{"id":6931,"date":"2021-11-26T10:11:09","date_gmt":"2021-11-26T01:11:09","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=6931"},"modified":"2021-11-26T11:35:43","modified_gmt":"2021-11-26T02:35:43","slug":"%e3%83%92%e3%83%88ips%e3%81%8b%e3%82%89%e5%88%86%e5%8c%96%e8%aa%98%e5%b0%8e%e3%81%97%e3%81%9f%e7%b3%b8%e7%90%83%e4%bd%93%e4%b8%8a%e7%9a%ae%e7%b4%b0%e8%83%9e%e3%81%b8%e3%81%aesars-cov-2%e3%81%ae","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e3%83%92%e3%83%88ips%e3%81%8b%e3%82%89%e5%88%86%e5%8c%96%e8%aa%98%e5%b0%8e%e3%81%97%e3%81%9f%e7%b3%b8%e7%90%83%e4%bd%93%e4%b8%8a%e7%9a%ae%e7%b4%b0%e8%83%9e%e3%81%b8%e3%81%aesars-cov-2%e3%81%ae\/","title":{"rendered":"\u30d2\u30c8iPS\u304b\u3089\u5206\u5316\u8a98\u5c0e\u3057\u305f\u7cf8\u7403\u4f53\u4e0a\u76ae\u7d30\u80de\u3078\u306eSARS-CoV-2\u306e\u611f\u67d3\u306b\u306f\u3001ACE2\u4ee5\u5916\u306bBSG\/CD147\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b"},"content":{"rendered":"<p>Department of Biomedical Engineering, 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href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34816259\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34816259\/<\/a><\/p>\n<p>\u30d2\u30c8\u306eiPS\u7d30\u80de\u304b\u3089\u5206\u5316\u8a98\u5c0e\u3057\u305f\u7cf8\u7403\u4f53\u4e0a\u76ae\u7d30\u80de\u306b\u306f\u3001SARS-CoV-2\u306e\u7d50\u5408\u3084\u30a6\u30a4\u30eb\u30b9\u306e\u7d30\u80de\u819c\u878d\u5408\u306a\u3069\u306b\u95a2\u308f\u308b\u3068\u601d\u308f\u308c\u308b\u53d7\u5bb9\u4f53\u3084\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u767a\u73fe\u3057\u3066\u3044\u307e\u3059\uff08\u4f8b\u3048\u3070\u3001ACE2\u3001BSG\/CD147\u3001TMPRSS2\u3001CTSL\u3001CD33\u3001DC-SIGN\/CD209\u3001SIGLEC9\u3001SIGLEC10\u3001ACTR3\u3001CLEC10A \u7b49\u3067\u3059\uff09\u3002 Transmembrane Serine Protease 2 (TMPRSS2)\u3001cathepsin L (CTSL) 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src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/11\/iPS-Podocyte_SARS-CoV-2-300x156.png\" alt=\"\" width=\"300\" height=\"156\" class=\"alignnone size-medium wp-image-6934\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/11\/iPS-Podocyte_SARS-CoV-2-300x156.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/11\/iPS-Podocyte_SARS-CoV-2-600x312.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/11\/iPS-Podocyte_SARS-CoV-2-768x399.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/11\/iPS-Podocyte_SARS-CoV-2.png 951w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u305d\u308c\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u30d2\u30c8iPS\u7531\u6765\u306e\u7cf8\u7403\u4f53\u4e0a\u76ae\u7d30\u80de\u306f\u3001MOI=0.01\uff5e1\u3068\u3044\u3046\u30a6\u30a4\u30eb\u30b9\u6570\u306e\u5c11\u306a\u3055\u3067\u3001SARS-CoV-2\u304c\u611f\u67d3\u3057\u3001\u3057\u304b\u3082\u3001\u9a5a\u304f\u3079\u304d\u3053\u3068\u306b\u3001Calu-3\u7d30\u80de\u3084Caco-2\u7d30\u80de\u3088\u308a\u3082\u3001\u30d2\u30c8iPS\u7531\u6765\u7cf8\u7403\u4f53\u4e0a\u76ae\u7d30\u80de\u306e\u65b9\u304c\u9855\u8457\u306b\u591a\u304f\u306e\u30a6\u30a4\u30eb\u30b9\u304c\u611f\u67d3\u3057\u3066\u3044\u307e\u3057\u305f\uff08p-value < 0.0001\uff09\u3002ACE2\u6297\u4f53\u3084BSG\/CD147\u6297\u4f53\u3067\u524d\u51e6\u7406\u3092\u884c\u3046\u3068\uff080.1 \u00b5g\/ml\uff09\u3001\u9855\u8457\u306b\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u304c\u6e1b\u5c11\u3057\uff08p-value < 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class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-6931","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Department of Biomedical Engineering, Pratt School of E\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.emukk.com\/WP\/%e3%83%92%e3%83%88ips%e3%81%8b%e3%82%89%e5%88%86%e5%8c%96%e8%aa%98%e5%b0%8e%e3%81%97%e3%81%9f%e7%b3%b8%e7%90%83%e4%bd%93%e4%b8%8a%e7%9a%ae%e7%b4%b0%e8%83%9e%e3%81%b8%e3%81%aesars-cov-2%e3%81%ae\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 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