{"id":4560,"date":"2021-07-06T14:37:35","date_gmt":"2021-07-06T05:37:35","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=4560"},"modified":"2021-07-21T22:55:19","modified_gmt":"2021-07-21T13:55:19","slug":"covid-19%e8%bb%bd%e7%97%87%e5%9b%9e%e5%be%a9%e6%9c%9f%e6%82%a3%e8%80%85%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e6%8a%97%e4%bd%93%e3%81%ae%e3%82%a8%e3%83%95%e3%82%a7%e3%82%af%e3%82%bf%e3%83%bc%e5%8a%b9","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/covid-19%e8%bb%bd%e7%97%87%e5%9b%9e%e5%be%a9%e6%9c%9f%e6%82%a3%e8%80%85%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e6%8a%97%e4%bd%93%e3%81%ae%e3%82%a8%e3%83%95%e3%82%a7%e3%82%af%e3%82%bf%e3%83%bc%e5%8a%b9\/","title":{"rendered":"COVID-19\u8efd\u75c7\u56de\u5fa9\u671f\u60a3\u8005\u306b\u304a\u3051\u308b\u6297\u4f53\u306e\u30a8\u30d5\u30a7\u30af\u30bf\u30fc\u52b9\u679c\uff08ADCC, ADP\uff09\u306e\u7d4c\u6642\u5909\u5316\u306b\u3064\u3044\u3066"},"content":{"rendered":"<p>University of Melbourne, Australia\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u8efd\u75c7\u56de\u5fa9\u671f\u60a3\u8005\u306b\u304a\u3051\u308bFc-\u4f9d\u5b58\u306e\u30a8\u30d5\u30a7\u30af\u30bf\u30fc\u52b9\u679c\u306e\u7d4c\u6642\u5909\u5316\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8106889\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8106889\/<\/a><\/p>\n<p>SARS-CoV-2 Spike\u7279\u7570\u7684\u306a\u6297\u4f53\u304cFc\u03b3\u53d7\u5bb9\u4f53\u3068\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u8a98\u8d77\u3055\u308c\u308b antibody-dependent cellular cytotoxicity (ADCC) \u3084 antibody-dependent phagocytosis (ADP) \u6d3b\u6027\u306f\u3001\u6642\u9593\u7d4c\u904e\u3068\u3068\u3082\u306b\u6e1b\u8870\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u672c\u30b3\u30db\u30fc\u30c8\u3067\u306f\u3001\u6700\u521d\u306e\u30b5\u30f3\u30d7\u30eb\u306fSARS-CoV-2\u611f\u67d3\u5f8c\u306e\u4e2d\u592e\u5024\u3068\u3057\u306641\u65e5\u76ee\u306b\u63a1\u53d6\u3055\u308c\u3001\u6700\u5f8c\u306e\u30b5\u30f3\u30d7\u30eb\u306f\u611f\u67d3\u5f8c\u306e\u4e2d\u592e\u5024123\u65e5\u76ee\u306b\u63a1\u53d6\u3055\u308c\u3066\u3044\u307e\u3059\u3002ADCC\u3084ADP\u6d3b\u6027\u306e\u7d4c\u6642\u5909\u5316\u306f\u3001SARS-CoV-2 Spike\u7279\u7570\u7684\u306aIgG\u3068Fc\u03b3\u53d7\u5bb9\u4f53\u7d50\u5408\u6297\u4f53\u306e\u305d\u308c\u3068\u76f8\u95a2\u3057\u3066\u3044\u307e\u3059\uff08\u4e0b\u56f3\u53c2\u7167\uff09\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/Decay-of-Fc-dependent-functions.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/Decay-of-Fc-dependent-functions-300x176.png\" alt=\"\" width=\"300\" height=\"176\" class=\"alignleft size-medium wp-image-4563\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/Decay-of-Fc-dependent-functions-300x176.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/Decay-of-Fc-dependent-functions-600x352.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/07\/Decay-of-Fc-dependent-functions.png 668w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u91cd\u8981\u306a\u3053\u3068\u306f\u3001Fc-\u4f9d\u5b58\u306e\u30a8\u30d5\u30a7\u30af\u30bf\u30fc\u52b9\u679c\u306f\u3001\u6700\u5f8c\u306e\u30b5\u30f3\u30d7\u30ea\u30f3\u30b0\u6642\u70b9\u3067\u307b\u3068\u3093\u3069\u3059\u3079\u3066\u306e\u88ab\u9a13\u8005\u3067\u5bb9\u6613\u306b\u691c\u51fa\u53ef\u80fd\uff0894%\uff09\u3067\u3042\u308b\u306e\u306b\u5bfe\u3057\u3001\u691c\u51fa\u53ef\u80fd\u306a\u4e2d\u548c\u6d3b\u6027\u306f\u540c\u3058\u6642\u70b9\u306770\uff05\u306b\u7559\u307e\u3063\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u5168\u822c\u7684\u306b\u8a00\u3048\u308b\u306e\u306f\u3001\u8efd\u75c7\u306eCOVID-19\u306b\u304a\u3044\u3066\u306f\u3001\u5f37\u3044Fc\u03b3\u53d7\u5bb9\u4f53\u7d50\u5408\u3001ADCC\u3001ADP\u6d3b\u6027\u3089\u304c\u5f15\u304d\u51fa\u3055\u308c\u3066\u304a\u308a\u3001\u305d\u308c\u3089\u306f\u4e2d\u548c\u6d3b\u6027\u306e\u6e1b\u8870\u3088\u308a\u3082\u7de9\u3084\u304b\u306b\u6e1b\u5c11\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3057\u3087\u3046\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of Melbourne, Australia\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u8efd\u75c7\u56de\u5fa9\u671f\u60a3\u8005\u306b\u304a\u3051\u308bFc-\u4f9d\u5b58\u306e\u30a8\u30d5\u30a7\u30af\u30bf\u30fc\u52b9\u679c\u306e\u7d4c\u6642\u5909\u5316\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/www.ncbi.<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/covid-19%e8%bb%bd%e7%97%87%e5%9b%9e%e5%be%a9%e6%9c%9f%e6%82%a3%e8%80%85%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e6%8a%97%e4%bd%93%e3%81%ae%e3%82%a8%e3%83%95%e3%82%a7%e3%82%af%e3%82%bf%e3%83%bc%e5%8a%b9\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-4560","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"University of Melbourne, Australia\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u8efd\u75c7\u56de\u5fa9\u671f\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" 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