{"id":7461,"date":"2022-01-18T11:19:45","date_gmt":"2022-01-18T02:19:45","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=7461"},"modified":"2022-01-18T11:20:01","modified_gmt":"2022-01-18T02:20:01","slug":"%e4%be%b5%e8%a5%b2%e6%80%a7%e3%81%ae%e7%99%8c%e3%81%ab%e3%81%af%e3%80%81%ce%b1-galnac%e3%81%8c%e7%99%ba%e7%8f%be%e3%81%97%e3%81%a6%e3%81%84%e3%82%8b","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e4%be%b5%e8%a5%b2%e6%80%a7%e3%81%ae%e7%99%8c%e3%81%ab%e3%81%af%e3%80%81%ce%b1-galnac%e3%81%8c%e7%99%ba%e7%8f%be%e3%81%97%e3%81%a6%e3%81%84%e3%82%8b\/","title":{"rendered":"\u4fb5\u8972\u6027\u306e\u764c\u306b\u306f\u3001\u03b1-GalNAc\u304c\u9ad8\u767a\u73fe\u3057\u3066\u3044\u308b"},"content":{"rendered":"<p>University of Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu, Finland\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001<strong>Helix Pomatia agglutinin (HPA)<\/strong>\u30ec\u30af\u30c1\u30f3\u306b\u3088\u3063\u3066\u8a8d\u8b58\u3055\u308c\u308b<strong>\u03b1-GalNAc<\/strong>\u306e\u767a\u73fe\u30ec\u30d9\u30eb\u304c\u3001\u764c\u306e\u4fb5\u8972\u6027\u3068\u9855\u8457\u306b\u76f8\u95a2\u3057\u3066\u3044\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8751650\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8751650\/<\/a><\/p>\n<p>\u8457\u8005\u3089\u306f\u3001\u30ec\u30af\u30c1\u30f3\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u3092\u7528\u3044\u3089\u7cd6\u9396\u30d7\u30ed\u30d5\u30a1\u30a4\u30ea\u30f3\u30b0\u3092\u4f7f\u7528\u3057\u3066\u3001\u4fb5\u8972\u6027\u306e\u7570\u306a\u308b9\u3064\u306e\u764c\u7d30\u80de\u682a\u306e\u7cd6\u9396\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6bd4\u8f03\u89e3\u6790\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u30ec\u30af\u30c1\u30f3\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u306b\u642d\u8f09\u3055\u308c\u3066\u3044\u308b43\u500b\u306e\u30ec\u30af\u30c1\u30f3\u306e\u5185\u30015\u500b\u306e\u30ec\u30af\u30c1\u30f3\uff08<strong> HPA\u3001PTL-1\u3001AJA\u3001MAL I\u3001PWM <\/strong>\uff09\u306e\u307f\u304c\u764c\u306e\u4fb5\u8972\u6027\u3068\u6b63\u307e\u305f\u306f\u8ca0\u306e\u76f8\u95a2\u3092\u793a\u3059\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u591a\u5909\u91cf\u7dda\u5f62\u56de\u5e30\u5206\u6790\u304b\u3089\u306f\u3001\u3053\u308c\u3089\u306e5\u3064\u306e\u30ec\u30af\u30c1\u30f3\u304c\u764c\u7d30\u80de\u306e\u4fb5\u8972\u6027\u8868\u73fe\u578b\u3067\u89b3\u5bdf\u3055\u308c\u305f\u5909\u52d5\u306e97\uff05\u3092\u5360\u3081\u3001HPA\u306e\u307f\u3082\u5909\u52d5\u306e58\uff05\u3092\u5360\u3081\u3001PTL-1\u3068HPA\u3092\u5408\u308f\u305b\u308b\u3068\u5909\u52d5\u306e76\uff05\u3092\u5360\u3081\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u6b8b\u308a\u306e\u30ec\u30af\u30c1\u30f3\uff08AJA\u3001MAL I\u3001PWM\uff09\u306f\u8ca0\u306e\u76f8\u95a2\u3092\u793a\u3057\u3001\u305d\u308c\u305e\u308c7\uff05\u306e\u5bc4\u4e0e\u3067\u3057\u305f\u3002\u5f93\u3063\u3066\u3001\u764c\u7d30\u80de\u306b\u304a\u3051\u308bHPA\u7d50\u5408\u578b\u6027\u306e\u7cd6\u9396\u30a8\u30d4\u30c8\u30fc\u30d7\uff08O-\u7d50\u5408\u578b\u03b1-GalNAc\uff09\u306e\u767a\u73fe\u306e\u5897\u52a0\u304c\u3001\u764c\u7d30\u80de\u306e\u4fb5\u8972\u6027\u3092\u4fc3\u9032\u3059\u308b\u4e3b\u306a\u8981\u56e0\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u6b21\u306b\u3001HPA\u7d50\u5408\u6027\u30bf\u30f3\u30d1\u30af\u8cea\u3092HPA\u30ec\u30af\u30c1\u30f3\u3067\u30d7\u30eb\u30c0\u30a6\u30f3\u3057\u3001LC-MS\/MS\u3067\u540c\u5b9a\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u308c\u3089\u306e\u3046\u3061\u3001HPA\u3067\u514d\u6c88\u3057\u305f\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\uff08<strong> EGFR\u3001MMP-14\u3001\u03b24-\u3001\u03b21-\u3001\u03b12-\u3001\u304a\u3088\u3073\u03b1V\u30a4\u30f3\u30c6\u30b0\u30ea\u30f3<\/strong>\uff09\u306f\u3001\u4f4e\u4fb5\u8972\u6027\u7d30\u80de\u3068\u6bd4\u8f03\u3057\u3066\u9ad8\u4fb5\u8972\u6027\u7d30\u80de\u3067\u8457\u3057\u304f\u6fc3\u7e2e\u3055\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u672b\u7aef\u03b1-GalNAc\u306e\u4fee\u98fe\u30ec\u30d9\u30eb\u304c\u5897\u52a0\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5185\u3001<strong> EGFR\u304a\u3088\u3073\u03b12\u30a4\u30f3\u30c6\u30b0\u30ea\u30f3<\/strong>\u304c\u764c\u306e\u4fb5\u8972\u6027\u3068\u6709\u610f\u306b\u76f8\u95a2\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u5224\u660e\u3057\u307e\u3057\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu, Finland\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001Helix Pomatia aggluti<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e4%be%b5%e8%a5%b2%e6%80%a7%e3%81%ae%e7%99%8c%e3%81%ab%e3%81%af%e3%80%81%ce%b1-galnac%e3%81%8c%e7%99%ba%e7%8f%be%e3%81%97%e3%81%a6%e3%81%84%e3%82%8b\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-7461","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=7461"}],"version-history":[{"count":10,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7461\/revisions"}],"predecessor-version":[{"id":7471,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7461\/revisions\/7471"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=7461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=7461"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=7461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}