{"id":7993,"date":"2022-02-20T13:17:53","date_gmt":"2022-02-20T04:17:53","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=7993"},"modified":"2022-02-20T16:57:41","modified_gmt":"2022-02-20T07:57:41","slug":"hiv%e6%84%9f%e6%9f%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e3%82%a8%e3%83%b3%e3%83%99%e3%83%ad%e3%83%bc%e3%83%97%e3%81%ae%e7%b3%96%e9%8e%96%e3%81%a8%e5%ae%bf","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/hiv%e6%84%9f%e6%9f%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e3%82%a8%e3%83%b3%e3%83%99%e3%83%ad%e3%83%bc%e3%83%97%e3%81%ae%e7%b3%96%e9%8e%96%e3%81%a8%e5%ae%bf\/","title":{"rendered":"HIV\u611f\u67d3\u306b\u304a\u3051\u308b\u30a6\u30a4\u30eb\u30b9\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u306e\u7cd6\u9396\u3068\u5bbf\u4e3b\u7d30\u80de\u8868\u9762\u306e\u7cd6\u9396\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306e\u91cd\u8981\u6027"},"content":{"rendered":"<p>Institute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001HIV\u611f\u67d3\u306b\u304a\u3051\u308b\u7cd6\u9396\uff70\u7cd6\u9396\u76f8\u4e92\u4f5c\u7528\u306e\u91cd\u8981\u6027\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(22)00002-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS221112472200002X%3Fshowall%3Dtrue\">Host glycocalyx captures HIV proximal to the cell surface via<\/a><\/p>\n<p>HIV\u306e\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u306b\u5b58\u5728\u3059\u308b\u7cd6\u9396\u306e\u5f79\u5272\u306b\u95a2\u3057\u3066\u306f\u3001\u73fe\u5728\u6b21\u306e\u3088\u3046\u306a\u4e8b\u67c4\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\uff1a\uff081\uff09\u30d2\u30c8\u306e\u514d\u75ab\u8a8d\u8b58\u304b\u3089HIV\u3092\u4fdd\u8b77\u3059\u308b\u3001\uff082\uff09\u4e09\u91cf\u4f53\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u69cb\u9020\u3092\u5b89\u5b9a\u5316\u3055\u305b\u308b\u3001\uff083\uff09\u7cd6\u9396\u3068\u5bbf\u4e3b\u7d30\u80de\u5074\u306e\u30ec\u30af\u30c1\u30f3\u3068\u306e\uff08\u9759\u96fb\u7684\uff09\u76f8\u4e92\u4f5c\u7528\u3092\u4ecb\u3057\u3066T\u30ea\u30f3\u30d1\u7403\u306e\u30c8\u30e9\u30f3\u30b9\u611f\u67d3\u3092\u5a92\u4ecb\u3059\u308b\u3002<\/p>\n<p>\u826f\u304f\u77e5\u3089\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u3001HIV\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u306b\u306f\u3001\u7d0430\u500b\u306eN-\u578b\u7cd6\u9396\u7d50\u5408\u90e8\u4f4d\u304c\u5b58\u5728\u3057\u3001\u3053\u308c\u3089\u306e\u90e8\u4f4d\u306e\u591a\u304f\u306f\u3001Man <sub>5-9<\/sub>GlcNAc<sub>2<\/sub> -Asn\u3001\u304a\u3088\u3073Man<sub>3<\/sub>GlcNAc<sub>2<\/sub> -Asn\u30b3\u30a2\u69cb\u9020\u3092\u542b\u3080\u30aa\u30ea\u30b4\u30de\u30f3\u30ce\u30fc\u30b9N-\u578b\u7cd6\u9396\u3067\u4e3b\u306b\u4fee\u98fe\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>HIV\u306e\u4fb5\u5165\u306b\u3064\u3044\u3066\u306f\u591a\u304f\u306e\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001HIV\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u3068CD4\u53d7\u5bb9\u4f53\u4f9d\u5b58\u6027\u76f8\u4e92\u4f5c\u7528\u306e\u524d\u6bb5\u968e\u306b\u5b58\u5728\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u30a6\u30a4\u30eb\u30b9\u3068\u7d30\u80de\u9593\u306e\u6700\u521d\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\u306f\u3001\u4f9d\u7136\u3068\u3057\u3066\u304b\u306a\u308a\u4e0d\u660e\u78ba\u306a\u307e\u307e\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u30ec\u30dd\u30fc\u30c8\u3067\u306f\u3001\u7cd6\u9396-\u7cd6\u9396\u76f8\u4e92\u4f5c\u7528\u304cHIV\u3068\u5bbf\u4e3b\u7d30\u80de\u306e\u63a5\u89e6\u3092\u958b\u59cb\u3055\u305b\u308b\u3001\u3064\u307e\u308a\u3001HIV\u3068\u5bbf\u4e3b\u7d30\u80de\u305e\u308c\u305e\u308c\u306b\u5b58\u5728\u3059\u308b\u7cd6\u9396\u306e\u76f8\u4e92\u4f5c\u7528\u304c\u3001HIV\u306e\u4ee3\u8868\u7684\u306a\u672b\u7aefN-\u578b\u7cd6\u9396\u69cb\u9020\u3067\u3042\u308b\u30aa\u30ea\u30b4\u30de\u30f3\u30ce\u30fc\u30b9Man5(Man\u03b11-3Man\u03b11-6[Man\u03b11-3] Man\u3068\u5bbf\u4e3b\u7d30\u80de\u306b\u5b58\u5728\u3059\u308bGlcNAc\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u4ecb\u3057\u3066\u884c\u308f\u308c\u308b\u3053\u3068\u3067\u3001HIV\u306e\u5bbf\u4e3b\u7d30\u80de\u3078\u306e\u63a5\u7740\u3092\u5897\u5f37\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u305f\u306e\u3067\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/02\/HIV_glycan-glycan-interactions.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/02\/HIV_glycan-glycan-interactions-300x247.png\" alt=\"\" width=\"300\" height=\"247\" class=\"alignnone size-medium wp-image-8013\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/02\/HIV_glycan-glycan-interactions-300x247.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/02\/HIV_glycan-glycan-interactions.png 456w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u3064\u307e\u308a\u3001\u7cd6\u9396-\u7cd6\u9396\u76f8\u4e92\u4f5c\u7528\u304c\u3001\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306b\u304a\u3051\u308b\u65b0\u3057\u3044\u30af\u30e9\u30b9\u306e\u9ad8\u30a2\u30d5\u30a3\u30cb\u30c6\u30a3\u30fc\u751f\u4f53\u5206\u5b50\u9593\u76f8\u4e92\u4f5c\u7528\u3068\u3057\u3066\u30af\u30ed\u30fc\u30ba\u30a2\u30c3\u30d7\u3055\u308c\u3066\u304d\u305f\u3068\u8a00\u3048\u308b\u306e\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Institute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001HIV\u611f\u67d3\u306b\u304a\u3051\u308b\u7cd6\u9396\uff70\u7cd6\u9396\u76f8\u4e92\u4f5c\u7528\u306e\u91cd\u8981\u6027\u306b\u3064\u3044\u3066<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/hiv%e6%84%9f%e6%9f%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e3%82%a8%e3%83%b3%e3%83%99%e3%83%ad%e3%83%bc%e3%83%97%e3%81%ae%e7%b3%96%e9%8e%96%e3%81%a8%e5%ae%bf\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-7993","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Institute for Glycomics, Griffith University, Gold Coas\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" 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