{"id":3894,"date":"2021-05-22T11:51:47","date_gmt":"2021-05-22T02:51:47","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3894"},"modified":"2021-07-21T23:09:12","modified_gmt":"2021-07-21T14:09:12","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars-cov-2%ef%bc%89%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e4%ba%a4%e5%b7%ae%e5%8f%8d%e5%bf%9c%e8%a1%80","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars-cov-2%ef%bc%89%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e4%ba%a4%e5%b7%ae%e5%8f%8d%e5%bf%9c%e8%a1%80\/","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306b\u304a\u3051\u308b\u4ea4\u5dee\u53cd\u5fdc\u8840\u6e05\u3068\u30e1\u30e2\u30ea\u30fcB\u7d30\u80de\u306e\u53cd\u5fdc\u6027\u306b\u3064\u3044\u3066"},"content":{"rendered":"<p>Scripps Research Institute\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u3068\u5b63\u7bc0\u6027\u306e\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08HCoVs\uff09\u306e\u9593\u306b\u5b58\u5728\u3059\u308b\u4ea4\u5dee\u53cd\u5fdc\u8840\u6e05\u3068\u30e1\u30e2\u30ea\u30fcB\u7d30\u80de\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.nature.com\/articles\/s41467-021-23074-3\">https:\/\/www.nature.com\/articles\/s41467-021-23074-3<\/a><\/p>\n<p>36\u540d\u306eCOVID-19\u56de\u5fa9\u671f\u8840\u6e05\u306f\u3001SARS-CoV-2 Spike\u306b\u5f37\u3044\u53cd\u5fdc\u6027\u3092\u793a\u3057\u3001SARS-CoV-1\u306b\u5bfe\u3057\u3066\u306f\u305d\u3053\u305d\u3053\u306e\u3001MARS-CoV\u306b\u5bfe\u3057\u3066\u306f\u5f31\u3044\u53cd\u5fdc\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001HCoVs\u3068\u3082\u5f37\u3044\u4ea4\u5dee\u53cd\u5fdc\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u7279\u306b\u03b2-\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3067\u3042\u308bHCoV-HKU1 \u3068 HCoV-OC43\u306b\u5bfe\u3057\u3066\u306f\u5f37\u3044\u4ea4\u5dee\u53cd\u5fdc\u6027\u3092\u793a\u3057\u3001\u03b1-\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3067\u3042\u308bHCoV-NL63\u306b\u5bfe\u3057\u3066\u306f\u4e00\u756a\u5f31\u3044\u4ea4\u5dee\u53cd\u5fdc\u3092\u793a\u3057\u307e\u3057\u305f\u3002 HIV\u611f\u67d3\u8005\u3067\u306f\u3042\u308a\u307e\u3059\u304c\u305d\u308c\u4ee5\u5916\u306f\u5065\u5e38\u306a36\u540d\u306eSARS-CoV-2\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u4ee5\u524d\u306b\u63a1\u53d6\u3055\u308c\u305f\u8840\u6e05\u306f\u3001SARS-CoV-2\/SARS-CoV-1 \u3084 MERS-CoV \u306b\u5bfe\u3057\u3066\u306f\u307b\u3068\u3093\u3069\u53cd\u5fdc\u6027\u3092\u793a\u3055\u305a\u3001HCoVs\u306b\u5bfe\u3057\u3066\u306f\u5f37\u3044\u53cd\u5fdc\u6027\u3092\u793a\u3057\u307e\u3057\u305f\uff08\u4e0b\u56f3\u3092\u53c2\u7167\uff09\u3002<\/p>\n<p>\u3053\u306eSARS-CoV-2\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u4ee5\u524d\u306e\u30b3\u30db\u30fc\u30c8\u306e\u30b5\u30f3\u30d7\u30eb\u3067\u306f\u3001HCoVs\u306e\u611f\u67d3\u3067\u751f\u3058\u308bSARS-CoV-2 Spike\u306b\u5bfe\u3059\u308b\u53cd\u5fdc\u6027\u3092\u6709\u3059\u308b\u6297\u4f53\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001 \u6700\u8fd1\u306e\u7814\u7a76\u3067\u306f\u3001\u5b50\u4f9b\u3084\u9752\u5e74\u671f\u306e\u4eba\u3005\u304b\u3089\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u4ee5\u524d\u306b\u5f97\u3089\u308c\u8840\u6e05\u3067\u3082\u3001\u3042\u308b\u5272\u5408\u3067SARS-CoV-2 Spike\u306b\u53cd\u5fdc\u6027\u3092\u793a\u3059\u6297\u4f53\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u4e0b\u8a18\u306e\u7814\u7a76\u8ad6\u6587\u3092\u53c2\u7167\u306e\u3053\u3068\uff09\u3002<br \/>\n<a href=\"https:\/\/science.sciencemag.org\/content\/370\/6522\/1339.long\">Preexisting immunity to SARS-CoV-2 before the pandemic<\/a><\/p>\n<p>SARS-CoV-2\/HKU1-CoV \u306b\u4ea4\u5dee\u53cd\u5fdc\u6027\u3092\u793a\u3057\u305f\u6297\u4f53\u306f\u3001SARS-CoV-2\u306eS1\u30c9\u30e1\u30a4\u30f3\u306b\u306f\u30a8\u30d4\u30c8\u30fc\u30d7\u3092\u6301\u305f\u305a\u3001\u3088\u308a\u69cb\u9020\u304c\u4fdd\u5b58\u3055\u308c\u3066\u3044\u308bS2\u30c9\u30e1\u30a4\u30f3\u306b\u30a8\u30d4\u30c8\u30fc\u30d7\u3092\u6301\u3064\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u307e\u305f\u975e\u5e38\u306b\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001SARS-CoV-2\u306b\u611f\u67d3\u3059\u308b\u3068HCoV-HKU1 Spike\u306b\u5bfe\u3059\u308b\u6297\u4f53\u529b\u4fa1\u304c\u4e0a\u6607\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\uff08\u4ed6\u306eHCoVs\u306b\u5bfe\u3057\u3066\u306f\u305d\u308c\u307b\u3069\u3067\u3082\u306a\u3044\u3088\u3046\u3067\u3059\uff09\u3002\u3053\u306e\u3053\u3068\u306f\u3001SARS-CoV-2\u306e\u611f\u67d3\u304c\u3001HCoV-HKU1 Spike\u306b\u7279\u7570\u7684\u306a\u30e1\u30e2\u30ea\u30fcB-\u7d30\u80de\u306e\u6d3b\u6027\u3092\u9ad8\u3081\u305f\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/crossreactivity_coronavirus.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/crossreactivity_coronavirus-300x211.png\" alt=\"\" width=\"300\" height=\"211\" class=\"alignleft size-medium wp-image-3896\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/crossreactivity_coronavirus-300x211.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/crossreactivity_coronavirus-600x422.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/crossreactivity_coronavirus-1024x721.png 1024w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/crossreactivity_coronavirus-768x541.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/crossreactivity_coronavirus.png 1301w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scripps Research Institute\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u3068\u5b63\u7bc0\u6027\u306e\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08HCoVs\uff09\u306e\u9593\u306b\u5b58\u5728\u3059\u308b\u4ea4\u5dee\u53cd\u5fdc\u8840\u6e05\u3068\u30e1\u30e2\u30ea\u30fcB\u7d30\u80de\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002 <\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars-cov-2%ef%bc%89%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e4%ba%a4%e5%b7%ae%e5%8f%8d%e5%bf%9c%e8%a1%80\/\" 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