{"id":8480,"date":"2022-04-09T06:55:13","date_gmt":"2022-04-08T21:55:13","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=8480"},"modified":"2022-04-09T06:55:13","modified_gmt":"2022-04-08T21:55:13","slug":"sars-cov-2%e3%81%af%e3%80%81%e6%84%9f%e6%9f%93%e5%88%9d%e6%9c%9f%e9%81%8e%e7%a8%8b%e3%81%a7%e7%b4%b0%e8%83%9e%e8%86%9c%e4%b8%8a%e3%81%ae%ce%b1-26-sialic-acids%e3%81%ab%e7%b5%90%e5%90%88%e3%81%99","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/sars-cov-2%e3%81%af%e3%80%81%e6%84%9f%e6%9f%93%e5%88%9d%e6%9c%9f%e9%81%8e%e7%a8%8b%e3%81%a7%e7%b4%b0%e8%83%9e%e8%86%9c%e4%b8%8a%e3%81%ae%ce%b1-26-sialic-acids%e3%81%ab%e7%b5%90%e5%90%88%e3%81%99\/","title":{"rendered":"SARS-CoV-2\u306f\u3001\u611f\u67d3\u521d\u671f\u904e\u7a0b\u3067\u7d30\u80de\u819c\u4e0a\u306e\u03b1-(2,6)-sialic acids\u306b\u7d50\u5408\u3059\u308b: \u30df\u30eb\u30af\u30aa\u30ea\u30b4\u7cd6 2-6-sialyl-lactose (6\u2032SL)\u304c\u7d50\u5408\u3092\u963b\u5bb3\u3059\u308b"},"content":{"rendered":"<p>Department of Chemistry, University of California, Davis, Davis, CA, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001SARS-CoV-2\u306e\u5bbf\u4e3b\u7d30\u80de\u819c\u3078\u306e\u7d50\u5408\u306f\u3001\u672b\u7aef\u306b\u03b1-(2,6)-sialic acids\u3092\u6301\u3064\u30b7\u30a2\u30ed\u7cd6\u9396\u306b\u5a92\u4ecb\u3055\u308c\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8964299\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8964299\/<\/a><\/p>\n<p>\u30d2\u30c8\u30df\u30eb\u30af\u30aa\u30ea\u30b4\u7cd6\uff08HMO\uff09\u3092\u3001SARS-CoV-2\u3092HepG2\u7d30\u80de\u306b\u30a2\u30d7\u30e9\u30a4\u3059\u308b\u524d\u306b\u3001SARS-CoV-2\u306eRBD\u3068HMO\u3092\u30d7\u30ec\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30c8\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001RBD\u3092\u30d6\u30ed\u30c3\u30af\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u304c\u30c6\u30b9\u30c8\u3055\u308c\u307e\u3057\u305f\u3002\u86cd\u5149\u6a19\u8b58\u3055\u308c\u305fRBD\u30922&#8242;-FL\u3001LNnT\u3001\u304a\u3088\u30736&#8242;-SL\u3068\u5225\u3005\u306b\u30d7\u30ec\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30c8\u3057\u3001\u6b21\u306b\u5bbf\u4e3b\u7d30\u80deHepG2\u3068\u76f8\u4e92\u4f5c\u7528\u3055\u305b\u307e\u3057\u305f\u3002\u86cd\u5149\u30b7\u30b0\u30ca\u30eb\u5f37\u5ea6\u306e\u5b9a\u91cf\u5316\u306f\u3001HMO\u304c\u304a\u305d\u3089\u304fSARS-CoV-2\u81ea\u4f53\u306e\u6319\u52d5\u3092\u53cd\u6620\u3057\u3066\u3001\u7d30\u80de\u3078\u306eRBD\u306e\u7d50\u5408\u3092\u30d6\u30ed\u30c3\u30af\u3057\u305f\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002 RBD\u306f\u30012&#8217;FL\uff08\u7d71\u8a08\u7684\u306b\u6709\u610f\u3067\u306f\u306a\u3044\uff09\u306b\u3088\u3063\u3066\u308f\u305a\u304b\u306b\u30d6\u30ed\u30c3\u30af\u3055\u308c\u3001LNnT\uff08\u6709\u610f\uff09\u306b\u3088\u3063\u3066\u3055\u3089\u306b\u30d6\u30ed\u30c3\u30af\u3055\u308c\u30016&#8217;SL\u306b\u3088\u3063\u3066\u6700\u3082\u30d6\u30ed\u30c3\u30af\u3055\u308c\u307e\u3057\u305f\u3002 LNnT\u30686&#8217;SL\u306e\u6bd4\u8f03\u306f\u3001\u5f8c\u8005\u306e\u65b9\u304c\u3088\u308a\u52b9\u679c\u7684\uff08\u6709\u610f\uff09\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u30c7\u30fc\u30bf\u306f\u3001HMO\u304cSARS-CoV-2\u306e\u5bbf\u4e3b\u7d30\u80de\u3078\u306e\u63a5\u7740\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u300c\u304a\u3068\u308a\u300d\u3068\u3057\u3066\u6a5f\u80fd\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/04\/HMO-Decoy_SARS-CoV-2-203x300.png\" alt=\"\" width=\"203\" height=\"300\" class=\"alignnone size-medium wp-image-8482\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/04\/HMO-Decoy_SARS-CoV-2-203x300.png 203w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/04\/HMO-Decoy_SARS-CoV-2.png 238w\" sizes=\"auto, (max-width: 203px) 100vw, 203px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Department of Chemistry, University of California, Davis, Davis, CA, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001SARS-CoV-2\u306e\u5bbf\u4e3b\u7d30\u80de\u819c\u3078\u306e\u7d50\u5408\u306f\u3001\u672b\u7aef\u306b\u03b1-(2,<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/sars-cov-2%e3%81%af%e3%80%81%e6%84%9f%e6%9f%93%e5%88%9d%e6%9c%9f%e9%81%8e%e7%a8%8b%e3%81%a7%e7%b4%b0%e8%83%9e%e8%86%9c%e4%b8%8a%e3%81%ae%ce%b1-26-sialic-acids%e3%81%ab%e7%b5%90%e5%90%88%e3%81%99\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-8480","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/8480","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=8480"}],"version-history":[{"count":8,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/8480\/revisions"}],"predecessor-version":[{"id":8489,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/8480\/revisions\/8489"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=8480"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=8480"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=8480"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}