{"id":6301,"date":"2021-10-01T07:52:58","date_gmt":"2021-09-30T22:52:58","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=6301"},"modified":"2021-10-01T07:52:58","modified_gmt":"2021-09-30T22:52:58","slug":"%e5%85%8d%e7%96%ab%e7%b4%b0%e8%83%9e%e3%81%b8%e3%81%aesars-cov-2%e6%84%9f%e6%9f%93%e3%82%92%e5%bc%95%e3%81%8d%e8%b5%b7%e3%81%93%e3%81%99%e6%8a%97%e4%bd%93%e4%be%9d%e5%ad%98%e6%80%a7%e6%84%9f%e6%9f%93","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e5%85%8d%e7%96%ab%e7%b4%b0%e8%83%9e%e3%81%b8%e3%81%aesars-cov-2%e6%84%9f%e6%9f%93%e3%82%92%e5%bc%95%e3%81%8d%e8%b5%b7%e3%81%93%e3%81%99%e6%8a%97%e4%bd%93%e4%be%9d%e5%ad%98%e6%80%a7%e6%84%9f%e6%9f%93\/","title":{"rendered":"\u514d\u75ab\u7d30\u80de\u3078\u306eSARS-CoV-2\u611f\u67d3\u3092\u5f15\u304d\u8d77\u3053\u3059\u6297\u4f53\u4f9d\u5b58\u6027\u611f\u67d3\u5897\u5f37\uff08ADE\uff09\u306f\u78ba\u304b\u306b\u5b58\u5728\u3057\u3066\u3044\u308b"},"content":{"rendered":"<p>The Institute of Medical Science, The University of Tokyo\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001SARS-CoV-2\u306e\u6297\u4f53\u4f9d\u5b58\u6027\u611f\u67d3\u5897\u5f37\uff08ADE\uff09\u306f\u30ea\u30a2\u30eb\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/journals.asm.org\/doi\/10.1128\/mBio.01987-21\">https:\/\/journals.asm.org\/doi\/10.1128\/mBio.01987-21<\/a><\/p>\n<p>\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306f\u3001\u4e3b\u306b\u306f\u3069\u3093\u306a\u7d30\u80de\u3067\u3042\u3063\u3066\u3082\u7279\u5b9a\u306e\u53d7\u5bb9\u4f53\u3092\u7d4c\u7531\u3057\u3066\u8d77\u3053\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u6297\u4f53\u4f9d\u5b58\u6027\u611f\u67d3\u5897\u5f37\uff08ADE\uff09\u306f\u3001\u305d\u306e\u4ee3\u66ff\u611f\u67d3\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3042\u308a\u3001\u6297\u4f53\u3068IgG\u53d7\u5bb9\u4f53\uff08Fc\u03b3Rs\uff09\u304c\u611f\u67d3\u306b\u4ecb\u5728\u3057\u3066\u3044\u307e\u3059\u3002 <\/p>\n<p>\u8457\u8005\u3089\u306f\u3001\u30d2\u30c8\u306eIgG\u53d7\u5bb9\u4f53 Fc\u03b3Rs\uff08Fc\u03b3RIA\u3001Fc\u03b3RIIA\u3001Fc\u03b3RIIIA\uff09\u3084\u30d2\u30c8\u306eACE2\uff08SARS-CoV-2\u306e\u4e3b\u305f\u308b\u611f\u67d3\u53d7\u5bb9\u4f53\uff09\u3092\u767a\u73fe\u3055\u305b\u305fBHK\u7d30\u80de\u3092\u7528\u610f\u3057\u307e\u3057\u305f\u3002\u56e0\u307f\u306b\u3001\u91ce\u751f\u578b\u306eBHK\u7d30\u80de\u306b\u306f\u3001ACE2\u306f\u767a\u73fe\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u305d\u306eBHK\u7d30\u80de\u3092\u3001\u30eb\u30b7\u30d5\u30a7\u30e9\u30fc\u30bc\u3092\u767a\u73fe\u3055\u305b\u305f\u6c34\u6ce1\u53e3\u708e\u30a6\u30a4\u30eb\u30b9\uff08VSV\uff09\u304b\u3089VSV\u306e\u907a\u4f1d\u5b50\u3092\u9664\u304d\u3001\u4ee3\u308f\u308a\u306bSARS-CoV-2 Spike\u306b\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3057\u305f\u7591\u4f3c\u30a6\u30a4\u30eb\u30b9\uff08VSV-SARS2-S\uff09\u3067\u611f\u67d3\u3055\u305b\u307e\u3057\u305f\u3002<\/p>\n<p>BHK-hACE2 \u7d30\u80de\u306fVSV-SARS2-S\u306b\u611f\u67d3\u3057\u307e\u3057\u305f\u304c\u3001BHK-Fc\u03b3RIA\u3001BHK-Fc\u03b3RIIA\u3001BHK-Fc\u03b3RIIIA \u7d30\u80de\u3089\u306fACE2\u306e\u767a\u73fe\u3092\u6b20\u304f\u70ba\u304b\u3001\u611f\u67d3\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001COVID-19\u306e\u56de\u5fa9\u671f\u60a3\u8005\u306e\u8840\u6f3f\u3092VSV-SARS2-S\u3068\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30c8\u3055\u305b\u308b\u3068\u3001\uff12\u7a2e\u306eIgG\u53d7\u5bb9\u4f53\uff08Fc\u03b3RIIA \u3068 Fc\u03b3RIIIA\uff09\u304c\u6297\u4f53\u4f9d\u5b58\u6027\u611f\u67d3\u5897\u5f37\uff08ADE\uff09\u3092ACE2\u306e\u5b58\u5728\u4e0b\u3067\u5f15\u304d\u8d77\u3053\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u305d\u3057\u3066\u307e\u305f\u3001SARS-CoV-2\u611f\u67d3\u304c\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u304a\u3044\u3066\u3082\u56de\u5fa9\u671f\u60a3\u8005\u306e\u8840\u6f3f\u3067\u5897\u5f37\u3055\u308c\u308b\u3053\u3068\u3082\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/ADE_SARS-CoV-2.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/ADE_SARS-CoV-2-300x165.png\" alt=\"\" width=\"300\" height=\"165\" class=\"alignnone size-medium wp-image-6305\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/ADE_SARS-CoV-2-300x165.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/ADE_SARS-CoV-2.png 562w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Institute of Medical Science, The University of Tokyo\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001SARS-CoV-2\u306e\u6297\u4f53\u4f9d\u5b58\u6027\u611f\u67d3\u5897\u5f37\uff08ADE\uff09\u306f\u30ea\u30a2\u30eb\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002 <\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e5%85%8d%e7%96%ab%e7%b4%b0%e8%83%9e%e3%81%b8%e3%81%aesars-cov-2%e6%84%9f%e6%9f%93%e3%82%92%e5%bc%95%e3%81%8d%e8%b5%b7%e3%81%93%e3%81%99%e6%8a%97%e4%bd%93%e4%be%9d%e5%ad%98%e6%80%a7%e6%84%9f%e6%9f%93\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-6301","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.1.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"The Institute of Medical Science, The University of Tok\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.emukk.com\/WP\/%e5%85%8d%e7%96%ab%e7%b4%b0%e8%83%9e%e3%81%b8%e3%81%aesars-cov-2%e6%84%9f%e6%9f%93%e3%82%92%e5%bc%95%e3%81%8d%e8%b5%b7%e3%81%93%e3%81%99%e6%8a%97%e4%bd%93%e4%be%9d%e5%ad%98%e6%80%a7%e6%84%9f%e6%9f%93\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO 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