%ab%e3%82%a2%e3%83%9f%e3%83%89%ef%bc%88pea%ef%bc%89%e3%81%8ccovid-19%e3%81%ae%e5%84%aa%e3%82%8c%e3%81%9f\/","title":{"rendered":"\u30d1\u30eb\u30df\u30c8\u30a4\u30eb\u30a8\u30bf\u30ce\u30fc\u30eb\u30a2\u30df\u30c9\uff08PEA\uff09\u304cCOVID-19\u306e\u512a\u308c\u305f\u88dc\u52a9\u7642\u6cd5\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b"},"content":{"rendered":"<p>Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56100 Pisa, Italy\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30d1\u30eb\u30df\u30c8\u30a4\u30eb\u30a8\u30bf\u30ce\u30fc\u30eb\u30a2\u30df\u30c9\uff08PEA\uff09\u306f\u3001COVID-19\u306e\u73fe\u5728\u306e\u6cbb\u7642\u6cd5\u3001\u66f4\u306b\u306f\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3068\u540c\u69d8\u306a\u611f\u67d3\u5897\u6b96\u7d4c\u8def\u3092\u6301\u3064\u65b0\u898f\u306eRNA\u30a6\u30a4\u30eb\u30b9\u306b\u5bfe\u3059\u308b\u6709\u671b\u306a\u88dc\u52a9\u7642\u6cd5\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35632821\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35632821\/<\/a><\/p>\n<p>SARS-CoV-2\u306b\u5bfe\u3059\u308b\u963b\u5bb3\u5206\u5b50\u306e\u5019\u88dc\u306e1\u3064\u306b\u3001N-\u30a2\u30b7\u30eb\u30a8\u30bf\u30ce\u30fc\u30eb\u30a2\u30df\u30f3\u30d5\u30a1\u30df\u30ea\u30fc\u306e\u30e1\u30f3\u30d0\u30fc\u306e1\u3064\u3067\u3042\u308bPEA\u304c\u3042\u308a\u307e\u3059\u3002PEA\u306f\u3001\u672b\u68a2\u708e\u75c7\u304a\u3088\u3073\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u3092\u963b\u5bb3\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u30e9\u30c3\u30c8\u304a\u3088\u3073\u30de\u30a6\u30b9\u306b\u304a\u3044\u3066\u795e\u7d4c\u4fdd\u8b77\u304a\u3088\u3073\u6297\u4fb5\u5bb3\u53d7\u5bb9\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u6700\u8fd1\u3001\u3053\u306ePEA\u306e\u6297\u708e\u75c7\u4f5c\u7528\u304c\u30a2\u30ca\u30f3\u30c0\u30df\u30c9\u3068\u540c\u3058\u7d4c\u8def\u3092\u305f\u3069\u3089\u306a\u3044\u3053\u3068\u304c\u767a\u898b\u3055\u308c\u307e\u3057\u305f\u3002PEA\u8a98\u767a\u6027\u306e\u93ae\u75db\u304a\u3088\u3073\u6297\u708e\u75c7\u6d3b\u6027\u306f\u3001\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5897\u6b96\u56e0\u5b50\u53d7\u5bb9\u4f53\u30a2\u30eb\u30d5\u30a1\uff08PPAR-\u03b1\uff09\u306e\u6d3b\u6027\u5316\u306b\u3088\u3063\u3066\u5a92\u4ecb\u3055\u308c\u3001PPAR-\u03b1\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u304a\u3088\u3073\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5185\u306e\u30d9\u30fc\u30bf\u9178\u5316\u306e\u6d3b\u6027\u5316\u3001\u304a\u3088\u3073\u30df\u30af\u30ed\u30bd\u30fc\u30e0\u5185\u306e\u30aa\u30e1\u30ac\u9178\u5316\u306e\u540c\u6642\u523a\u6fc0\u306b\u3088\u308b\u8102\u80aa\u6ef4\u306e\u7834\u58ca\u306b\u3064\u306a\u304c\u308b\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30ab\u30b9\u30b1\u30fc\u30c9\u3092\u767a\u52d5\u3057\u307e\u3059\u3002\u7d30\u83cc\u304a\u3088\u3073\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306e\u4e88\u9632\u307e\u305f\u306f\u6cbb\u7642\u306b\u5bfe\u3057\u3066\u3001PEA\u306e\u6709\u52b9\u6027\u3082\u6563\u898b\u3055\u308c\u308b\u3053\u3068\u304b\u3089\u3001\u672c\u7814\u7a76\u306b\u304a\u3044\u3066\u306f\u3001PEA\u304cSARS-CoV-2\u306e\u611f\u67d3\u5897\u6b96\u3092\u963b\u5bb3\u3059\u308b\u305f\u3081\u306b\u4f7f\u7528\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u306b\u3064\u3044\u3066\u691c\u8a0e\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>PEA\u306e\u7d30\u80de\u6bd2\u6027\u3067\u3059\u304c\u3001PEA\u304cHuh-7\u304a\u3088\u3073293T\u7d30\u80de\u306b100\u03bcM\u3082\u306e\u9ad8\u6fc3\u5ea6\u3067\u30a2\u30d7\u30e9\u30a4\u3055\u308c\u305f\u5834\u5408\u3067\u3082\u3001\u305d\u306e\u6bd2\u6027\u306f\u691c\u51fa\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002Huh7\u7d30\u80de\u3092\u7528\u3044\u305fSARS-CoV-2\u306e\u611f\u67d3\u5b9f\u9a13\u306b\u304a\u3044\u3066\u30011\u03bcM\u306e\u6fc3\u5ea6\u306ePEA\u3092SARS-CoV-2\u3068\u540c\u6642\u306b\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30c8\u3057\u305f\u5834\u5408\u306b\u306f\u3001\u611f\u67d372\u6642\u9593\u5f8c\u306eqRT-PCR\u3067\u6e2c\u5b9a\u306b\u3066\u3001SARS-CoV-2\u30b2\u30ce\u30e0\u306e\u91cf\u306f\u7d0464\uff05\u6e1b\u5c11\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p><a><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-8902\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/06\/PEA_SARS-CoV-2_infection-300x187.png\" alt=\"\" width=\"300\" height=\"187\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/06\/PEA_SARS-CoV-2_infection-300x187.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/06\/PEA_SARS-CoV-2_infection-600x373.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/06\/PEA_SARS-CoV-2_infection-768x478.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/06\/PEA_SARS-CoV-2_infection.png 788w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>PEA\u306e\u52b9\u679c\u304c\u3001SARS-CoV-2\u306e2\u3064\u306e\u4e3b\u8981\u306a\u5909\u7570\u682a\uff08\u30c7\u30eb\u30bf\u304a\u3088\u3073\u30aa\u30df\u30af\u30ed\u30f3\uff09\u306b\u5bfe\u3057\u3066\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u300210\u304a\u3088\u30731\u03bcM\u306ePEA\u524d\u51e6\u7406Huh-7\u7d30\u80de\u3067\u306f\u3001\u30c7\u30eb\u30bf\u5909\u7570\u682a\u306e\u30a6\u30a4\u30eb\u30b9\u30b2\u30ce\u30e0\u306e\u6570\u304c62.4\uff05\u304a\u3088\u307351.2\uff05\u3001\u30aa\u30df\u30af\u30ed\u30f3\u5909\u7570\u682a\u3067\u306f\u300143.4\uff05\u304a\u3088\u307377.3\uff05\u6e1b\u5c11\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001PEA\u306b\u66dd\u9732\u3055\u308c\u305fSARS-CoV-2\u30c7\u30eb\u30bf\u304a\u3088\u3073\u30aa\u30df\u30af\u30ed\u30f3\u5909\u7570\u682a\u306b\u304a\u3044\u3066\u306f\u300110\u03bcM PEA\u3067\u3001\u30a6\u30a4\u30eb\u30b9\u30b2\u30ce\u30e0\u304c\u6700\u592765\uff05\u8fd1\u304f\u306e\u6e1b\u5c11\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001PEA\u3092\u7d30\u80de\u3068\u30a6\u30a4\u30eb\u30b9\u306e\u4e21\u65b9\u306b\u540c\u6642\u306b\u30a2\u30d7\u30e9\u30a4\u3057\u305f\u5834\u5408\u3067\u306f\u30011\u03bcM\u3067\u6295\u4e0e\u3055\u308c\u305fPEA\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u30b2\u30ce\u30e0\u304c\u5927\u5e45\u306b\u6e1b\u5c11\u3057\u3001\u30c7\u30eb\u30bf\u304a\u3088\u3073\u30aa\u30df\u30af\u30ed\u30f3\u5909\u7570\u682a\u3067\u3001\u305d\u308c\u305e\u308c75.3\uff05\u304a\u3088\u307372.5\uff05\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, Universi<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e3%83%91%e3%83%ab%e3%83%9f%e3%83%88%e3%82%a4%e3%83%ab%e3%82%a8%e3%82%bf%e3%83%8e%e3%83%bc%e3%83%ab%e3%82%a2%e3%83%9f%e3%83%89%ef%bc%88pea%ef%bc%89%e3%81%8ccovid-19%e3%81%ae%e5%84%aa%e3%82%8c%e3%81%9f\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-8896","post","type-post","status-publish","format-standard","hentry","category-technology-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Retrovirus Center, Department of Translational Research\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" 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