{"id":5774,"date":"2021-08-17T10:16:05","date_gmt":"2021-08-17T01:16:05","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=5774"},"modified":"2021-08-22T08:27:53","modified_gmt":"2021-08-21T23:27:53","slug":"galectin-3-%e3%81%8c%e3%80%81covid-19%e9%87%8d%e7%97%87%e5%8c%96%e3%81%ae%e5%84%aa%e3%82%8c%e3%81%9f%e4%ba%88%e5%be%8c%e3%83%9e%e3%83%bc%e3%82%ab%e3%83%bc%e3%81%ab%e3%81%aa%e3%82%8a%e5%be%97%e3%82%8b","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/galectin-3-%e3%81%8c%e3%80%81covid-19%e9%87%8d%e7%97%87%e5%8c%96%e3%81%ae%e5%84%aa%e3%82%8c%e3%81%9f%e4%ba%88%e5%be%8c%e3%83%9e%e3%83%bc%e3%82%ab%e3%83%bc%e3%81%ab%e3%81%aa%e3%82%8a%e5%be%97%e3%82%8b\/","title":{"rendered":"Galectin-3 \u304c\u3001COVID-19\u91cd\u75c7\u5316\u306e\u512a\u308c\u305f\u4e88\u5f8c\u30de\u30fc\u30ab\u30fc\u306b\u306a\u308a\u5f97\u308b"},"content":{"rendered":"

University of Medicine \u201cAldo Moro\u201d, Bari, Italy\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u306e\u91cd\u75c7\u5316\u306b\u5bfe\u3057\u3066\u3001Galectin-3\u304c\u512a\u308c\u305f\u4e88\u5f8c\u30de\u30fc\u30ab\u30fc\u306b\u306a\u308a\u5f97\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8332745\/<\/a><\/p>\n

\u6050\u3089\u304f\u3001\u672c\u8ad6\u6587\u304cCOVID-19\u306e\u6025\u6027\u547c\u5438\u5668\u4e0d\u5168\uff08ARDS\uff09\u306b\u304a\u3051\u308b\u4e88\u5f8c\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u306eGalectin-3\u3092\u5831\u544a\u3059\u308b\u521d\u3081\u3066\u306e\u305d\u308c\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u8840\u4e2d\u306eGalectin-3\u6fc3\u5ea6\u304c\u9ad8\u3044\u60a3\u8005\u306f\u3001\u91cd\u5ea6\u306eARDS\u3092\u767a\u75c7\u3059\u308b\u5371\u967a\u6027\u304c\u9ad8\u304f\u3001\u4e88\u5f8c\u3082\u826f\u304f\u3042\u308a\u307e\u305b\u3093\u3002SARS-CoV-2\u611f\u67d3\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u60a3\u8005\u3067\u306f\u3001\u3044\u308f\u3086\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u30fb\u30b9\u30c8\u30fc\u30e0\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u6b7b\u306b\u81f3\u3063\u305f\u60a3\u8005\u3067\u306f\u3001\u5404\u7a2e\u306e\u8840\u4e2d\u708e\u75c7\u6027\u30de\u30fc\u30ab\u30fc\u306e\u5024\u304c\u9ad8\u304f\u306a\u3063\u3066\u304a\u308a\u3001\u305d\u308c\u3089\u306fCOVID-19\u306e\u91cd\u75c7\u5316\u3068\u826f\u304f\u76f8\u95a2\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u306b\u3082\u95a2\u308f\u3089\u305a\u3001\u8457\u8005\u3089\u306e\u591a\u5909\u91cf\u56de\u5e30\u5206\u6790\u30e2\u30c7\u30eb\u3067\u306f\u3001IL-5\u3001CRP\u3001\u305d\u3057\u3066Galectin-3\u306e\u307f\u304c\u7d71\u8a08\u7684\u306b\u610f\u5473\u306e\u3042\u308b\u7d50\u679c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002IL-6\u3068CRP\u306b\u3064\u3044\u3066\u306f\u3001\u3053\u308c\u306f\u9a5a\u304f\u3079\u304d\u3053\u3068\u3067\u306f\u306a\u304f\u3001\u65e2\u306b\u6570\u591a\u304f\u306e\u7814\u7a76\u3067\u3001IL-6\u3068CRP\u304cCOVID-19\u91cd\u75c7\u5316\u306e\u4e88\u5f8c\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002Galectin-3\u306b\u5bfe\u3057\u3066\u6ce8\u610f\u3092\u5411\u3051\u305f\u306e\u306f\u672c\u7814\u7a76\u304c\u521d\u3081\u3066\u3067\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u3001COVID-19\u91cd\u75c7\u5316\u3092\u4e88\u6e2c\u3059\u308bROC\u89e3\u6790\u306eAUC\u3067\u3001Galectin-3\u304c\u6700\u3082\u512a\u308c\u305f\u5024\u3092\u793a\u3057\u307e\u3057\u305f\u3002Galectin-3 cut-off\u5024=35.3ng\/mL\u306b\u3066\u3001AUC=0.75 (p = 0.001) \u3092\u5f97\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u5b9f\u969b\u3001\u8840\u4e2d\u306eGalectin-3\u6fc3\u5ea6\u304c35.3 ng\/ml \u3092\u8d85\u3048\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u306f\u3001\u91cd\u5ea6\u306eARDS\u3092\u767a\u75c7\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001ICU\u5165\u9662\u7387\u3084\u6b7b\u4ea1\u7387\u3082\u4e0a\u304c\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u306a\u304a\u3001\u672c\u7814\u7a76\u306e\u30b3\u30db\u30fc\u30c8\u30b5\u30a4\u30ba\u306f156\u540d\u306e\u60a3\u8005\u3067\u3057\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

University of Medicine \u201cAldo Moro\u201d, Bari, Italy\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u306e\u91cd\u75c7\u5316\u306b\u5bfe\u3057\u3066\u3001Galectin-3\u304c\u512a\u308c\u305f\u4e88\u5f8c\u30de\u30fc\u30ab\u30fc\u306b\u306a\u308a\u5f97\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002 htt<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642,42],"tags":[],"class_list":["post-5774","post","type-post","status-publish","format-standard","hentry","category-nature-ja","category-technology-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/5774","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=5774"}],"version-history":[{"count":8,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/5774\/revisions"}],"predecessor-version":[{"id":5801,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/5774\/revisions\/5801"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=5774"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=5774"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=5774"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}