{"id":6032,"date":"2021-09-06T12:17:58","date_gmt":"2021-09-06T03:17:58","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=6032"},"modified":"2021-09-06T12:46:34","modified_gmt":"2021-09-06T03:46:34","slug":"%e6%8a%97%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e6%b4%bb%e6%80%a7%e3%82%92%e7%a4%ba%e3%81%99grft%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%e3%81%a8%e7%a1%ab%e9%85%b8%e5%8c%96%e5%a4%9a%e7%b3%96%e9%a1%9e","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%8a%97%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e6%b4%bb%e6%80%a7%e3%82%92%e7%a4%ba%e3%81%99grft%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%e3%81%a8%e7%a1%ab%e9%85%b8%e5%8c%96%e5%a4%9a%e7%b3%96%e9%a1%9e\/","title":{"rendered":"\u6297\u30a6\u30a4\u30eb\u30b9\u6d3b\u6027\u3092\u793a\u3059GRFT\u30ec\u30af\u30c1\u30f3\u3068\u786b\u9178\u5316\u591a\u7cd6\u985e\u3067\u3042\u308b\u30ab\u30e9\u30ae\u30fc\u30ca\u30f3\u3092\u6df7\u5408\u3057\u3066\u4f7f\u7528\u3059\u308b\u3068SARS-CoV-2\u306b\u5bfe\u3059\u308b\u6297\u30a6\u30a4\u30eb\u30b9\u6d3b\u6027\u304c\u5927\u5e45\u306b\u5f37\u5316\u3055\u308c\u308b"},"content":{"rendered":"

The City University of New York, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001GRFT\u30ec\u30af\u30c1\u30f3\u3068\u30ab\u30e9\u30ae\u30fc\u30ca\u30f3\u3092\u6df7\u5408\u3057\u3066\u4f7f\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u5176\u3005\u3092\u5358\u72ec\u3067\u7528\u3044\u308b\u5834\u5408\u306b\u6bd4\u3079\u3066\u3001SARS-CoV-2\u306b\u5bfe\u3059\u308b\u6297\u30a6\u30a4\u30eb\u30b9\u6d3b\u6027\u3092\u5927\u304d\u304f\u9ad8\u3081\u308b\u3053\u3068\u304c\u51fa\u6765\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002
\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8400000\/<\/a><\/p>\n

GRFT \u306f121\u500b\u306e\u30a2\u30df\u30ce\u9178\u914d\u5217\u304b\u3089\u306a\u308b\u30db\u30e2\u4e8c\u91cf\u4f53\u306e\u30ec\u30af\u30c1\u30f3\u3067\u3042\u308a\u3001high mannose\u306b\u9ad8\u3044\u30a2\u30d5\u30a3\u30cb\u30c6\u30a3\u2015\u3092\u793a\u3057\u307e\u3059\u3002High mannose\u69cb\u9020\u306f\u3001\u3057\u3070\u3057\u3070\u30a6\u30a4\u30eb\u30b9\u306e\u30b9\u30d1\u30a4\u30af\u306b\u5b58\u5728\u3059\u308b\u69cb\u9020\u3067\u3042\u308a\u3001HIV\u3001HSV\u3001HCV\u3001ebola\u3001\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306a\u3069\u306b\u898b\u3089\u308c\u308b\u3082\u306e\u3067\u3059\u3002GRFT\u306f\u3001pM\u306e\u6fc3\u5ea6\u3067HIV\u3092in vitro\u3067\u963b\u5bb3\u51fa\u6765\u308b\u3053\u3068\u304b\u3089\u3001GRFT\u306f\u3001HIV\u306e\u5897\u6b96\u3092\u963b\u5bb3\u3059\u308b\u6700\u3082\u512a\u308c\u305f\u963b\u5bb3\u5264\u306e\u4e00\u3064\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4e00\u65b9\u3001\u30ab\u30e9\u30ae\u30fc\u30ca\u30f3\u306f\u3001\u30ac\u30e9\u30af\u30c8\u30d4\u30e9\u30ce\u30fc\u30b9\u304b\u3089\u306a\u308b\uff12\u7cd6\u306e\u7e70\u308a\u8fd4\u3057\u69cb\u9020\u3092\u6301\u3064\u786b\u9178\u5316\u591a\u7cd6\u985e\u3067\u3042\u308a\u3001\uff13\u7a2e\u306e\u69cb\u9020\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\uff08\u03ba-Carrageenan (\u03ba-CG)\u3001\u03b9-Carrageenan (\u03b9-CG)\u3001\u03bb-Carrageenan (\u03bb-CG)\uff09\u3002\u30ab\u30e9\u30ae\u30fc\u30ca\u30f3\u3082\u6297\u30a6\u30a4\u30eb\u30b9\u6d3b\u6027\u3092\u6301\u3064\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u304a\u308a\u3001FDA\u306b\u304a\u3044\u3066\u305d\u306e\u5b89\u5168\u6027\u306f\u9ad8\u3044\u3068\u8a8d\u8b58\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

GRFT\u3001\u30ab\u30e9\u30ae\u30fc\u30ca\u30f3\u3001\u304a\u3088\u3073\u305d\u306e\u6df7\u5408\u7269\u306eSARS-CoV-2\u306b\u5bfe\u3059\u308b50\uff05\u52b9\u679c\u6fc3\u5ea6\uff08EC50<\/sub>\uff09\u3092\u4e0b\u8a18\u306b\u793a\u3057\u307e\u3059\u3002
\n——————————–
\nGRFT, 20.6\u00b5g\/mL
\n\u03b9-CG, 7.5\u00b5g\/mL
\n\u03bb-CG, 6.1\u00b5g\/mL
\n\u03b9-CG + GRFT (1:5), 0.2\u00b5g\/mL
\n\u03bb-CG + GRFT (1:5), 0.4\u00b5g\/mL
\n——————————–<\/p>\n

\u672c in vitro\u3067\u306e\u7591\u30a6\u30a4\u30eb\u30b9\u3092\u7528\u3044\u305f\u7d30\u80de\u611f\u67d3\u30a2\u30c3\u30bb\u30a4\u3067\u306e\u7d50\u679c\u3092\u78ba\u8a8d\u3059\u308b\u70ba\u3001\u4eca\u5f8c\u884c\u308f\u308c\u308b\u3067\u3042\u308d\u3046in vivo\u3067\u306e\u8a55\u4fa1\u7d50\u679c\u3092\u671f\u5f85\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

The City University of New York, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001GRFT\u30ec\u30af\u30c1\u30f3\u3068\u30ab\u30e9\u30ae\u30fc\u30ca\u30f3\u3092\u6df7\u5408\u3057\u3066\u4f7f\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u5176\u3005\u3092\u5358\u72ec\u3067\u7528\u3044\u308b\u5834\u5408\u306b\u6bd4\u3079\u3066\u3001SARS-CoV-2\u306b\u5bfe\u3059\u308b\u6297\u30a6\u30a4\u30eb\u30b9\u6d3b<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-6032","post","type-post","status-publish","format-standard","hentry","category-technology-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6032","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=6032"}],"version-history":[{"count":11,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6032\/revisions"}],"predecessor-version":[{"id":6045,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/6032\/revisions\/6045"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=6032"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=6032"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=6032"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}