{"id":6170,"date":"2021-09-22T11:13:35","date_gmt":"2021-09-22T02:13:35","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=6170"},"modified":"2021-09-22T13:48:33","modified_gmt":"2021-09-22T04:48:33","slug":"nk%e7%b4%b0%e8%83%9e%e8%a1%a8%e9%9d%a2%e3%81%8b%e3%82%89siglec-7%e3%82%92%e5%8f%96%e3%82%8a%e9%99%a4%e3%81%8f%e3%81%93%e3%81%a8%e3%81%a7%e3%80%81%e8%85%ab%e7%98%8d%e7%b4%b0%e8%83%9e%e3%81%ab%e5%af%be","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/nk%e7%b4%b0%e8%83%9e%e8%a1%a8%e9%9d%a2%e3%81%8b%e3%82%89siglec-7%e3%82%92%e5%8f%96%e3%82%8a%e9%99%a4%e3%81%8f%e3%81%93%e3%81%a8%e3%81%a7%e3%80%81%e8%85%ab%e7%98%8d%e7%b4%b0%e8%83%9e%e3%81%ab%e5%af%be\/","title":{"rendered":"NK\u7d30\u80de\u8868\u9762\u304b\u3089Siglec-7\u3092\u53d6\u308a\u9664\u304f\u3053\u3068\u3067\u3001\u816b\u760d\u7d30\u80de\u306b\u5bfe\u3059\u308b\u514d\u75ab\u6cbb\u7642\u306e\u52b9\u679c\u3092\u6539\u5584\u3055\u305b\u308b"},"content":{"rendered":"<p>Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, China\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u816b\u760d\u7d30\u80de\u3078\u306e\u514d\u75ab\u6cbb\u7642\u306e\u52b9\u679c\u3092\u6539\u5584\u3059\u308b\u305f\u3081\u306b\u3001NK\u7d30\u80de\u8868\u9762\u306eSiglec-7\u306e\u767a\u73fe\u3092\u9175\u7d20\u53cd\u5fdc\u7684\u306b\u5909\u5316\u3055\u305b\u308b\u65b9\u6cd5\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8393205\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8393205\/<\/a><\/p>\n<p>\u30b7\u30a2\u30eb\u9178\u306b\u30a2\u30d5\u30a3\u30cb\u30c6\u30a3\u30fc\u3092\u6301\u3064\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u69d8\u306e\u30ec\u30af\u30c1\u30f3\uff08\u30b7\u30b0\u30ec\u30c3\u30af\uff1aSiglec-7\u306a\u3069\uff09\u304c\u514d\u75ab\u7d30\u80de\uff08NK\u7d30\u80de\u3084T\u7d30\u80de\u3089\uff09\u306b\u5b58\u5728\u3057\u3001\u305d\u308c\u304c\u7cd6\u9396\u306b\u95a2\u9023\u3057\u305f\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u5206\u5b50\u3068\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002 <\/p>\n<p>\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u816b\u760d\u7d30\u80de\u306e\u514d\u75ab\u6cbb\u7642\u306e\u6291\u5236\u306b\u95a2\u3057\u3066\u3001\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u8a73\u7d30\u306b\u5206\u304b\u3063\u3066\u3044\u308b\u3068\u306f\u8a00\u3048\u307e\u305b\u3093\u3002<br \/>\n\u8457\u8005\u3089\u306f\u3001NK\u7d30\u80de\u304c\u816b\u760d\u7d30\u80de\u306b\u63a5\u89e6\u3059\u308b\u3053\u3068\u304c\u3001Siglec-7\u306b\u5bfe\u3059\u308b\u30ea\u30ac\u30f3\u30c9\uff08\u30b7\u30a2\u30eb\u9178\u4fee\u98fe\u3092\u4f34\u3046\u7cd6\u9396\uff09\u306e\u816b\u760d\u7d30\u80de\u306b\u304a\u3051\u308b\u84c4\u7a4d\u306e\u30c8\u30ea\u30ac\u30fc\u3068\u306a\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002NK\u7d30\u80de\u3068\u816b\u760d\u7d30\u80de\u304c\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u3068\u30012\u6642\u9593\u4ee5\u5185\u306b\u816b\u760d\u7d30\u80de\u306e\u30b7\u30a2\u30eb\u9178\u4fee\u98fe\u3092\u4f34\u3046\u7cd6\u9396\u306e\u767a\u73fe\u304c\u6025\u901f\u306b\u767a\u751f\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001NK\u7d30\u80de\u304b\u3089\u30bf\u30fc\u30b2\u30c3\u30c8\u306e\u816b\u760d\u7d30\u80de\u306b\u30b7\u30a2\u30eb\u9178\u4fee\u98fe\u3092\u4f34\u3046\u7cd6\u9396\u304c\u8ee2\u79fb\u3055\u308c\u308b\u3053\u3068\u3068\u3001\u816b\u760d\u7d30\u80de\u3067\u306e\u65b0\u305f\u306a\u30b7\u30a2\u30eb\u9178\u4fee\u98fe\u3092\u4f34\u3046\u7cd6\u9396\u306e\u5408\u6210\u304c\u9032\u3080\u3053\u3068\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002<\/p>\n<p>\u764c\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u514d\u75ab\u7642\u6cd5\u306e\u6709\u671b\u306a\u65b9\u6cd5\u3068\u3057\u3066\u3001\u62e1\u5f35\u3055\u308c\u305f\u540c\u7a2eNK\u7d30\u80de\u306e\u79fb\u690d\u3068\u3044\u3046\u65b9\u6cd5\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u8457\u8005\u3089\u306f\u3001\u9175\u7d20\u7684\u306bcytidine-5&#8242;-monophospho (CMP)-<sup>FTMC<\/sup>Neu5Ac\u3068ST6Gal\u3092\u7528\u3044\u308b\u3053\u3068\u3067NK\u7d30\u80de\u8868\u9762\u4e0a\u306bSiglec-7\u306b\u5bfe\u3057\u3066\u9ad8\u3044\u30a2\u30d5\u30a3\u30cb\u30c6\u30a3\u30fc\u3092\u6301\u3064\u30b7\u30a2\u30eb\u9178\u4fee\u98fe\u3092\u4f34\u3046\u7cd6\u9396\u3092\u767a\u73fe\u3055\u305b\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001NK\u7d30\u80de\u8868\u9762\u304c\u30bf\u30fc\u30b2\u30c3\u30c8\u306e\u816b\u760d\u7d30\u80de\u306b\u3088\u3063\u3066\u6d3b\u6027\u5316\u3055\u308c\u308b\u6642\u306b\u3001Siglec-7\u304c\u57f9\u990a\u4e0a\u6e05\u4e2d\u306b\u30ea\u30ea\u30fc\u30b9\u3055\u308c\u3001\u7d50\u679c\u3068\u3057\u3066NK\u7d30\u80de\u306e\u30a8\u30d5\u30a7\u30af\u30bf\u30fc\u6a5f\u80fd\u304c\u5897\u5f37\u3055\u308c\u514d\u75ab\u6cbb\u7642\u304c\u52b9\u679c\u7684\u306b\u884c\u3048\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/release-of-Siglec-7_NK-therapeutics.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/release-of-Siglec-7_NK-therapeutics-300x92.png\" alt=\"\" width=\"300\" height=\"92\" class=\"alignnone size-medium wp-image-6174\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/release-of-Siglec-7_NK-therapeutics-300x92.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/release-of-Siglec-7_NK-therapeutics-600x184.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/release-of-Siglec-7_NK-therapeutics-1024x315.png 1024w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/release-of-Siglec-7_NK-therapeutics-768x236.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/09\/release-of-Siglec-7_NK-therapeutics.png 1146w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, China\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u816b\u760d\u7d30\u80de\u3078\u306e\u514d\u75ab\u6cbb\u7642\u306e<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/nk%e7%b4%b0%e8%83%9e%e8%a1%a8%e9%9d%a2%e3%81%8b%e3%82%89siglec-7%e3%82%92%e5%8f%96%e3%82%8a%e9%99%a4%e3%81%8f%e3%81%93%e3%81%a8%e3%81%a7%e3%80%81%e8%85%ab%e7%98%8d%e7%b4%b0%e8%83%9e%e3%81%ab%e5%af%be\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-6170","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6170","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=6170"}],"version-history":[{"count":12,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6170\/revisions"}],"predecessor-version":[{"id":6185,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6170\/revisions\/6185"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=6170"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=6170"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=6170"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}