{"id":5325,"date":"2021-07-23T11:25:07","date_gmt":"2021-07-23T02:25:07","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=5325"},"modified":"2021-07-23T18:07:59","modified_gmt":"2021-07-23T09:07:59","slug":"a-single-vaccination-is-sufficient-to-boost-immunity-to-high-levels-among-previously-infected-individuals","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/a-single-vaccination-is-sufficient-to-boost-immunity-to-high-levels-among-previously-infected-individuals\/","title":{"rendered":"A single vaccination is sufficient to boost immunity to high levels among previously infected individuals"},"content":{"rendered":"<p>A group from Northwestern University Feinberg School of Medicine, USA, etc. has reported on neutralizing antibody responses after one or two doses of COVID-19 mRNA vaccine in previously infected and uninfected individuals.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8276631\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8276631\/<\/a><\/p>\n<p>The following three groups were compared:<br \/>\n(1)<strong>COVID-19 group<\/strong>: previously recovered from a confirmed outpatient case of COVID-19,<br \/>\n(2)<strong>Seropositive group<\/strong>: seropositive for anti-SARS-CoV-2 receptor binding domain (RBD) IgG but no acute virus diagnostic test for COVID-19,<br \/>\n(3)<strong>Seronegative group<\/strong>: seronegative for prior SARS-CoV-2 infection prior to vaccination. <\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/vaccination-among-three-groups.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/vaccination-among-three-groups-300x195.png\" alt=\"\" width=\"300\" height=\"195\" class=\"alignnone size-medium wp-image-5323\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/vaccination-among-three-groups-300x195.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/vaccination-among-three-groups.png 498w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>The COVID-19 group had median% neutralization (22.2 vs. 4.4, p < 0.001) in comparison with the seropositive group. \nThe COVID-19 group had significantly higher median% neutralization (99.9 vs. 56.5, p < 0\u2022001) in comparison with the seropositive group. \nPost-dose 1 responses were higher for the seropositive group in comparison with the seronegative group, but %neutralization (56.5 vs. 38.2, p = 0\u202212) were not significantly different. \nThe COVID-19 group had higher post-dose 2 median% neutralization (99.9 vs. 98.5, p<0\u2022001) in comparison with the seropositive group. \nThe seropositive and seronegative groups did not differ significantly in post-dose 2 median% neutralization (98.5 vs. 97.9, p = 0.46).\n\nAs a result, a single dose is sufficient to boost immunity to high levels among previously infected individuals.\n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from Northwestern University Feinberg School of Medicine, USA, etc. has reported on neutralizing antib<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/a-single-vaccination-is-sufficient-to-boost-immunity-to-high-levels-among-previously-infected-individuals\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70,7],"tags":[],"class_list":["post-5325","post","type-post","status-publish","format-standard","hentry","category-nature-en","category-technology-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/5325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=5325"}],"version-history":[{"count":3,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/5325\/revisions"}],"predecessor-version":[{"id":5366,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/5325\/revisions\/5366"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=5325"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=5325"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=5325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}