{"id":3653,"date":"2021-05-12T14:22:49","date_gmt":"2021-05-12T05:22:49","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3645"},"modified":"2021-05-12T16:17:04","modified_gmt":"2021-05-12T07:17:04","slug":"increased-risk-of-sars-cov-2-infection-in-diabetes-mellitus-patients-would-be-related-to-the-increased-expression-levels-of-ace2","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/increased-risk-of-sars-cov-2-infection-in-diabetes-mellitus-patients-would-be-related-to-the-increased-expression-levels-of-ace2\/","title":{"rendered":"Increased risk of SARS-CoV-2 infection in Diabetes Mellitus patients would be related to the increased expression levels of ACE2\u00a0"},"content":{"rendered":"<p>A group from University of Campania L. Vanvitelli, Naples, Italy has reported the relationship between expression levels of ACE2 and increased risks of SARS-CoV-2 infection to cardiomyocytes due to Diabetes Mellitus<br \/>\n<a href=\"https:\/\/cardiab.biomedcentral.com\/articles\/10.1186\/s12933-021-01286-7\">https:\/\/cardiab.biomedcentral.com\/articles\/10.1186\/s12933-021-01286-7<\/a><\/p>\n<p>Comparing diabetes mellitus (DM) patients and healthy individuals, the expression levels of ACE2 and TMPRSS2 were higher in DM patients than non-DM individuals significantly (see a figure below).<br \/>\nFurther, comparing COVID-19 patients and non-COVID-19 individuals, the expression levels of ACE2 and TMPRSS2 were much higher in COVID-19 patients.<br \/>\nAs a result, the increased risk of SARS-CoV-2 infection in DM patients would be related to the increased expression levels of ACE2.<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycosylatedACE2_COVID-19.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycosylatedACE2_COVID-19-300x272.png\" alt=\"\" width=\"300\" height=\"272\" class=\"alignleft size-medium wp-image-3648\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycosylatedACE2_COVID-19-300x272.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycosylatedACE2_COVID-19-600x543.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/GlycosylatedACE2_COVID-19.png 719w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from University of Campania L. Vanvitelli, Naples, Italy has reported the relationship between express<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/increased-risk-of-sars-cov-2-infection-in-diabetes-mellitus-patients-would-be-related-to-the-increased-expression-levels-of-ace2\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-3653","post","type-post","status-publish","format-standard","hentry","category-nature-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=3653"}],"version-history":[{"count":2,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3653\/revisions"}],"predecessor-version":[{"id":3655,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3653\/revisions\/3655"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=3653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=3653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=3653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}