{"id":656,"date":"2020-09-30T15:31:25","date_gmt":"2020-09-30T06:31:25","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=656"},"modified":"2021-07-22T00:05:51","modified_gmt":"2021-07-21T15:05:51","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sras-cov-2%ef%bc%89%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e4%b8%80%e6%8f%90%e6%a1%88","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sras-cov-2%ef%bc%89%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e4%b8%80%e6%8f%90%e6%a1%88\/","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306e\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u4e00\u63d0\u6848\uff1aNK\u7d30\u80de\u306e\u5f79\u5272\u306b\u3064\u3044\u3066"},"content":{"rendered":"<p>\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306b\u304a\u3044\u3066\u3001NK\u7d30\u80de\u306f\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002University of Ferrara\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306e\u611f\u67d3\u306b\u304a\u3044\u3066\u3001NK\u7d30\u80de\u304c\u5982\u4f55\u306a\u308b\u632f\u308b\u821e\u3044\u3092\u3057\u3066\u3044\u308b\u304b\u306b\u3064\u3044\u3066\u7814\u7a76\u3057\u305f\u7d50\u679c\u3092\u3082\u3068\u306b\u3001\u6297-NKG2A\u6297\u4f53\u3092\u7528\u3044\u305f\u6cbb\u7642\u6cd5\u3092\u63d0\u6848\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32859121\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32859121\/<\/a><\/p>\n<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306eS\u30bf\u30f3\u30d1\u30af\u8cea\uff08Spike 1 Protein, Spike 2 Protein\u305d\u308c\u305e\u308c\uff09\u3092\u80ba\u4e0a\u76ae\u7d30\u80de\u306b\u611f\u67d3\u3055\u305b\u3001NK\u7d30\u80de\u3068\u5171\u57f9\u990a\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001GATA3\uff08\u8ee2\u5199\u56e0\u5b50\uff09\u3001HLA-E\uff08\u30d2\u30c8\u767d\u8840\u7403\u6297\u539f\u306eE\u30af\u30e9\u30b9\uff09\u3001NKG2A\/CD94\uff08NK\u7d30\u80de\u6291\u5236\u6027\u53d7\u5bb9\u4f53\uff09\u3001CD107a\uff08\u8131\u9846\u7c92\u30de\u30fc\u30ab\u30fc\uff1a\u7d30\u80de\u969c\u5bb3\u56e0\u5b50\u306e\u653e\u51fa\uff09\u3001\u305d\u3057\u3066IFN-\u03b3\u306e\u767a\u73fe\u72b6\u614b\u3092\u8abf\u3079\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u4e0b\u8a18\u306e\u3088\u3046\u306a\u767a\u73fe\u5909\u52d5\u304c\u8d77\u3053\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n<ol>\n<li>GATA3\u306e\u6602\u9032<\/li>\n<li>HLA-E\u306e\u6602\u9032<\/li>\n<li>NKG2A\/CD94\u306e\u6602\u9032<\/li>\n<li>CD107a\u306e\u6e1b\u5c11<\/li>\n<li>IFN-\u03b3\u306e\u6e1b\u5c11<\/li>\n<\/ol>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/09\/NK1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-737\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/09\/NK1-150x150.png\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/09\/NK1-150x150.png 150w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/09\/NK1-300x300.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/09\/NK1-100x100.png 100w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u3053\u308c\u3089\u306e\u5909\u5316\u306f\u3001S\u30bf\u30f3\u30d1\u30af\u8cea\u306eSP1\uff08Spike 1 Protein\uff09\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u3066\u3044\u307e\u3059\u3002SP1\u306e\u611f\u67d3\u306b\u3088\u3063\u3066\u3001\u8ee2\u5199\u56e0\u5b50\u3067\u3042\u308bGATA3\u304c\u6d3b\u6027\u5316\u3055\u308c\u3001SP1\u30da\u30d7\u30c1\u30c9\uff088mer\uff09\u304cHLA-E\u306b\u3088\u3063\u3066\u7d30\u80de\u8868\u9762\u306b\u63d0\u793a\u3055\u308c\u307e\u3059\u3002HLA-E\u3068NKG2A\/CD94\u304c\u7d50\u5408\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001NK\u7d30\u80de\u306b\u6291\u5236\u6027\u306e\u4fe1\u53f7\u304c\u5165\u308a\u307e\u3059\u3002\u540c\u6642\u306b\u7d30\u80de\u969c\u5bb3\u56e0\u5b50\u306e\u653e\u51fa\u3082\u6291\u5236\u3055\u308c\u3001IFN-\u03b3\u306e\u653e\u51fa\u3082\u6291\u5236\u3055\u308c\u3001\u30a6\u30a4\u30eb\u30b9\u6392\u9664\u306e\u514d\u75ab\u6a5f\u80fd\u304c\u5f31\u307e\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u5f93\u3063\u3066\u3001\u7d50\u8ad6\u3068\u3057\u3066\u3001\u611f\u67d3\u521d\u671f\u306b\u304a\u3044\u3066\u3001\u6297-NKG2A\u6297\u4f53\uff08monalizumab\uff09\u3092\u6295\u4e0e\u3059\u308b\u3053\u3068\u304c\u514d\u75ab\u6d3b\u6027\u3092\u5897\u5f37\u3059\u308b\u624b\u6bb5\u3068\u3057\u3066\u6709\u52b9\u3067\u306f\u306a\u3044\u304b\uff1f\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306b\u304a\u3044\u3066\u3001NK\u7d30\u80de\u306f\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002University of Ferrara\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306e\u611f\u67d3\u306b\u304a\u3044\u3066\u3001NK\u7d30\u80de\u304c\u5982\u4f55\u306a\u308b\u632f\u308b\u821e\u3044\u3092\u3057\u3066\u3044\u308b\u304b\u306b\u3064\u3044\u3066<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sras-cov-2%ef%bc%89%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e4%b8%80%e6%8f%90%e6%a1%88\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"image","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-656","post","type-post","status-publish","format-image","hentry","category-nature-ja","post_format-post-format-image"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306b\u304a\u3044\u3066\u3001NK\u7d30\u80de\u306f\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002University of Ferrara\u306e\u30b0\u30eb\u30fc\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" 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