{"id":5710,"date":"2021-08-13T16:06:44","date_gmt":"2021-08-13T07:06:44","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=5710"},"modified":"2021-08-22T08:30:23","modified_gmt":"2021-08-21T23:30:23","slug":"%e6%a8%b9%e7%8a%b6%e7%b4%b0%e8%83%9e%e3%81%aehla-ii%e3%81%ab%e6%8a%97%e5%8e%9f%e6%8f%90%e7%a4%ba%e3%81%95%e3%82%8c%e3%81%a6%e3%81%84%e3%82%8bsars-cov-2%e3%81%ae%e3%83%9a%e3%83%97%e3%83%81%e3%83%89","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%a8%b9%e7%8a%b6%e7%b4%b0%e8%83%9e%e3%81%aehla-ii%e3%81%ab%e6%8a%97%e5%8e%9f%e6%8f%90%e7%a4%ba%e3%81%95%e3%82%8c%e3%81%a6%e3%81%84%e3%82%8bsars-cov-2%e3%81%ae%e3%83%9a%e3%83%97%e3%83%81%e3%83%89\/","title":{"rendered":"\u6a39\u72b6\u7d30\u80de\u306eHLA-II\u306b\u6297\u539f\u63d0\u793a\u3055\u308c\u3066\u3044\u308bSARS-CoV-2\u306e\u30da\u30d7\u30c1\u30c9\u3067\u7cd6\u9396\u4fee\u98fe\u306f\u3069\u3046\u306a\u3063\u3066\u3044\u308b\u306e\u304b\uff1f"},"content":{"rendered":"<p>University of Oxford, UK\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6a39\u72b6\u7d30\u80de\u306eHLA-class II\u306b\u6297\u539f\u63d0\u793a\u3055\u308c\u308bSARS-CoV-2\u306e\u7cd6\u30da\u30d7\u30c1\u30c9\u306e\u30de\u30c3\u30d4\u30f3\u30b0\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8116342\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8116342\/<\/a><\/p>\n<p>\u30d6\u30ed\u30b0\u7ba1\u7406\u4eba\u306b\u3068\u3063\u3066\u306f\u3001\u6a39\u72b6\u7d30\u80de\u306eHLA-II\u306b\u6297\u539f\u63d0\u793a\u3055\u308c\u308b\u30da\u30d7\u30c1\u30c9\u304c\u3001SARS-CoV-2\u304c\u6a39\u72b6\u7d30\u80de\u306b\u8caa\u98df\u3055\u308c\u308b\u524d\u306b\u6301\u3063\u3066\u3044\u305f\u7cd6\u9396\u4fee\u98fe\u60c5\u5831\u3092\u305d\u306e\u307e\u307e\u7dad\u6301\u3057\u3066\u3044\u308b\u306e\u304b\u5426\u304b\u306b\u3064\u3044\u3066\u975e\u5e38\u306b\u8208\u5473\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>SARS-CoV-2\u306e\u30c8\u30fc\u30bf\u30eb22\u500b\u7b87\u6240\u306e\u7cd6\u9396\u4fee\u98fe\u306e\u4e2d\u3067\u3001HLA-II\u306b\u6297\u539f\u63d0\u793a\u3055\u308c\u305f\u7cd6\u30da\u30d7\u30c1\u30c9\u306f\u300114\u304b\u6240\u306e\u7cd6\u9396\u4fee\u98fe\u30b5\u30a4\u30c8\u3092\u542b\u3093\u3067\u3044\u308b\u3082\u306e\u304c\u898b\u3064\u304b\u308a\u307e\u3057\u305f\u3002HLA-II\u306b\u6297\u539f\u63d0\u793a\u3055\u308c\u305f\u7cd6\u30da\u30d7\u30c1\u30c9\u306f\u3001\u4e3b\u306b\u77ed\u9396\u306e\u30d1\u30a6\u30c1\u30de\u30f3\u30ce\u30fc\u30b9\u578b\u306eN-\u578b\u7cd6\u9396\u69cb\u9020\u3092\u6301\u3063\u3066\u304a\u308a\u3001\u30aa\u30ea\u30b8\u30ca\u30eb\u306eSARS-CoV-2\u304c\u6301\u3064\u30aa\u30ea\u30b4\u30de\u30f3\u30ce\u30fc\u30b9\u3001GlcNAc\u7d42\u7aef\u306e\u8907\u5408\u578bN-\u578b\u7cd6\u9396\u69cb\u9020\u3068\u306f\u7570\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u3053\u306e\u30d1\u30a6\u30c1\u30de\u30f3\u30ce\u30fc\u30b9\u578b\u306eN-\u578b\u7cd6\u9396\u306f\u3001Fucose\u4fee\u98fe\u306e\u60c5\u5831\u306f\u6301\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u3053\u306e\u4e8b\u306f\u3001\u6a39\u72b6\u7d30\u80de\u5185\u306e\u6297\u539f\u63d0\u793a\u306e\u30d7\u30ed\u30bb\u30b9\u306b\u304a\u3044\u3066\u3001\u7cd6\u9396\u304c\u5208\u308a\u8fbc\u307e\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3059\u3082\u306e\u3067\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/08\/HLA-II-bound-Spike-glycopeptides.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/08\/HLA-II-bound-Spike-glycopeptides-240x300.png\" alt=\"\" width=\"240\" height=\"300\" class=\"alignnone size-medium wp-image-5713\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/08\/HLA-II-bound-Spike-glycopeptides-240x300.png 240w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/08\/HLA-II-bound-Spike-glycopeptides-600x751.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/08\/HLA-II-bound-Spike-glycopeptides.png 697w\" sizes=\"auto, (max-width: 240px) 100vw, 240px\" \/><\/a><br \/>\n\u4e0a\u56f3\u306b\u304a\u3051\u308b\u30d2\u30fc\u30c8\u30de\u30c3\u30d7\u30ab\u30e9\u30fc\u306f\u5404\u3005\u306e\u7cd6\u9396\u69cb\u9020\u306e\u76f8\u5bfe\u7684\u306a\u983b\u5ea6\u3092\u793a\u3057\u3001\u8cea\u91cf\u5206\u6790\u30b9\u30da\u30af\u30c8\u30eb\u306b\u30de\u30c3\u30c1\u3057\u305f\u30da\u30d7\u30c1\u30c9\u6570\uff08\u9752\u8272\u30d0\u30fc\uff09\u3082\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of Oxford, UK\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6a39\u72b6\u7d30\u80de\u306eHLA-class II\u306b\u6297\u539f\u63d0\u793a\u3055\u308c\u308bSARS-CoV-2\u306e\u7cd6\u30da\u30d7\u30c1\u30c9\u306e\u30de\u30c3\u30d4\u30f3\u30b0\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/www.ncbi.n<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e6%a8%b9%e7%8a%b6%e7%b4%b0%e8%83%9e%e3%81%aehla-ii%e3%81%ab%e6%8a%97%e5%8e%9f%e6%8f%90%e7%a4%ba%e3%81%95%e3%82%8c%e3%81%a6%e3%81%84%e3%82%8bsars-cov-2%e3%81%ae%e3%83%9a%e3%83%97%e3%83%81%e3%83%89\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642,42],"tags":[],"class_list":["post-5710","post","type-post","status-publish","format-standard","hentry","category-nature-ja","category-technology-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"University of Oxford, UK\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6a39\u72b6\u7d30\u80de\u306eHLA-class II\u306b\u6297\u539f\u63d0\u793a\u3055\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta 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