{"id":6514,"date":"2021-10-16T09:52:44","date_gmt":"2021-10-16T00:52:44","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=6514"},"modified":"2021-10-16T16:16:31","modified_gmt":"2021-10-16T07:16:31","slug":"covid-19%e3%81%ab%e3%82%88%e3%82%8b%e8%85%8e%e6%a9%9f%e8%83%bd%e9%9a%9c%e5%ae%b3%e3%81%ab%e5%af%be%e3%81%97%e3%81%a6%e3%80%81ungal%e3%81%8c%e5%84%aa%e3%82%8c%e3%81%9f%e3%83%9e%e3%83%bc%e3%82%ab","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/covid-19%e3%81%ab%e3%82%88%e3%82%8b%e8%85%8e%e6%a9%9f%e8%83%bd%e9%9a%9c%e5%ae%b3%e3%81%ab%e5%af%be%e3%81%97%e3%81%a6%e3%80%81ungal%e3%81%8c%e5%84%aa%e3%82%8c%e3%81%9f%e3%83%9e%e3%83%bc%e3%82%ab\/","title":{"rendered":"COVID-19\u306b\u3088\u308b\u814e\u6a5f\u80fd\u969c\u5bb3\u306b\u5bfe\u3057\u3066\u3001uNGAL\u304c\u512a\u308c\u305f\u30de\u30fc\u30ab\u30fc\u3068\u306a\u308b"},"content":{"rendered":"<p>Department of Medicine, Columbia University, New York, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u306b\u304a\u3044\u3066\u3001\u5c3f\u4e2d\u597d\u4e2d\u7403\u30bc\u30e9\u30c1\u30ca\u30fc\u30bc\u7d50\u5408\u6027\u30ea\u30dd\u30ab\u30ea\u30f3\uff08uNGAL\uff09\u304c\u3001\u7d44\u7e54\u75c5\u7406\u5b66\u7684\u640d\u50b7\uff08AKI\uff09\u3001\u814e\u6a5f\u80fd\u969c\u5bb3\uff08AKI\uff09\u3001\u305d\u3057\u3066COVID-19\u60a3\u8005\u306e\u91cd\u75c7\u5ea6\u3068\u5b9a\u91cf\u7684\u306b\u76f8\u95a2\u3057\u3066\u3044\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8497954\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8497954\/<\/a><\/p>\n<p>\u6ce8\u610f\u3059\u3079\u304d\u306f\u3001COVID-19\u306e\u60a3\u8005\u306f\u30012.6\u500dAKI\u3092\u767a\u75c7\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304f\uff0835.2% vs. 13.6%, P\uff1c0.0001\uff09\u30013.9\u500dAKI\u304c\u6301\u7d9a\u3057\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u9ad8\u304f\uff0817.5% vs. 4.5%, P\uff1c0.0001\uff09\u30011.8\u500d\u814e\u6a5f\u80fd\u969c\u5bb3\u304c\u91cd\u75c7\u5316\u3057\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u3042\u308b\uff08Acute Kidney Injury Network (AKIN) stages 2-3, 12.5% vs. 6.8%, P\uff1c0.01\uff09\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u3001\u814e\u6a5f\u80fd\u969c\u5bb3\u3068\u3044\u3046\u306e\u306f\u3001COVID-19\u611f\u67d3\u306b\u5171\u901a\u3059\u308b\u7279\u5fb4\u306a\u306e\u3067\u3059\u304c\u3001\u8840\u4e2d\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\uff08SCr\uff09\u306f\u3001\u3053\u306e\u3088\u3046\u306a\u814e\u6a5f\u80fd\u969c\u5bb3\u306b\u5bfe\u3057\u3066\u306f\u3042\u307e\u308a\u611f\u5ea6\u306e\u826f\u3044\u30de\u30fc\u30ab\u30fc\u3068\u306f\u8a00\u3048\u307e\u305b\u3093\u3002<\/p>\n<p>\u4f8b\u3048\u3070\u3001SCr\u306f\u3001\u8a3a\u65ad\u306e\u30ab\u30c3\u30c8\u30aa\u30d5\u5024\u306b\u9054\u3059\u308b\u307e\u3067\u5341\u5206\u306a\u6642\u9593\u3092\u304b\u3051\u3066\u84c4\u7a4d\u3055\u308c\u305f\u5f8c\u3001\u904e\u53bb\u306b\u9061\u3063\u3066\u814e\u6a5f\u80fd\u969c\u5bb3\u3092\u691c\u51fa\u3059\u308b\u3053\u3068\u3057\u304b\u3067\u304d\u307e\u305b\u3093\u3002 \u52a0\u3048\u3066\u3001\u9650\u5c40\u7684\u306a\u814e\u7d44\u7e54\u3078\u306e\u30c0\u30e1\u30fc\u30b8\u3067\u306f\u3001SCr\u306b\u306f\u9855\u8457\u306a\u5f71\u97ff\u306f\u8d77\u3053\u3089\u306a\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002SCr\u306e\u5024\u304c\u4e0a\u6607\u3057\u305f\u3053\u3068\u304c\u9855\u8457\u306a\u5834\u5408\u3067\u3082\u3001\u5c3f\u7d30\u7ba1\u640d\u50b7\u306e\u8a3c\u62e0\u306f\u3001COVID-19\u306e\u60a3\u8005\u3067\u826f\u304f\u898b\u3089\u308c\u308b\u4e0b\u75e2\u306b\u3088\u3063\u3066\u5c3f\u306e\u91cf\u304c\u5c11\u306a\u304f\u306a\u3063\u3066\u3044\u308b\u3088\u3046\u306a\u5834\u5408\u3001\u6b20\u3051\u3066\u3044\u308b\u304b\u3082\u77e5\u308c\u307e\u305b\u3093\u3057\u3001SCr\u306e\u4e0a\u6607\u306f\u3001\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u7523\u751f\u3092\u4fc3\u3059COVID-19\u306b\u304a\u3051\u308b\u6a2a\u7d0b\u7b4b\u878d\u89e3\u75c7\u306e\u767a\u751f\u306b\u3088\u3063\u3066\u3082\u4e71\u3055\u308c\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n<p>\u305d\u3053\u3067\u3001\u8457\u8005\u3089\u306f\u3001uNGAL\u3068\u5c3f\u4e2dKIM-1 (uKIM-1) \u304c\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u4f7f\u7528\u3067\u304d\u306a\u3044\u304b\u306b\u3064\u3044\u3066\u3001\u30b3\u30ed\u30f3\u30d3\u30a2\u5927\u5b66\u306e\u6551\u6025\u79d1\u306b\u304a\u3051\u308b\u30cb\u30e5\u30fc\u30e8\u30fc\u30af\u306eCOVID-19\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u306e\u30d4\u30fc\u30af\uff08March-April 2020\uff09\u6642\u306e444\u540d\u306e\u30b3\u30db\u30fc\u30c8\u30c7\u30fc\u30bf\u3092\u4f7f\u7528\u3057\u3066\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u7d50\u679c\u3068\u3057\u3066\u3001uKIM-1\u3067\u306f\u306a\u304f\u3001uNGAL\u304c\u814e\u6a5f\u80fd\u969c\u5bb3\u306e\u91cd\u75c7\u5ea6\u3068\u975e\u5e38\u306b\u826f\u304f\u76f8\u95a2\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\uff08\u4e0b\u56f3\u53c2\u7167\uff09\u3002uNGAL\u306e\u30ec\u30d9\u30eb\u306f\u3001AKIN\u306e\u30b9\u30c6\u30fc\u30b8\u3068\u5171\u306b\u968e\u6bb5\u72b6\u306b\u4e0a\u6607\u3057\u3066\u3044\u307e\u3059\uff08P\uff1c0.0001\uff09\u3002\u540c\u69d8\u306buRGAL\u306eROC\u30ab\u30fc\u30d6\u3082AKIN\u306e\u30b9\u30c6\u30fc\u30b8\u3068\u5171\u306b\u4e0a\u6607\u3057\u3066\u3044\u307e\u3059\uff080.70-0.93\uff09\u3002uNGAL\u306f\u3001\u30ab\u30c3\u30c8\u30aa\u30d5\u5024\u309215ng\/mL\u3068\u3057\u305f\u6642\u306b\u3001\u611f\u5ea6\uff1d80%\u3001\u7279\u7570\u5ea6\uff1d75% 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\/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Department of Medicine, Columbia University, New York, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u306b\u304a\u3044\u3066\u3001\u5c3f\u4e2d\u597d\u4e2d\u7403\u30bc\u30e9\u30c1\u30ca\u30fc\u30bc\u7d50\u5408\u6027\u30ea\u30dd\u30ab\u30ea\u30f3\uff08uNGAL\uff09\u304c\u3001\u7d44\u7e54\u75c5<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/covid-19%e3%81%ab%e3%82%88%e3%82%8b%e8%85%8e%e6%a9%9f%e8%83%bd%e9%9a%9c%e5%ae%b3%e3%81%ab%e5%af%be%e3%81%97%e3%81%a6%e3%80%81ungal%e3%81%8c%e5%84%aa%e3%82%8c%e3%81%9f%e3%83%9e%e3%83%bc%e3%82%ab\/\" 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