{"id":4243,"date":"2021-06-19T07:02:18","date_gmt":"2021-06-18T22:02:18","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=4237"},"modified":"2021-06-19T07:05:02","modified_gmt":"2021-06-18T22:05:02","slug":"whether-abo-blood-group-or-secretor-status-was-associated-with-covid-19-severity","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/whether-abo-blood-group-or-secretor-status-was-associated-with-covid-19-severity\/","title":{"rendered":"Whether ABO blood group or secretor status was associated with COVID-19 severity\u00a0"},"content":{"rendered":"

A group from Bristol Institute for Transfusion Sciences (BITS), NHSBT, UK, etc. has investigated whether ABO blood group or secretor status was associated with COVID-19 severity.
\nhttps:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jha2.180<\/a><\/p>\n

A number of studies carried out in several countries have supported an association between ABO type and SARS-CoV-2 susceptibility to infection and\/or outcomes. The reasons for the association of severe COVID-19 with blood type A are unknown, but it has been suggested that this could be caused by O group patients having anti-A type antibodies, that A type glycans could function as co-receptors for SARS-CoV-2 or due to the known effects of blood groups on thrombosis risk due to von Willebrand factor (VWF) levels.<\/p>\n

The result obtained here is that the association of blood group A with hospitalization was (RR = 1.24, CI 95% [1.05, 1.47], p = 0.0111), and blood group A with cardiovascular complications was greatly increased (RR = 2.56, CI 95% [1.43, 4.55], p = 0.0011), but group A non-secretors were significantly less likely to be hospitalized than secretors. Why the difference between group A and O was so large in COVID-19 related cardiovascular complications was considered to be due to VWF related origins.<\/p>\n

As is known, in the presence of active FUT2 A, B, H, and Lewis b antigens can be expressed on mucosal surfaces. Individuals with this phenotype are known as secretors. In individuals lacking active FUT2, known as non-secretors, only the Lewis a antigen can be expressed.\u00a0 \u00a0 \u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"

A group from Bristol Institute for Transfusion Sciences (BITS), NHSBT, UK, etc. has investigated whether ABO b<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-4243","post","type-post","status-publish","format-standard","hentry","category-nature-en"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t