{"id":3976,"date":"2021-06-01T06:43:19","date_gmt":"2021-05-31T21:43:19","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3976"},"modified":"2021-07-21T23:08:11","modified_gmt":"2021-07-21T14:08:11","slug":"rna%e3%81%8c%e7%b3%96%e9%8e%96%e4%bf%ae%e9%a3%be%e3%82%92%e5%8f%97%e3%81%91%e3%81%a6%e3%81%84%e3%82%8b%e3%81%a8%e3%81%84%e3%81%86%e4%bf%a1%e3%81%98%e3%81%8c%e3%81%9f%e3%81%84%e7%99%ba%e8%a6%8b","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/rna%e3%81%8c%e7%b3%96%e9%8e%96%e4%bf%ae%e9%a3%be%e3%82%92%e5%8f%97%e3%81%91%e3%81%a6%e3%81%84%e3%82%8b%e3%81%a8%e3%81%84%e3%81%86%e4%bf%a1%e3%81%98%e3%81%8c%e3%81%9f%e3%81%84%e7%99%ba%e8%a6%8b\/","title":{"rendered":"RNA\u304c\u7cd6\u9396\u4fee\u98fe\u3092\u53d7\u3051\u3066\u3044\u308b\u3068\u3044\u3046\u4fe1\u3058\u304c\u305f\u3044\u767a\u898b"},"content":{"rendered":"<p>Stanford Univ.\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001small noncoding RNA\u304c\u7cd6\u9396\u4fee\u98fe\u306e\u4e09\u756a\u76ee\u306e\u8db3\u5834\u306b\u306a\u308b\u3068\u3044\u3046\u9a5a\u304f\u3079\u304d\u767a\u898b\u3092\u3057\u307e\u3057\u305f\u3002<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34004145\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34004145\/<\/a><\/p>\n<p>\u7cd6\u9396\u4fee\u98fe\u3092\u53d7\u3051\u305fRNA\uff08GlycoRNA\u3068\u547d\u540d\uff09\u306e\u5b58\u5728\u306f\u3001\u6b21\u306e\u3088\u3046\u306a\u30d7\u30ed\u30c8\u30b3\u30eb\u3092\u7528\u3044\u3066\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002\u8457\u8005\u3089\u306f\u3001\u7d30\u80de\u3092peracetylated N-azidoacetylmannosamine (Ac4ManNAz)\u3092\u7528\u3044\u3066\u4ee3\u8b1d\u7684\u306b\u30e9\u30d9\u30ea\u30f3\u30b0\u3057\u305f\u5f8c\u3001RNA\u3092TRIzol\u3067\u62bd\u51fa\u3057\u3001\u30a8\u30bf\u30ce\u30fc\u30eb\u3067\u6c88\u6bbf\u3055\u305b\u3001\u30b7\u30ea\u30ab\u30ab\u30e9\u30e0\u3067\u8131\u5869\u5316\u3057\u3001\u9ad8\u6fc3\u5ea6\u306eproteinase K digestion\u306b\u3088\u3063\u3066\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u9664\u53bb\u3057\u3001\u30b7\u30ea\u30ab\u30ab\u30e9\u30e0\u3067\u518d\u7cbe\u88fd\u3057\u307e\u3057\u305f\u3002RNA\u3092\u7cbe\u88fd\u3057\u305f\u5f8c\u3001DBCO-biotin\u3092\u52a0\u3048\u3066\u7d50\u5408\u3055\u305b\u3001streptavidin-IR800\u3092\u7528\u3044\u3066\u53ef\u8996\u5316\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u7cd6\u9396\u4fee\u98fe\u3092\u53d7\u3051\u308bRNA\u306e\u8db3\u5834\u306f\u3001micro noncoding RNA\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002GlycoRNA\u306e\u5927\u90e8\u5206\u306f\u7d30\u80de\u819c\u8868\u9762\u306b\u5b58\u5728\u3057\u3001\u5c11\u306a\u304f\u3068\u3082\u4e00\u3064\u306e\u30b7\u30a2\u30eb\u9178\u4fee\u98fe\u3092\u53d7\u3051\u305f\u8907\u5408\u578bN\u578b\u7cd6\u9396\u3067\u4fee\u98fe\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u307e\u305f\u3001GlycoRNA\u306fSiglec\u3068\u76f4\u63a5\u7684\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycoRNA_Siglec.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycoRNA_Siglec-233x300.png\" alt=\"\" width=\"233\" height=\"300\" class=\"alignleft size-medium wp-image-3981\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycoRNA_Siglec-233x300.png 233w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycoRNA_Siglec.png 279w\" sizes=\"auto, (max-width: 233px) 100vw, 233px\" \/><\/a><\/p>\n<p>\u73fe\u5728\u306e\u751f\u7269\u5b66\u3067\u306f\u3001N\u578b\u7cd6\u9396\u4fee\u98fe\u306e\u8db3\u5834\u3068\u3057\u3066\u306f\u3001RNA\u306f\u9664\u5916\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306eGlycoRNA\u306e\u767a\u898b\u306f\u3001\u73fe\u5728\u306e\u751f\u7269\u5b66\u306b\u554f\u984c\u304c\u3042\u308a\u3001RNA\u7cd6\u9396\u30ef\u30fc\u30eb\u30c9\u3068\u3044\u3046\u65b0\u3057\u3044\u8996\u70b9\u3092\u52a0\u3048\u308b\u3079\u304d\u3082\u306e\u3067\u3042\u308b\u3053\u3068\u3092\u4e3b\u5f35\u3057\u3066\u3044\u307e\u3059\u3002\u66f4\u306b\u3001\u7d30\u80de\u5185\u5916\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u4ecb\u5728\u5236\u5fa1\u3059\u308b\u7d30\u80de\u8868\u9762\u306e\u65b0\u3057\u3044\u8907\u5408\u7cd6\u8cea\u306e\u5b58\u5728\u53ef\u80fd\u6027\u3092\u8b33\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Stanford Univ.\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001small noncoding RNA\u304c\u7cd6\u9396\u4fee\u98fe\u306e\u4e09\u756a\u76ee\u306e\u8db3\u5834\u306b\u306a\u308b\u3068\u3044\u3046\u9a5a\u304f\u3079\u304d\u767a\u898b\u3092\u3057\u307e\u3057\u305f\u3002 https:\/\/pubmed.ncbi.nlm.nih.gov\/340041<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/rna%e3%81%8c%e7%b3%96%e9%8e%96%e4%bf%ae%e9%a3%be%e3%82%92%e5%8f%97%e3%81%91%e3%81%a6%e3%81%84%e3%82%8b%e3%81%a8%e3%81%84%e3%81%86%e4%bf%a1%e3%81%98%e3%81%8c%e3%81%9f%e3%81%84%e7%99%ba%e8%a6%8b\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-3976","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" 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