{"id":4843,"date":"2021-07-14T15:02:30","date_gmt":"2021-07-14T06:02:30","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=4840"},"modified":"2021-07-14T15:06:47","modified_gmt":"2021-07-14T06:06:47","slug":"protection-from-kappa-variant-b-1-617-1-and-delta-variant-b-1-617-2-by-pfizer-biontech-or-oxford-astrazeneca-vaccine-serum","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/protection-from-kappa-variant-b-1-617-1-and-delta-variant-b-1-617-2-by-pfizer-biontech-or-oxford-astrazeneca-vaccine-serum\/","title":{"rendered":"Protection from kappa variant (B.1.617.1) and delta variant (B.1.617.2) by Pfizer-BioNTech or Oxford-AstraZeneca vaccine serum \u00a0"},"content":{"rendered":"<p>A group from University of Oxford, Oxford, UK, etc. has reported on protection from B.1.617.1 and B.1.617.2 by vaccine serum.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8218332\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8218332\/<\/a><\/p>\n<p>Kappa variant = B.1.617.1 is characterized by two mutations L452R and E484Q in the RBD, and delta variant = B.1.617.2 is characterized by two mutations L452R and T478K in the RBD). The L452R mutation is the common in those variants.<\/p>\n<p>Authors tested neutralization of B.1.617.1 and B.1.617.2 using serum from individuals who had received 2 doses of the BNT162b2 Pfizer-BioNTech or ChAdOx1 nCoV-19 Oxford-AstraZeneca vaccine. <\/p>\n<p>Geometric mean neutralization titers against <strong>B.1.617.1<\/strong> were reduced 2.7-fold (p < 0.0001) relative to the Victoria virus for the Pfizer-BioNTech vaccine serum, and 2.6-fold (p < 0.0001) for the Oxford-AstraZeneca vaccine. The Victoria virus is a Wuhan-related strain isolated early in the pandemic from Australia.\n\nFor <strong>B.1.617.2<\/strong>, titers were reduced 2.5-fold (p < 0.0001) relative to the Victoria virus for the Pfizer-BioNTech vaccine serum and 4.3-fold (p < 0.0001) for the Oxford-AstraZeneca vaccine. \n\nAlthough significant reductions in neutralization titers of sera collected from recipients of the Oxford-AstraZeneca and Pfizer-BioNTech vaccines were observed as such, but make sure that there is no evidence of complete escape from neutralization.\n\u00a0\n\n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from University of Oxford, Oxford, UK, etc. has reported on protection from B.1.617.1 and B.1.617.2 by<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/protection-from-kappa-variant-b-1-617-1-and-delta-variant-b-1-617-2-by-pfizer-biontech-or-oxford-astrazeneca-vaccine-serum\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70,7],"tags":[],"class_list":["post-4843","post","type-post","status-publish","format-standard","hentry","category-nature-en","category-technology-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/4843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=4843"}],"version-history":[{"count":2,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/4843\/revisions"}],"predecessor-version":[{"id":4845,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/4843\/revisions\/4845"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=4843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=4843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=4843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}