{"id":5237,"date":"2021-07-22T17:13:17","date_gmt":"2021-07-22T08:13:17","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=5237"},"modified":"2021-07-22T17:13:17","modified_gmt":"2021-07-22T08:13:17","slug":"%e6%b5%b7%e8%97%bb%e3%81%8b%e3%82%89%e6%8a%bd%e5%87%ba%e3%81%95%e3%82%8c%e3%82%8b%e5%a4%9a%e7%b3%96%e9%a1%9e%e3%81%aesars-cov-2%e3%81%ae%e6%84%9f%e6%9f%93%e9%98%bb%e5%ae%b3%e5%8a%b9%e6%9e%9c%e3%81%ab","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%b5%b7%e8%97%bb%e3%81%8b%e3%82%89%e6%8a%bd%e5%87%ba%e3%81%95%e3%82%8c%e3%82%8b%e5%a4%9a%e7%b3%96%e9%a1%9e%e3%81%aesars-cov-2%e3%81%ae%e6%84%9f%e6%9f%93%e9%98%bb%e5%ae%b3%e5%8a%b9%e6%9e%9c%e3%81%ab\/","title":{"rendered":"\u6d77\u85fb\u304b\u3089\u62bd\u51fa\u3055\u308c\u308b\u591a\u7cd6\u985e\u306eSARS-CoV-2\u306e\u611f\u67d3\u963b\u5bb3\u52b9\u679c\u306b\u3064\u3044\u3066"},"content":{"rendered":"<p>Marine Biotechnology Research Center, Korea\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6d77\u85fb\u304b\u3089\u62bd\u51fa\u3057\u305f\u591a\u7cd6\u985e\u306eSARS-CoV-2\u306e\u611f\u67d3\u963b\u5bb3\u52b9\u679c\u3068\u7d30\u80de\u6bd2\u6027\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8071526\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8071526\/<\/a><\/p>\n<p>\u6d77\u85fb\u985e\u306f\u3001\u975e\u5e38\u306b\u512a\u308c\u305f\u751f\u85ac\u30bd\u30fc\u30b9\u3067\u3042\u308a\u3001\u591a\u7cd6\u985e\u3001\u98df\u7269\u7e4a\u7dad\u3001\u30a2\u30df\u30ce\u9178\u3001\u8102\u80aa\u9178\u3001\u5929\u7136\u8272\u7d20\u3001\u30d5\u30bf\u30ed\u30bf\u30f3\u30cb\u30f3\u3001\u30d3\u30bf\u30df\u30f3\u3001\u30df\u30cd\u30e9\u30eb\u306a\u3069\u304c\u62bd\u51fa\u3067\u304d\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6210\u5206\u306f\u3001\u975e\u5e38\u306b\u591a\u5c90\u306b\u308f\u305f\u308b\u85ac\u7406\u52b9\u679c\u3092\u6301\u3061\u3001\u6297\u816b\u760d\u6d3b\u6027\u3001\u9178\u5316\u9632\u6b62\u3001\u6297\u7d30\u83cc\u30fb\u30a6\u30a4\u30eb\u30b9\u6d3b\u6027\u3001\u6297\u51dd\u56fa\u6d3b\u6027\u3001\u514d\u75ab\u6d3b\u6027\u52b9\u679c\u306a\u3069\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u6b21\u306e\u591a\u7cd6\u985e\u306b\u3064\u3044\u3066\u3001SARS-CoV-2\u306e\u611f\u67d3\u963b\u5bb3\u52b9\u679c\u3068\u7d30\u80de\u6bd2\u6027\u304c\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\uff1a<br \/>\n\u30ef\u30ab\u30e1\u3001<br \/>\n\u30df\u30a6\u30de\u30b3\u30f3\u30d6\u3001<br \/>\n\u30d2\u30b8\u30ad\u3001<br \/>\n\u30a2\u30ab\u30e2\u30af\u3001<br \/>\n\u30a2\u30ef\u30d3\u5185\u8535\u3001<br \/>\n\u30df\u30eb\u3001<br \/>\n\u30a2\u30b5\u30af\u30b5\u30ce\u30ea\u3001\u305d\u3057\u3066<br \/>\n\u30d5\u30b3\u30a4\u30c0\u30f3\u3002<\/p>\n<p>\u7d30\u80de\u6bd2\u6027\u306f\u3001HEK293\/ACE2 \u7d30\u80de\u3092\u7528\u3044\u3066\u8a55\u4fa1\u3055\u308c\u3001\u5404\u3005\u306e\u591a\u7cd6\u985e\u306f\u30011 ng\/mL \uff5e 1 mg\/mL (1\/10\u5e0c\u91c8\u7cfb\u5217) \u306e\u6fc3\u5ea6\u306b\u3066\u30a2\u30d7\u30e9\u30a4\u3055\u308c\u300196\u6642\u9593\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30c8\u3055\u308c\u307e\u3057\u305f\u3002\u307b\u3068\u3093\u3069\u306e\u591a\u7cd6\u985e\u306f\u3001\u30b7\u30d3\u30a2\u306a\u7d30\u80de\u6bd2\u6027\u306f\u793a\u3057\u307e\u305b\u3093\u304c\u3001\u30a2\u30ef\u30d3\u5185\u8535\u3001\u30d2\u30b8\u30ad\u3001\u30a2\u30b5\u30af\u30b5\u30ce\u30ea\u306f\u30011 mg\/mL\u306e\u6fc3\u5ea6\u3067\u5c11\u3005\u7d30\u80de\u6bd2\u6027\u3092\u793a\u3057\u3001\u30a2\u30ef\u30d3\u5185\u8535 \u306e\u7d30\u80de\u6bd2\u6027\u304c\u4e00\u756a\u9855\u8457\u3067\u3042\u308a\u307e\u3057\u305f\u3002\u7d30\u80de\u6bd2\u6027\u306e\u5f37\u3055\u306e\u5ea6\u5408\u3044\u306f\u3001\u30a2\u30ef\u30d3\u5185\u8535\u3001\u30a2\u30b5\u30af\u30b5\u30ce\u30ea\u3001\u30df\u30eb\u3001\u30d2\u30b8\u30ad\u3001\u30df\u30a6\u30de\u30b3\u30f3\u30d6\u3001\u30ef\u30ab\u30e1\u3001\u30a2\u30ab\u30e2\u30af\u3001\u30d5\u30b3\u30a4\u30c0\u30f3\u306e\u9806\u306b\u4e26\u3073\u307e\u3059\u304c\u3001\u3053\u308c\u3089\u3059\u3079\u3066\u306eCC<sub>50<\/sub> \u306f\u3001500 \u03bcg\/mL\u4ee5\u4e0a\u3067\u3042\u308a\u307e\u3057\u305f\u3002 <\/p>\n<p>\u591a\u7cd6\u985e\u306b\u3088\u308b\u611f\u67d3\u963b\u5bb3\u52b9\u679c\u306f\u3001HEK293\/ACE2\u7d30\u80de\u306bSARS-CoV-2 \u7591\u4f3c\u30a6\u30a4\u30eb\u30b9\u3092\u7528\u3044\u3066\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002\u30a2\u30b5\u30af\u30b5\u30ce\u30ea\u3092\u9664\u304f\u3059\u3079\u3066\u306e\u591a\u7cd6\u985e\u304cSARS-CoV-2 \u7591\u4f3c\u30a6\u30a4\u30eb\u30b9\u306b\u5bfe\u3057\u3066\u611f\u67d3\u963b\u5bb3\u52b9\u679c\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u8a55\u4fa1\u3055\u308c\u305f\u591a\u7cd6\u985e\u306e\u4e2d\u3067\u306f\u3001\u30a2\u30ab\u30e2\u30af\u304c\u6700\u3082\u9ad8\u3044\u6297\u30a6\u30a4\u30eb\u30b9\u52b9\u679c\u3092\u793a\u3057\u3001IC<sub>50<\/sub> \u306f 12 \u03bcg\/mL\u3067\u3042\u308a\u307e\u3057\u305f\u3002\u305d\u306e\u4ed6\u306f\u3001\u6b21\u306e\u3088\u3046\u306a\u9806\u756a\u306b\u306a\u308a\u307e\u3059\u3001\u30a2\u30ef\u30d3\u5185\u8535 (33 \u03bcg\/mL)\u3001\u30d2\u30b8\u30ad (47 \u03bcg\/mL)\u3001\u30df\u30eb (74 \u03bcg\/mL)\u3001\u30df\u30a6\u30de\u30b3\u30f3\u30f3\u30d6 (105 \u03bcg\/mL)\u3001 \u30d5\u30b3\u30a4\u30c0\u30f3 (142 \u03bcg\/mL)\u3001\u30ef\u30ab\u30e1 (289 \u03bcg\/mL)\u3001\u3067\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u7d50\u8ad6\u3068\u3057\u3066\u306f\u3001\u30a2\u30ab\u30e2\u30af\u306e\u591a\u7cd6\u985e\u304cSARS-CoV-2\u306e\u611f\u67d3\u963b\u5bb3\u306b\u306f\u6700\u3082\u9069\u3057\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Marine Biotechnology Research Center, Korea\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6d77\u85fb\u304b\u3089\u62bd\u51fa\u3057\u305f\u591a\u7cd6\u985e\u306eSARS-CoV-2\u306e\u611f\u67d3\u963b\u5bb3\u52b9\u679c\u3068\u7d30\u80de\u6bd2\u6027\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/www.<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e6%b5%b7%e8%97%bb%e3%81%8b%e3%82%89%e6%8a%bd%e5%87%ba%e3%81%95%e3%82%8c%e3%82%8b%e5%a4%9a%e7%b3%96%e9%a1%9e%e3%81%aesars-cov-2%e3%81%ae%e6%84%9f%e6%9f%93%e9%98%bb%e5%ae%b3%e5%8a%b9%e6%9e%9c%e3%81%ab\/\" 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