{"id":4615,"date":"2021-07-07T13:41:10","date_gmt":"2021-07-07T04:41:10","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=4615"},"modified":"2021-07-21T22:54:55","modified_gmt":"2021-07-21T13:54:55","slug":"sars-cov-2%e6%84%9f%e6%9f%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8bcd147%e3%81%ae%e5%bd%b9%e5%89%b2%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/sars-cov-2%e6%84%9f%e6%9f%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8bcd147%e3%81%ae%e5%bd%b9%e5%89%b2%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6\/","title":{"rendered":"SARS-CoV-2\u611f\u67d3\u306b\u304a\u3051\u308bCD147\u306e\u5f79\u5272\u306b\u3064\u3044\u3066"},"content":{"rendered":"<p>Milano University Medical School, Milano, Italy\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001SARS-CoV-2\u306e\u611f\u67d3\u306b\u304a\u3051\u308bCD147\u306e\u5f79\u5272\u306b\u3064\u3044\u3066\u30ec\u30dd\u30fc\u30c8\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.mdpi.com\/2073-4409\/10\/6\/1434\">https:\/\/www.mdpi.com\/2073-4409\/10\/6\/1434<\/a><\/p>\n<p>CD147 \u306f\u3001\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u306e\u30b9\u30fc\u30d1\u30fc\u30d5\u30a1\u30df\u30ea\u30fc\u306b\u5c5e\u3057\u3001\u8272\u3005\u306a\u7d44\u7e54\u306b\u767a\u73fe\u3057\u3066\u3044\u307e\u3059\u3002CD147\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u306f\u3001HIV-1\u3001HCV\u3001HBV\u3001KSHV\u3089\u306e\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306e\u7814\u7a76\u306b\u304a\u3044\u3066\u793a\u3055\u308c\u3066\u304a\u308a\u3001CD147\u3068cyclophilin A (CyPA) \u3068\u306e\u76f8\u4e92\u4f5c\u7528\u304c\u3053\u308c\u3089\u306e\u30a6\u30a4\u30eb\u30b9\u306e\u611f\u67d3\u80fd\u529b\u3092\u5de6\u53f3\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u305d\u306e\u80cc\u666f\u306b\u3042\u308a\u307e\u3059\u3002\u6628\u5e74\u672b\u306b\u306f\u3001\u3053\u306eCD147\u304cSARS-CoV-2\u306e\u611f\u67d3\u306b\u304a\u3044\u3066\u3082\u53d7\u5bb9\u4f53\u3068\u3057\u3066\u4fc2\u308f\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u6307\u6458\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u306e\u3088\u3046\u306a\u80cc\u666f\u306e\u5143\u3001\u8457\u8005\u3089\u306f\u3001CD147\u304cSARS-CoV-2\u306e\u611f\u67d3\u306b\u304a\u3044\u3066\u5982\u4f55\u306a\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u306e\u304b\u306b\u3064\u3044\u3066\u7814\u7a76\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\nCD147\u306b\u5bfe\u3059\u308b\u6297\u4f53\u3067\u963b\u5bb3\u3057\u305f\u7d50\u679c\u306f\uff08\u03b1-CD147 Ab\uff09\u3001SARS-CoV-2\u306e\u611f\u67d3\u80fd\u529b\u306b\u306f\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u304a\u3089\u305a\u3001SARS-CoV-2\u306e\u611f\u67d3\u306b\u304a\u3044\u3066\u306f\u3001CyPA\u3068CD147\u306e\u76f8\u4e92\u4f5c\u7528\u306f\u91cd\u8981\u3067\u306a\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/blocking-CD147_SARS-CoV-2-infection.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/blocking-CD147_SARS-CoV-2-infection-300x300.png\" alt=\"\" width=\"300\" height=\"300\" class=\"alignleft size-medium wp-image-4622\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/blocking-CD147_SARS-CoV-2-infection-300x300.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/blocking-CD147_SARS-CoV-2-infection-100x100.png 100w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/blocking-CD147_SARS-CoV-2-infection-150x150.png 150w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/blocking-CD147_SARS-CoV-2-infection.png 442w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>CD147 siRNA \u5e72\u6e09\u3067CD147\u3092\u30b5\u30a4\u30ec\u30f3\u30b7\u30f3\u30b0\u3055\u305b\u305f\u7d50\u679c\u306f\u3001ACE2\u306e\u767a\u73fe\u91cf\u306e\u4f4e\u4e0b\u3068\u7d61\u3093\u3067\u80ba\u7d30\u80de\u3078\u306eSARS-CoV-2\u306e\u611f\u67d3\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u304a\u308a\u3001CD147\u304cACE2\u306e\u7ffb\u8a33\u5f8c\u4fee\u98fe\u306e\u30ec\u30d9\u30eb\u3067ACE2\u306e\u767a\u73fe\u5236\u5fa1\u306b\u95a2\u308f\u308b\u80fd\u529b\u3092\u6301\u3063\u3066\u3001\u76f4\u63a5\u7684\u6216\u3044\u306f\u9593\u63a5\u7684\u306bCD147\u304cSARS-CoV-2\u306e\u611f\u67d3\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/CD147-silensing_SARS-CoV-2-infection.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/CD147-silensing_SARS-CoV-2-infection-159x300.png\" alt=\"\" width=\"159\" height=\"300\" class=\"alignleft size-medium wp-image-4623\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/CD147-silensing_SARS-CoV-2-infection-159x300.png 159w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/CD147-silensing_SARS-CoV-2-infection.png 331w\" sizes=\"auto, (max-width: 159px) 100vw, 159px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Milano University Medical School, Milano, Italy\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001SARS-CoV-2\u306e\u611f\u67d3\u306b\u304a\u3051\u308bCD147\u306e\u5f79\u5272\u306b\u3064\u3044\u3066\u30ec\u30dd\u30fc\u30c8\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/www.mdp<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/sars-cov-2%e6%84%9f%e6%9f%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8bcd147%e3%81%ae%e5%bd%b9%e5%89%b2%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-4615","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Milano University Medical School, Milano, Italy\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" 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