{"id":4765,"date":"2021-07-11T08:53:40","date_gmt":"2021-07-10T23:53:40","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=4765"},"modified":"2021-07-21T22:53:05","modified_gmt":"2021-07-21T13:53:05","slug":"covid-19%e5%9b%9e%e5%be%a9%e6%9c%9f%e6%82%a3%e8%80%85%e3%81%8b%e3%82%89%e5%be%97%e3%81%9f%e6%8a%97%e4%bd%93%e3%81%aesars-cov-2%e5%a4%89%e7%95%b0%e6%a0%aa%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e6%8a%b5","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/covid-19%e5%9b%9e%e5%be%a9%e6%9c%9f%e6%82%a3%e8%80%85%e3%81%8b%e3%82%89%e5%be%97%e3%81%9f%e6%8a%97%e4%bd%93%e3%81%aesars-cov-2%e5%a4%89%e7%95%b0%e6%a0%aa%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e6%8a%b5\/","title":{"rendered":"COVID-19\u56de\u5fa9\u671f\u60a3\u8005\u304b\u3089\u5f97\u305f\u6297\u4f53\u306eSARS-CoV-2\u5909\u7570\u682a\u306b\u5bfe\u3059\u308b\u62b5\u6297\u6027\u306e\u8a55\u4fa1"},"content":{"rendered":"

\u718a\u672c\u5927\u5b66\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u56de\u5fa9\u671f\u60a3\u8005\u7531\u6765\u3067SARS-CoV-2 RBD\u306b\u5f37\u3044\u30a2\u30d5\u30a3\u30cb\u30c6\u30a3\u30fc\u3092\u6301\u3064IgG\u306f\u3001B.1.351\u3084P.1\u5909\u7570\u682a\u306b\u5bfe\u3057\u3066\u3082\u52b9\u679c\u7684\u306a\u4e2d\u548c\u6d3b\u6027\u3092\u6709\u3059\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/pubmed.ncbi.nlm.nih.gov\/34237284\/<\/a><\/p>\n

1102\u7a2e\u985e\u306eIgG\u3092\u30012020\u5e743\u6708\u306bSARS-CoV-2\u306b\u611f\u67d3\u3057\u305fCOVID-19\u56de\u5fa9\u671f\u60a3\u8005=2\u540d\u304b\u3089Recombinant IgG\u3068\u3057\u3066\u5f97\u308b\u3053\u3068\u304c\u51fa\u6765\u307e\u3057\u305f\u3002\u3053\u306e\u518588\u7a2e\u304cSARS-CoV-2 Spike\u306b\u7d50\u5408\u3057\u3001\u305d\u306e\u5185\u306e10%\u304cRBD\u306b\u7d50\u5408\u3057\u307e\u3057\u305f\u3002\u6700\u7d42\u7684\u306b\u4e2d\u548c\u6d3b\u6027\u304c\u78ba\u8a8d\u3055\u308c\u305fIgG\u306f\u30015\u7a2e\u985e\u3068\u306a\u308a\u307e\u3057\u305f\u3002
\n\"\"<\/a><\/p>\n

\u5f97\u3089\u308c\u305f5\u7a2e\u985e\u306eIgG\u3067\u3059\u304c\u3001\u3072\u3068\u3064\u306fNTD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u3066\u304a\u308a\uff08= 6-74\uff09\u3001\u56db\u3064\u306eIgG\u306f\u3001RBD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u3066\u3044\u307e\u3057\u305f\uff08= 3-5\u30018-92\u30019-105\u300110-121\uff09\u3002<\/p>\n

\u3053\u308c\u3089mAb\u306e\u4e2d\u548c\u6d3b\u6027\u3092\u3001WT\uff08614G\u5909\u7570\u3092\u542b\u3080\uff09\u304a\u3088\u3073B.1.1.7\u3001B.1.351\u3001P.1\u3001and mink cluster 5\u3068\u3044\u3046\u5909\u7570\u682a\u306b\u5bfe\u3057\u3066\u6e2c\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002\u307b\u3068\u3093\u3069\u306emAb\u306f\u3001B.1.1.7\u3001mink cluster 5\u5909\u7570\u682a\u306b\u5bfe\u3057\u3066\u540c\u7a0b\u5ea6\u306e\u5f37\u3055\u3067\u4e2d\u548c\u6d3b\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002B.1.1.7\u306f\u30016-74 (3.3-\u500d) \u3068 3-5 (6.0-\u500d)\u306b\u5bfe\u3057\u3066\u306f\u62b5\u6297\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002NTD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3059\u308b 6-74\u306f\u3001mink cluster 5\u306b\u5bfe\u3057\u3066\u306f\u52b9\u679c\u7684\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u4e2d\u548c\u6d3b\u6027\u306f\u3001B.1.351\u3084P.1\u306b\u5bfe\u3057\u3066\u306f\u4f4e\u4e0b\u3057\u3066\u304a\u308a\u3001P.1 \u306f\u30016-74 \u3084 3-5 \u3067\u306f\u4e2d\u548c\u6d3b\u6027\u304c\u9855\u8457\u306b\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u4ed6\u306emAb\u306b\u6bd4\u3079\u3066\u30012.6- \u304b\u3089 8.0-\u500d\uff09\u3002 B.1.351 \u306f\u30019-105 \u3084 10-121\u3067\u4e2d\u548c\u3055\u308c\u307e\u3057\u305f\u304c\u30016-74\u30013-5\u30018-92\u3067\u306f\u4e2d\u548c\u3055\u308c\u307e\u305b\u3093\u30029-105 \u3068 10-121 \u306f\u3001B.1.351 \u306b\u5bfe\u3057\u3066\u306f\u4e2d\u548c\u6d3b\u6027\u304c\u4f4e\u4e0b\u3057\u307e\u3057\u305f\uff08\u305d\u308c\u305e\u308c\u30016.0-\u500d \u300119-\u500d\uff09\u3002<\/p>\n

\u8a55\u4fa1\u3057\u305f\u5909\u7570\u682a\u306f\u30016-74\u306b\u5bfe\u3057\u3066\u306f\u62b5\u6297\u6027\u3092\u793a\u3057\u3001\u3053\u308c\u306f\u6050\u3089\u304f\u3001NTD\u306b\u767a\u751f\u3057\u3066\u3044\u308b\u5909\u7570\u306e\u5f71\u97ff\u3060\u3068\u601d\u308f\u308c\u307e\u3059\u3002RBD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3059\u308bmAb\u306e\u4e2d\u548c\u6d3b\u6027\u306f\u3001P.1 \u3068 B.1.351\u306b\u5bfe\u3057\u3066\u6e1b\u5c11\u3057\u3066\u304a\u308a\u3001K417N\/T\u3001E484K\u3001N501Y \u5909\u7570\u304c\u30af\u30ea\u30c6\u30a3\u30ab\u30eb\u306a\u306e\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u500b\u3005\u306e\u5909\u7570\u304c\u53ca\u307c\u3059\u5f71\u97ff\u3092\u89e3\u6790\u3059\u308b\u3068\u3001K417N \u3068 K417T \u306f\u30013-5\u306b\u5bfe\u3057\u3066\u306f\u30af\u30ea\u30c6\u30a3\u30ab\u30eb\u3067\u3042\u308a\u30018-92\u306b\u5bfe\u3057\u3066\u5c11\u3057\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u307e\u3059\u3002E484K \u3068 N501Y\u306f\u3001RBD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3059\u308bmAb\u306b\u5bfe\u3057\u3066\u306f\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u307e\u305b\u3093\u3002 \u3057\u304b\u3057\u306a\u304c\u3089\u3001K417N\u3001E484K\u3001N501Y\u306e\u30b3\u30f3\u30d3\u30cd\u30fc\u30b7\u30e7\u30f3\u3067\u306f\u30013-5\u30018-92\u300110-121\u306e\u4e2d\u548c\u6d3b\u6027\u304c\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u8208\u5473\u6df1\u3044\u306e\u306f\u30019-105 \u306f\u3001K417N \u306e\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u304c\u3001\u3053\u308c\u30893\u500b\u306e\u5909\u7570\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u5bfe\u3057\u3066\u306f\u3001\u52b9\u679c\u7684\u306a\u4e2d\u548c\u6d3b\u6027\u3092\u3057\u307e\u3057\u307e\u3057\u305f\u3002\u4eca\u5f8c\u3068\u3082\u767a\u751f\u3059\u308b\u5909\u7570\u306b\u5bfe\u3059\u308b\u5f71\u97ff\u3092\u8abf\u67fb\u3057\u3066\u3044\u304f\u3053\u3068\u306f\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u718a\u672c\u5927\u5b66\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u56de\u5fa9\u671f\u60a3\u8005\u7531\u6765\u3067SARS-CoV-2 RBD\u306b\u5f37\u3044\u30a2\u30d5\u30a3\u30cb\u30c6\u30a3\u30fc\u3092\u6301\u3064IgG\u306f\u3001B.1.351\u3084P.1\u5909\u7570\u682a\u306b\u5bfe\u3057\u3066\u3082\u52b9\u679c\u7684\u306a\u4e2d\u548c\u6d3b\u6027\u3092\u6709\u3059\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002 https:\/\/pu<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-4765","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/4765","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=4765"}],"version-history":[{"count":11,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/4765\/revisions"}],"predecessor-version":[{"id":5048,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/4765\/revisions\/5048"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=4765"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=4765"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=4765"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}