{"id":8813,"date":"2022-05-16T10:07:13","date_gmt":"2022-05-16T01:07:13","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=8813"},"modified":"2022-05-16T10:10:46","modified_gmt":"2022-05-16T01:10:46","slug":"the-importance-of-booster-vaccine-doses-for-protection-against-all-omicron-variants","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/the-importance-of-booster-vaccine-doses-for-protection-against-all-omicron-variants\/","title":{"rendered":"The importance of booster vaccine doses for protection against all Omicron variants"},"content":{"rendered":"<p>A group from Center for Retrovirus Research, The Ohio State University, Columbus, OH 43210, USA, etc. has reported about the importance of booster vaccine doses for protection against all Omicron variants.<br \/>\n<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1931312822002207?via%3Dihub\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1931312822002207?via%3Dihub<\/a><\/p>\n<p>There are several Omicron sub-lineages with significant variations in their S proteins, including BA.1, BA.1.1, and BA.2. While the constellation of mutations varies between isolates, the BA.1.1 lineage is defined by the presence of a single R346K mutation that is absent from the BA.1 lineage, whereas the BA.2 lineage is defined by key S mutations T19I, L24S, \u039425\/27, V213G, T376A, and R408S. Although BA.1 was the major variant during the Omicron wave of the pandemic, the BA.2 variant, and to a lesser extent BA.1.1, has begun to account for an increasing proportion of cases. In particular, the BA.2 variant exhibits enhanced transmissibility relative to BA.1 and can reinfect previously BA.1-infected individuals. <\/p>\n<p>In this study, authors have demonstrated the followings:<br \/>\nOmicron BA.1.1 is effectively neutralized by Omicron patient sera, and Omicron sub-lineages are comparably neutralized by Omicron patient sera.<br \/>\nOmicron BA.1 and BA.2 are resistant to neutralization by two-dose mRNA vaccination but sensitive to neutralization after a booster dose.<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/05\/Omicron-NT50s.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/05\/Omicron-NT50s-300x88.png\" alt=\"\" width=\"300\" height=\"88\" class=\"alignnone size-medium wp-image-8809\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/05\/Omicron-NT50s-300x88.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/05\/Omicron-NT50s-600x177.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/05\/Omicron-NT50s-768x226.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/05\/Omicron-NT50s.png 953w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from Center for Retrovirus Research, The Ohio State University, Columbus, OH 43210, USA, etc. has repo<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/the-importance-of-booster-vaccine-doses-for-protection-against-all-omicron-variants\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-8813","post","type-post","status-publish","format-standard","hentry","category-technology-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/8813","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=8813"}],"version-history":[{"count":3,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/8813\/revisions"}],"predecessor-version":[{"id":8817,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/8813\/revisions\/8817"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=8813"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=8813"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=8813"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}