{"id":7408,"date":"2022-01-12T20:53:02","date_gmt":"2022-01-12T11:53:02","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=7408"},"modified":"2022-01-12T21:38:34","modified_gmt":"2022-01-12T12:38:34","slug":"car-nk%e7%b4%b0%e8%83%9e%e3%82%92sars-cov-2%e6%84%9f%e6%9f%93%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab%e4%bd%bf%e7%94%a8%e3%81%99%e3%82%8b","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/car-nk%e7%b4%b0%e8%83%9e%e3%82%92sars-cov-2%e6%84%9f%e6%9f%93%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab%e4%bd%bf%e7%94%a8%e3%81%99%e3%82%8b\/","title":{"rendered":"\u30ad\u30e1\u30e9\u6297\u539f\u53d7\u5bb9\u4f53\uff08CAR\uff09-NK\u7d30\u80de\u3092SARS-CoV-2\u611f\u67d3\u306e\u6cbb\u7642\u306b\u4f7f\u7528\u3059\u308b"},"content":{"rendered":"<p>The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001SARS-CoV-2\u611f\u67d3\u306e\u6cbb\u7642\u306e\u305f\u3081\u306e\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u6a19\u7684\u30ad\u30e1\u30e9\u6297\u539f\u53d7\u5bb9\u4f53\uff08CAR\uff09-NK\u7d30\u80de\u3092\u4f7f\u7528\u3057\u305f\u65b0\u3057\u3044\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u63d0\u6848\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8732772\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8732772\/<\/a><\/p>\n<p>NK\u7d30\u80de\u306f\u514d\u75ab\u7cfb\u306e\u81ea\u7136\u514d\u75ab\u30ea\u30f3\u30d1\u7403\u3067\u3042\u308a\u3001\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306e\u5236\u5fa1\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u304a\u308a\u3001CAR-T\u7d30\u80de\u304a\u3088\u3073CAR-NK\u7d30\u80de\u306f\u3001\u764c\u3084\u611f\u67d3\u75c7\u306b\u5bfe\u3059\u308b\u975e\u5e38\u306b\u6709\u671b\u306a\u65b0\u3057\u3044\u514d\u75ab\u7642\u6cd5\u3068\u3057\u3066\u7740\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u901a\u5e38\u3001NK\u7d30\u80de\u8868\u9762\u306b\u767a\u73fe\u3055\u308c\u305f\u5408\u6210\u53d7\u5bb9\u4f53\u306f\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u7d30\u80de\u306e\u8868\u9762\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7d50\u5408\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u306a\u308b\u7cd6\u9396\u4fee\u98fe\u306b\u5bfe\u3059\u308b\u7d50\u5408\u7279\u6027\u3092\u6301\u3064\u30e6\u30cb\u30fc\u30af\u306a\u7d30\u80de\u819c\u5916\u767a\u73fe\u5206\u5b50\uff08\u5373\u3061\u3001\u30ec\u30af\u30c1\u30f3\uff09\u3092\u5229\u7528\u3057\u3066CAR\u3092\u8a2d\u8a08\u3057\u307e\u3057\u305f\u3002\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u7279\u306bN-\u578b\u7cd6\u9396\u3092CAR\u3067\u6a19\u7684\u5316\u3059\u308b\u3053\u3068\u306f\u307e\u308c\u3067\u3059\u3002\u672c\u7814\u7a76\u306f\u3001SARS-CoV-2\u306eSpike\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u767a\u73fe\u3057\u305fN\uff70\u578b\u7cd6\u9396\u3092\u6a19\u7684\u3068\u3059\u308b\u6700\u521d\u306eCAR\u3067\u3042\u308a\u3001\u304a\u305d\u3089\u304f\u3001\u524d\u81e8\u5e8a\u8a66\u9a13\u3067\u8a2d\u8a08\u304a\u3088\u3073\u6a5f\u80fd\u7684\u306b\u30c6\u30b9\u30c8\u3055\u308c\u305f\u6700\u521d\u306e\u30ec\u30af\u30c1\u30f3\u30d9\u30fc\u30b9\u306eCAR\u3067\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u30ec\u30af\u30c1\u30f3\u306f\u3001\u4f55\u767e\u4e07\u5e74\u306b\u3082\u308f\u305f\u3063\u3066\u7cd6\u9396\u306b\u5bfe\u3057\u3066\u975e\u5e38\u306b\u5f37\u529b\u3067\u9078\u629e\u7684\u306a\u7d50\u5408\u7279\u6027\u3092\u6301\u3064\u3088\u3046\u306b\u9032\u5316\u3057\u3066\u304d\u305f\u3082\u306e\u3067\u3042\u308a\u3001H84T-BanLec CAR\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u306a\u7cd6\u9396\u4fee\u98fe\u30d1\u30bf\u30fc\u30f3\uff08\u3053\u306e\u5834\u5408\u306f\u30cf\u30a4\u30fb\u30de\u30f3\u30ce\u30fc\u30b9\uff09\u3092\u6a19\u7684\u3068\u3059\u308b\u3068\u3044\u3046\u70b9\u3067\u3001\u307e\u3063\u305f\u304f\u65b0\u3057\u3044\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3059\u3002\u3053\u3053\u3067\u3001BanLec\u306f\u3001\u30cf\u30a4\u30fb\u30de\u30f3\u30ce\u30fc\u30b9\u578b\u7cd6\u9396\u3078\u306e\u7d50\u5408\u7279\u7570\u6027\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u30ec\u30af\u30c1\u30f3\u3067\u3042\u308a\u3001SARS-CoV-2 Spike\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u53d7\u5bb9\u4f53\u7d50\u5408\u30c9\u30e1\u30a4\u30f3\u306e\u8fd1\u304f\u306b\u5b58\u5728\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>SARS-CoV-2\u306a\u3069\u306eRNA\u30a6\u30a4\u30eb\u30b9\u306b\u304a\u3044\u3066\u306f\u3001\u30b2\u30ce\u30e0\u306e\u7a81\u7136\u5909\u7570\u306e\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u3044\u53d7\u5bb9\u4f53\u30bf\u30fc\u30b2\u30c6\u30a3\u30f3\u30b0\u30d1\u30bf\u30fc\u30f3\u3092\u5099\u3048\u305fCAR\u3092\u958b\u767a\u3059\u308b\u5fc5\u8981\u6027\u304c\u3042\u308a\u3001N-\u578b\u7cd6\u9396\u306f\u305d\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u6210\u308a\u3046\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/car-nk%e7%b4%b0%e8%83%9e%e3%82%92sars-cov-2%e6%84%9f%e6%9f%93%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab%e4%bd%bf%e7%94%a8%e3%81%99%e3%82%8b\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642,42],"tags":[],"class_list":["post-7408","post","type-post","status-publish","format-standard","hentry","category-nature-ja","category-technology-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7408","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=7408"}],"version-history":[{"count":13,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7408\/revisions"}],"predecessor-version":[{"id":7423,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/7408\/revisions\/7423"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=7408"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=7408"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=7408"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}