{"id":7176,"date":"2021-12-16T07:12:37","date_gmt":"2021-12-15T22:12:37","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=7176"},"modified":"2021-12-16T07:12:37","modified_gmt":"2021-12-15T22:12:37","slug":"%e7%b7%91%e8%86%bf%e8%8f%8c%ef%bc%88%e3%82%b7%e3%83%a5%e3%83%bc%e3%83%89%e3%83%a2%e3%83%8a%e3%82%b9%e3%83%bb%e3%82%a2%e3%83%ab%e3%82%ae%e3%83%8e%e3%83%bc%e3%82%b6%ef%bc%89%e3%81%ae%e6%85%a2%e6%80%a7","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e7%b7%91%e8%86%bf%e8%8f%8c%ef%bc%88%e3%82%b7%e3%83%a5%e3%83%bc%e3%83%89%e3%83%a2%e3%83%8a%e3%82%b9%e3%83%bb%e3%82%a2%e3%83%ab%e3%82%ae%e3%83%8e%e3%83%bc%e3%82%b6%ef%bc%89%e3%81%ae%e6%85%a2%e6%80%a7\/","title":{"rendered":"\u7dd1\u81bf\u83cc\uff08\u30b7\u30e5\u30fc\u30c9\u30e2\u30ca\u30b9\u30fb\u30a2\u30eb\u30ae\u30ce\u30fc\u30b6\uff09\u306e\u6162\u6027\u611f\u67d3\u306b\u304a\u3051\u308bC\u578b\u30ec\u30af\u30c1\u30f3\u306e\u5f79\u5272"},"content":{"rendered":"<p>School of Life Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u7dd1\u81bf\u83cc\u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u306b\u3088\u308b\u6162\u6027\u611f\u67d3\u6642\u306e\u514d\u75ab\u5fdc\u7b54\u306e\u8abf\u7bc0\u306b\u304a\u3051\u308bC\u578b\u30ec\u30af\u30c1\u30f3\u306e\u6f5c\u5728\u7684\u306a\u5f79\u5272\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.nature.com\/articles\/s41522-021-00257-w\">https:\/\/www.nature.com\/articles\/s41522-021-00257-w<\/a><\/p>\n<p>\u7dd1\u81bf\u83cc\uff08\u30b7\u30e5\u30fc\u30c9\u30e2\u30ca\u30b9\u30fb\u30a2\u30eb\u30ae\u30ce\u30fc\u30b6\uff09\u306f\u3001\u5207\u308a\u50b7\u3084\u706b\u50b7\u306e\u5f8c\u306b\u6025\u6027\u611f\u67d3\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u6301\u7d9a\u6027\u306e\u80ba\u75be\u60a3\u3084\u514d\u75ab\u529b\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u60a3\u8005\u306b\u6162\u6027\u611f\u67d3\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u65e5\u548c\u898b\u75c5\u539f\u83cc\u3067\u3059\u3002<\/p>\n<p>\u672c\u7814\u7a76\u3067\u3001\u5e7e\u3064\u304b\u306e\u4e8b\u67c4\u304c\u660e\u78ba\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\n(i) \u7dd1\u81bf\u83cc\u304c\u3001DC-SIGN (CD209)\u306b\u3088\u3063\u3066\u5f37\u304f\u8a8d\u8b58\u3055\u308c\u3001MR (CD206) \u3084 Dectin-2\u306b\u3088\u3063\u3066\u5f31\u304f\u8a8d\u8b58\u3055\u308c\u308b\u3001<br \/>\n(ii) \u7dd1\u81bf\u83cc\u306e\u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u3092\u69cb\u6210\u3059\u308b\u7cd6\u9396\u3001\u7279\u306b\u9ad8\u5206\u5b50\u91cf\u306e\u305d\u308c\u306b\u3001DC-SIGN\u3001MR\u3001Dectin-2\u304c\u7d50\u5408\u3059\u308b\u3001<br \/>\n(iii) \u3053\u308c\u3089\u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u304c\u3001DC-SIGN\u3001MR\u3001Dectin-2 \u306e\u6a5f\u80fd\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u305d\u3057\u3066<br \/>\n(iv) \u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u306e\u7cd6\u9396\u304c\u6a39\u72b6\u7d30\u80de\u306e\u8868\u73fe\u578b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<br \/>\n\u3053\u306e\u7814\u7a76\u306e\u91cd\u8981\u306a\u30e1\u30c3\u30bb\u30fc\u30b8\u306f\u3001\u7dd1\u81bf\u83cc\u304c\u3001C\u578b\u30ec\u30af\u30c1\u30f3\u306e\u95a2\u4e0e\u3092\u901a\u3058\u3066\u514d\u75ab\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u7cd6\u9396\u3092\u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u3068\u3057\u3066\u751f\u6210\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n<p>\u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u304b\u3089\u306e\u7cd6\u9396\u3092\u7cbe\u88fd\u3057\u3001\u30b2\u30eb\u308d\u904e\u30af\u30ed\u30de\u30c8\u30b0\u30e9\u30d5\u30a3\u30fc\u3067\u5206\u6790\u3057\u305f\u7d50\u679c\u3001\u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u306e\u7cd6\u9396\u306f\u3001\u9ad8\u5206\u5b50\u91cf\uff08> 45 kDa\u3001HMW\uff09\u3068\u4f4e\u5206\u5b50\u91cf\uff08<45 kDa\u3001LMW\uff09\u3068\u3044\u3046\u5927\u304d\u304f\u4e8c\u3064\u306e\u753b\u5206\u306b\u5206\u3051\u3089\u308c\u307e\u3057\u305f\u3002\u66f4\u306b\u3001HMW\u3068LMW\u306e\u5206\u5b50\u91cf\u306e\u9055\u3044\u3092\u8a73\u7d30\u306b\u5206\u6790\u3057\u305f\u7d50\u679c\u3001LMW\uff1d15,370 Da\u3001HMW-1\u3068HMW-2\u306f\u305d\u308c\u305e\u308c\u3001182,300Da\u3068132,670Da\u3068\u3044\u3046\u4e8c\u3064\u306e\u753b\u5206\u306b\u5206\u304b\u308c\u307e\u3057\u305f\u3002HMW-1\u306e\u7cd6\u9396\u306e\u30e2\u30ce\u30de\u30fc\u7d44\u6210\u306f\u300174.9\uff05\u30de\u30f3\u30ce\u30fc\u30b9\u300114.7\uff05\u30b0\u30eb\u30b3\u30fc\u30b9\u30017.4\uff05\u30ac\u30e9\u30af\u30c8\u30fc\u30b9\u3001\u304a\u3088\u30733.0\uff05\u30e9\u30e0\u30ce\u30fc\u30b9\u3067\u3042\u308a\u3001HMW-2\u306e\u5834\u5408\u300180.9\uff05\u30de\u30f3\u30ce\u30fc\u30b9\u300111.0\uff05\u30b0\u30eb\u30b3\u30fc\u30b9\u30012.3\uff05\u30ac\u30e9\u30af\u30c8\u30fc\u30b9\u3001\u304a\u3088\u30735.7\uff05\u30e9\u30e0\u30ce\u30fc\u30b9\u3067\u3057\u305f\u3002\n\n<a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/12\/biofilms-and-C-type-lectins_pseudomonas-aeruginosa.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/12\/biofilms-and-C-type-lectins_pseudomonas-aeruginosa-300x90.png\" alt=\"\" width=\"300\" height=\"90\" class=\"alignnone size-medium wp-image-7177\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/12\/biofilms-and-C-type-lectins_pseudomonas-aeruginosa-300x90.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/12\/biofilms-and-C-type-lectins_pseudomonas-aeruginosa-600x180.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/12\/biofilms-and-C-type-lectins_pseudomonas-aeruginosa-1024x307.png 1024w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/12\/biofilms-and-C-type-lectins_pseudomonas-aeruginosa-768x230.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/12\/biofilms-and-C-type-lectins_pseudomonas-aeruginosa.png 1284w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>School of Life Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK\u3089\u306e\u30b0\u30eb<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e7%b7%91%e8%86%bf%e8%8f%8c%ef%bc%88%e3%82%b7%e3%83%a5%e3%83%bc%e3%83%89%e3%83%a2%e3%83%8a%e3%82%b9%e3%83%bb%e3%82%a2%e3%83%ab%e3%82%ae%e3%83%8e%e3%83%bc%e3%82%b6%ef%bc%89%e3%81%ae%e6%85%a2%e6%80%a7\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-7176","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"School of Life Sciences, Faculty of Medicine and Health\" \/>\n\t<meta name=\"robots\" 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