{"id":6068,"date":"2021-09-09T18:07:49","date_gmt":"2021-09-09T09:07:49","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=6068"},"modified":"2021-09-09T18:12:15","modified_gmt":"2021-09-09T09:12:15","slug":"r-type-lectin-perinereis-nuntia-lectin-pnl-from-marine-annelids","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/r-type-lectin-perinereis-nuntia-lectin-pnl-from-marine-annelids\/","title":{"rendered":"R-type lectin, Perinereis nuntia lectin (PnL),  from Marine Annelids"},"content":{"rendered":"<p>A group from University of Chittagong, Bangladesh (containing this blog admin), etc. has reported about R-type lectin, Perinereis nuntia lectin (PnL), isolated from Marine Annelids.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8399747\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8399747\/<\/a><\/p>\n<p>Previously, authors isolated PnL, a d-galactose-binding lectin of the R-type lectin family from Perinereis sp. <\/p>\n<p>R-type lectins are derived from the ricin B-chain, a protein toxin consisting of AB subunits, in castor bean seeds. They usually have the three-leaf clover-like \u03b2-trefoil fold with Gln-X-Trp (Q-X-W) sequences in each subdomain. Why annelids have R-type lectins, and what physiological functions R-type lectins in annelids have are still uinclear. It would be the first step to identify locations where RnL is expressed.<\/p>\n<p>Overall, PnL was found in extracellular locations after secretion from specific cells at the epidermis, setae, oblique muscle, acicula, nerve cord, and nephridium.<br \/>\nInterestingly, the localization pattern of the Gal\/GalNAc-containing glycans was found to be almost identical to the distribution of PnL.<\/p>\n<p>This co-localization is so interesting for blog admin, because the phytotoxin ricin is galactose-specific and clearly targets animal cells. What PnL is really doing?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from University of Chittagong, Bangladesh (containing this blog admin), etc. has reported about R-type<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/r-type-lectin-perinereis-nuntia-lectin-pnl-from-marine-annelids\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-6068","post","type-post","status-publish","format-standard","hentry","category-nature-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6068","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=6068"}],"version-history":[{"count":4,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6068\/revisions"}],"predecessor-version":[{"id":6072,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6068\/revisions\/6072"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=6068"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=6068"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=6068"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}