{"id":7742,"date":"2022-02-09T11:49:27","date_gmt":"2022-02-09T02:49:27","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=7742"},"modified":"2022-02-09T12:35:04","modified_gmt":"2022-02-09T03:35:04","slug":"%e3%82%ad%e3%83%81%e3%83%8a%e3%83%bc%e3%82%bc3-like-1%ef%bc%88chi3l1%ef%bc%89%e3%81%ae%e9%98%bb%e5%ae%b3%e5%89%a4%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e3%82%ad%e3%83%81%e3%83%8a%e3%83%bc%e3%82%bc3-like-1%ef%bc%88chi3l1%ef%bc%89%e3%81%ae%e9%98%bb%e5%ae%b3%e5%89%a4%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab\/","title":{"rendered":"\u30ad\u30c1\u30ca\u30fc\u30bc3-like-1\uff08CHI3L1\uff09\u306e\u963b\u5bb3\u5264\u304c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u611f\u67d3\u306e\u6cbb\u7642\u85ac\u306b\u306a\u308a\u5f97\u308b\uff1a\u6297-CHI3L1\u304a\u3088\u3073\u30ab\u30b9\u30ac\u30de\u30a4\u30b7\u30f3"},"content":{"rendered":"<p>Molecular Microbiology and Immunology, Brown University, RI. 02912, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6297-\u30ad\u30c1\u30ca\u30fc\u30bc3-like-1\uff08CHI3L1\uff09\u3001\u304a\u3088\u3073\u4f4e\u5206\u5b50\u5316\u5408\u7269\u3067\u3042\u308bCHI3L1\u306e\u963b\u5bb3\u5264\u3067\u3042\u308b\u30ab\u30b9\u30ac\u30de\u30a4\u30b7\u30f3\u304c\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306e\u6cbb\u7642\u85ac\u306b\u306a\u308a\u5f97\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.01.21.477274v1\">https:\/\/www.biorxiv.org\/content\/10.1101\/2022.01.21.477274v1<\/a><\/p>\n<p>CHI3L1\u306e\u3088\u3046\u306aSARS-CoV-2\u611f\u67d3\u306b\u95a2\u4e0e\u3059\u308b\u5bbf\u4e3b\u56e0\u5b50\u3092\u6a19\u7684\u3068\u3059\u308b\u6cbb\u7642\u6cd5\u306f\u3001ACE2\u3092\u4f7f\u7528\u3059\u308b\u3059\u3079\u3066\u306e\u30a6\u30a4\u30eb\u30b9\u5909\u7570\u4f53\u306e\u611f\u67d3\u5236\u5fa1\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3053\u306e\u4eee\u8aac\u3092\u30c6\u30b9\u30c8\u3059\u308b\u305f\u3081\u306b\u3001\u30a2\u30eb\u30d5\u30a1\u3001\u30d9\u30fc\u30bf\u3001\u30ac\u30f3\u30de\u3001\u30c7\u30eb\u30bf\u3001\u304a\u3088\u3073\u30aa\u30df\u30af\u30ed\u30f3\u5909\u7570\u682a\u306eSpike\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u767a\u73fe\u3059\u308b\u507d\u30a6\u30a4\u30eb\u30b9\u3092\u8abf\u88fd\u3057\u3001CHI3L1\u30d9\u30fc\u30b9\u306e\u4ecb\u5165\u304c\u30d2\u30c8\u80ba\u4e0a\u76ae\u7d30\u80de\u306b\u611f\u67d3\u3059\u308b\u80fd\u529b\u3092\u5236\u5fa1\u3067\u304d\u308b\u304b\u5426\u304b\u304c\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u3067\u306f\u3001CHI3L1\u304c\u5bbf\u4e3b\u7d30\u80de\u306b\u304a\u3051\u308bACE2\u304a\u3088\u3073Spike\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30d7\u30e9\u30a4\u30df\u30f3\u30b0\u9175\u7d20\u306e\u767a\u73fe\u3068\u84c4\u7a4d\u3092\u5897\u5f37\u3057\u3001\u30a2\u30eb\u30d5\u30a1\u3001\u30d9\u30fc\u30bf\u3001\u30ac\u30f3\u30de\u3001\u30c7\u30eb\u30bf\u3001\u304a\u3088\u3073\u30aa\u30df\u30af\u30ed\u30f3\u5909\u7570\u682a\u306e\u507d\u30a6\u30a4\u30eb\u30b9\u5909\u7570\u4f53\u306b\u3088\u308b\u80ba\u4e0a\u7d30\u80de\u3078\u306e\u611f\u67d3\u3092\u5897\u5f37\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u307e\u305f\u3001\u6297-CHI3L1\u304c\u80ba\u4e0a\u76ae\u7d30\u80de\u306b\u304a\u3051\u308bACE2\u3068Spike\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30d7\u30e9\u30a4\u30df\u30f3\u30b0\u9175\u7d20\u306e\u767a\u73fe\u3068\u84c4\u7a4d\u3092\u963b\u5bb3\u3057\u3001\u30a2\u30eb\u30d5\u30a1\u3001\u30d9\u30fc\u30bf\u3001\u30ac\u30f3\u30de\u3001\u30c7\u30eb\u30bf\u3001\u304a\u3088\u3073\u30aa\u30df\u30af\u30ed\u30f3\u5909\u7570\u682a\u306e\u507d\u30a6\u30a4\u30eb\u30b9\u306b\u3088\u308b\u80ba\u4e0a\u76ae\u7d30\u80de\u3078\u306e\u611f\u67d3\u3092\u963b\u5bb3\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/02\/CHI3L1-FRG_SARS-CoV-2-infection.png\" alt=\"\" width=\"481\" height=\"279\" class=\"alignnone size-full wp-image-7747\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/02\/CHI3L1-FRG_SARS-CoV-2-infection.png 481w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/02\/CHI3L1-FRG_SARS-CoV-2-infection-300x174.png 300w\" sizes=\"auto, (max-width: 481px) 100vw, 481px\" \/>\u3000<br \/>\nCHI3L1\u304cCalu-3\u7d30\u80de\u306eACE2\u767a\u73fe\u3068\u30c7\u30eb\u30bf\u682a\u507d\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u3092\u5897\u5f37\u3057\u3001<strong>FRG\uff08\u6297-CHI3L1\uff09<\/strong>\u304c\u3001ACE2\u3068\u30c7\u30eb\u30bf\u507d\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306e\u767a\u73fe\u3092\u6291\u5236\u3057\u305f\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f<\/p>\n<p><strong>\u30ab\u30b9\u30ac\u30de\u30a4\u30b7\u30f3<\/strong>\u306e\u5834\u5408\u306b\u3082\u540c\u69d8\u306e\u6297\u30a6\u30a4\u30eb\u30b9\u6d3b\u6027\u304c\u89b3\u5bdf\u3055\u308c\u3001\u30a2\u30eb\u30d5\u30a1\u3001\u30d9\u30fc\u30bf\u3001\u30ac\u30f3\u30de\u3001\u307e\u305f\u306f\u30c7\u30eb\u30bf\u5909\u7570\u682a\u306eS\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6301\u3064\u507d\u30a6\u30a4\u30eb\u30b9\u306e\u53d6\u308a\u8fbc\u307f\u3092\u52b9\u679c\u7684\u306b\u963b\u5bb3\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Molecular Microbiology and Immunology, Brown University, RI. 02912, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6297-\u30ad\u30c1\u30ca\u30fc\u30bc3-like-1\uff08CHI3L1\uff09\u3001\u304a\u3088\u3073\u4f4e\u5206\u5b50\u5316<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e3%82%ad%e3%83%81%e3%83%8a%e3%83%bc%e3%82%bc3-like-1%ef%bc%88chi3l1%ef%bc%89%e3%81%ae%e9%98%bb%e5%ae%b3%e5%89%a4%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-7742","post","type-post","status-publish","format-standard","hentry","category-technology-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7742","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=7742"}],"version-history":[{"count":17,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7742\/revisions"}],"predecessor-version":[{"id":7768,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7742\/revisions\/7768"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=7742"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=7742"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=7742"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}