{"id":8400,"date":"2022-03-30T12:39:44","date_gmt":"2022-03-30T03:39:44","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=8400"},"modified":"2022-03-30T12:41:05","modified_gmt":"2022-03-30T03:41:05","slug":"usp-reference-standard-monoclonal-antibodies-with-glycan-structures-nistmab","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/usp-reference-standard-monoclonal-antibodies-with-glycan-structures-nistmab\/","title":{"rendered":"\u30e2\u30ce\u30af\u30ed\u30ca\u30fc\u30eb\u6297\u4f53\u306e\u7cd6\u9396\u4fee\u98fe\u69cb\u9020\u306b\u95a2\u3059\u308b\u30ea\u30d5\u30a1\u30ec\u30f3\u30b9\u30fb\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\uff1aNISTmAb"},"content":{"rendered":"<p>Global Biologics, Science Division, United States Pharmacopeia, Rockville, MD 20852, USA\u3000\u304b\u3089\u8a73\u7d30\u306a\u7cd6\u9396\u4fee\u98fe\u60c5\u5831\u304c\u4ed8\u52a0\u3055\u308c\u305f\u30e2\u30ce\u30af\u30ed\u30ca\u30fc\u30eb\u6297\u4f53\u306e\u30ea\u30d5\u30a1\u30ec\u30f3\u30b9\u30fb\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\uff08RS\uff09\u304c\u516c\u958b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.mdpi.com\/1424-8247\/15\/3\/315\">https:\/\/www.mdpi.com\/1424-8247\/15\/3\/315<\/a><\/p>\n<p>\u8a73\u7d30\u306a\u7cd6\u9396\u4fee\u98fe\u60c5\u5831\u3092\u5099\u3048\u305f\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u30ea\u30d5\u30a1\u30ec\u30f3\u30b9\u30fb\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\u304c\u3001NIST Reference Material 8671\u3001NISTmAb\u3068\u3057\u3066\u3001\u7c73\u56fd\u56fd\u7acb\u6a19\u6e96\u6280\u8853\u7814\u7a76\u6240\u304b\u3089\u5165\u624b\u3067\u304d\u307e\u3059\u3002<br \/>\n\u7c73\u56fd\u85ac\u5c40\u65b9\uff08USP\uff09\u306f\u3001\u7cd6\u9396\u4fee\u98fe\u306e\u7279\u6027\u8a55\u4fa1\u624b\u9806\u304c\u6b63\u78ba\u306a\u7d50\u679c\u3092\u63d0\u4f9b\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u793a\u3059\u305f\u3081\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u6750\u6599\u3068\u3057\u3066\u4f7f\u7528\u3067\u304d\u308b3\u3064\u306e\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u30ea\u30d5\u30a1\u30ec\u30f3\u30b9\u30fb\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\uff08<strong>USP mAb 001 RS\u3001USP mAb 002 RS\u3001\u304a\u3088\u3073USP mAb 003 RS<\/strong>\uff09\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002<br \/>\nUSP mAb\u30ea\u30d5\u30a1\u30ec\u30f3\u30b9\u30fb\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\u306f\u3001\u540c\u3058<strong>IgG type 1\u30b5\u30d6\u30af\u30e9\u30b9<\/strong>\u306e\u7570\u306a\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u304c\u3001\u5e83\u7bc4\u56f2\u306e\u7cd6\u9396\u4fee\u98fe\u69cb\u9020\u3092\u8abf\u3079\u308b\u306e\u306b\u5341\u5206\u306a\u6839\u62e0\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u7cd6\u9396\u4fee\u98fe\u306e\u7279\u6027\u8a55\u4fa1\u306f\u3001\u901a\u5e38\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u9aa8\u683c\u304b\u3089\u5207\u308a\u51fa\u3055\u308c\u305f\u7cd6\u9396\u306e\u89e3\u6790\u306b\u3088\u3063\u3066\u884c\u308f\u308c\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/03\/NISTmAB_with_glycan.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/03\/NISTmAB_with_glycan-300x153.png\" alt=\"\" width=\"300\" height=\"153\" class=\"alignnone size-medium wp-image-8402\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/03\/NISTmAB_with_glycan-300x153.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/03\/NISTmAB_with_glycan-600x305.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/03\/NISTmAB_with_glycan-768x391.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/03\/NISTmAB_with_glycan.png 888w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><br \/>\n\u7cd6\u9396\u69cb\u9020\u306e\u8a18\u53f7\u306e\u610f\u5473\u306f\u3001\u4f8b\u3048\u3070\u4e0b\u8a18\u306e\u3088\u3046\u3067\u3059\u3001<br \/>\n<strong>F(6)A2<\/strong>: core fucosylated biantennary\u3001<br \/>\n<strong>F(6)A2B<\/strong>: core fucosylated biantennary with bisecting GlcNAc\u3001<br \/>\nM5: five mannose on core GlcNAc\u3001<br \/>\n<strong>F(6)A1G(4)1<\/strong>: core fucosylated monoantennary with \u03b21-4 linked Galactose\u3001<br \/>\n<strong>A2[6]G(4)1<\/strong>: biantennary with \u03b21-4 linked Galactose attached to \u03b11-6 linked core mannose\u3001<br \/>\n<strong>F(6)A2[6]G(4)1<\/strong>: core fucosylated biantennary with \u03b21-4 linked Galactose attached to \u03b11-6 linked core mannose\u3001<br \/>\n<strong>F(6)A2[3]G(4)1<\/strong>: core fucosylated biantennary with \u03b21-4 linked Galactose attached to \u03b11-3 linked core mannose\u3001<br \/>\n<strong>F(6)A2[6]G(4)1Ga1<\/strong>: fucosylated bianntennary with a \u03b21,4-linked galactose directly attached to the \u03b11,6-linked core mannose, and an \u03b11,3-linked galactose attached to the \u03b21,4-linked galactose<br \/>\n<strong>F(6)A2G(4)2<\/strong>: equal to G2F\u3001<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Global Biologics, Science Division, United States Pharmacopeia, Rockville, MD 20852, USA\u3000\u304b\u3089\u8a73\u7d30\u306a\u7cd6\u9396\u4fee\u98fe\u60c5\u5831\u304c\u4ed8\u52a0\u3055\u308c\u305f\u30e2\u30ce\u30af\u30ed<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/usp-reference-standard-monoclonal-antibodies-with-glycan-structures-nistmab\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-8400","post","type-post","status-publish","format-standard","hentry","category-technology-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"Global Biologics, Science Division, United States Pharm\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.emukk.com\/WP\/usp-reference-standard-monoclonal-antibodies-with-glycan-structures-nistmab\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.0.1\" \/>\n\t\t<meta property=\"og:locale\" content=\"ja_JP\" \/>\n\t\t<meta property=\"og:site_name\" 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