{"id":3583,"date":"2021-05-08T12:17:09","date_gmt":"2021-05-08T03:17:09","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3583"},"modified":"2021-08-04T05:53:13","modified_gmt":"2021-08-03T20:53:13","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19%ef%bc%89%e3%81%ab%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%e3%81%a8%e7%b3%96%e9%8e%96%e3%81%ae%e7%9b%b8","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19%ef%bc%89%e3%81%ab%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%e3%81%a8%e7%b3%96%e9%8e%96%e3%81%ae%e7%9b%b8\/","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306b\u30ec\u30af\u30c1\u30f3\u3068\u7cd6\u9396\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u751f\u304b\u3057\u3066\u7acb\u5411\u304b\u3046"},"content":{"rendered":"<p>Universidade CEUMA, Brazil\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u3092\u6301\u3064\u30a6\u30a4\u30eb\u30b9\u3068\u306e\u6226\u3044\u306b\u7cd6\u9396\u3068\u30ec\u30af\u30c1\u30f3\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u7528\u3044\u305f\u904e\u53bb\u306e\u4e8b\u4f8b\u3092\u30ec\u30d3\u30e5\u30fc\u3057\u3001SARS-CoV-2\u3078\u306e\u6311\u6226\u306b\u89e6\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/academic.oup.com\/glycob\/article\/31\/4\/358\/5934657\">https:\/\/academic.oup.com\/glycob\/article\/31\/4\/358\/5934657<\/a><\/p>\n<p>COVID-19\u306b\u7acb\u3061\u5411\u304b\u3046\u306b\u969b\u3057\u3066\u3001\u30a6\u30a4\u30eb\u30b9\u30fb\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u306e\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b58\u5728\u306f\u3001\u30ec\u30af\u30c1\u30f3\u3092\u7528\u3044\u308b\u65b9\u6cd5\u306b\u3064\u3044\u3066\u3001\u3044\u308d\u3044\u308d\u306a\u53ef\u80fd\u6027\u3092\u4e0e\u3048\u3066\u304f\u308c\u307e\u3059\u3002<strong>\u30ec\u30af\u30c1\u30f3\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u30fb\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u306e\u7cd6\u9396\u3068\u7d50\u5408\u3057\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u5bbf\u4e3b\u7d30\u80de\u3078\u306e\u611f\u67d3\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u3044\u3046\u610f\u5473\u306b\u304a\u3044\u3066\u3001\u65b0\u3057\u3044\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u306e\u958b\u767a\u306e\u30ea\u30fc\u30c9\u9ad8\u5206\u5b50\u306b\u306a\u308a\u5f97\u307e\u3059<\/strong>\u3002<\/p>\n<p>SARS-CoV-2\u306e\u7cd6\u9396\u4fee\u98fe\u306e\u6982\u8981\u306f\u6b21\u306e\u3088\u3046\u3067\u3059\u3002SARS-CoV-2\u306espike\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u306f\u300122\u500b\u306eN-\u578b\u7cd6\u9396\u4fee\u98fe\u90e8\u4f4d\u30016\u500b\u306eO-\u578b\u7cd6\u9396\u4fee\u98fe\u90e8\u4f4d\u304c\u3042\u308a\u307e\u3059\u3002 oligomannose-\u578b\u306e\u7cd6\u9396\u306f\u30012\u30b1\u6240\uff08N234 and N709\uff09\u3001\u8907\u5408\u578b\u7cd6\u9396\u306f\u3001\u4e3b\u306b14\u30b1\u6240\uff08N17, N74, N149, N165, N282, N331, N343, N616, N657, N1098, N1134, N1158, N1173 and N1194\uff09\u3001\u66f4\u306b6\u30f6\u6240\u306f\u3001oligomannose-\u578b\u3068\u8907\u5408\u578b\u304c\u6df7\u5728\u3057\u3066\u3044\u307e\u3059\uff08N61, N122, N603, N717, N801, N1074\uff09\u3002\u6700\u3082\u666e\u901a\u306b\u307f\u3089\u308c\u308boligomannose-\u578b\u7cd6\u9396\u306f\u3001 Man<sub>5<\/sub>GlcNAc<sub>2<\/sub>\u3067\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3001O-\u578b\u7cd6\u9396\u306f\u77ed\u9396\u306b\u3066\u3001Tn\u3084core1\u69cb\u9020\u304c\u4e3b\u3067\u3042\u308a\u307e\u3059\uff08T73, T76, T478, T676, T678, T1076\uff09\u3002<\/p>\n<p>\u3053\u306e\u30ec\u30d3\u30e5\u30fc\u8ad6\u6587\u3067\u89e6\u308c\u3089\u308c\u3066\u3044\u308b\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u3068\u3057\u3066\u8a55\u4fa1\u3055\u308c\u305f<strong>\u5178\u578b\u7684\u306a\u30ec\u30af\u30c1\u30f3\u306f\uff08FRAIL, GRFT, Cyanovirin-N, BanLec, MVN, Avaren\uff09<\/strong>\u3067\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30ec\u30af\u30c1\u30f3\u306e\u7cd6\u9396\u7d50\u5408\u7279\u7570\u6027\u306f\u3001\u307b\u3068\u3093\u3069\u304coligo\u53ca\u3073 high mannose\u3067\u3042\u308a\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u904e\u53bb\u306b\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3055\u308c\u305f\u30a6\u30a4\u30eb\u30b9\uff08HIV, HCV, influenza, Ebora\uff09\u306e\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u306f\u3001\u5f37\u304fmannose\u4fee\u98fe\u3092\u53d7\u3051\u3066\u3044\u305f\u3053\u3068\u306b\u95a2\u4fc2\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u30a6\u30a4\u30eb\u30b9\u306b\u6bd4\u8f03\u3059\u308b\u3068\u3001SARS-CoV-2\u306e\u7cd6\u9396\u4fee\u98fe\u306f\u5e7e\u3089\u304b\u30d1\u30bf\u30fc\u30f3\u304c\u7570\u306a\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3057\u3001\u5f93\u3063\u3066\u3001\u3053\u308c\u3089\u306e\u30ec\u30af\u30c1\u30f3\u4ee5\u5916\u306b\u3001SARS-CoV-2\u3068\u6226\u3046\u306b\u306f\u3088\u308a\u512a\u308c\u305f\u30ec\u30af\u30c1\u30f3\u304c\u5b58\u5728\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u3068\u3082\u3042\u308c\u3001<strong>\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u3068\u3057\u3066\u30ec\u30af\u30c1\u30f3\u3092\u4f7f\u3046\u5834\u5408\u306e\u5927\u304d\u306a\u5236\u9650\u306f\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u4ee5\u5916\u306e\u671b\u307e\u3057\u304f\u306a\u3044\u4f53\u7d30\u80de\u306b\u7d50\u5408\u3057\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u3053\u3068<\/strong>\u306b\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30ec\u30af\u30c1\u30f3\u3092\u6295\u4e0e\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u51dd\u96c6\u53cd\u5fdc<\/strong>\u3084<strong>\u7d30\u80de\u5897\u6b96<\/strong>\u3092\u62db\u3044\u3066\u3057\u307e\u3046\u3068\u3044\u3046\u3088\u3046\u306a\u4e8b\u67c4\u304c\u3042\u308a\u307e\u3059\u3002\u5f93\u3063\u3066\u3001\u30ec\u30af\u30c1\u30f3\u3092\u4f7f\u3046\u3053\u3068\u306b\u3088\u308b\u305d\u3046\u3044\u3063\u305f\u526f\u4f5c\u7528\u3092\u6291\u3048\u306a\u304c\u3089\u3001SARS-CoV-2\u306b\u5bfe\u3059\u308b\u7279\u7570\u7684\u306a\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u3068\u3057\u3066\u306e\u307f\u50cd\u304f\u3088\u3046\u306b\u30ec\u30af\u30c1\u30f3\u3092\u30bf\u30f3\u30d1\u30af\u8cea\u5de5\u5b66\u3092\u7528\u3044\u3066\u5de5\u592b\u3057\u3066\u3084\u308b\u3053\u3068\u304c\u5fc5\u8981\u3067\u3059\u3002\u304a\u305d\u3089\u304f\u305d\u306e\u30ad\u30fc\u30ef\u30fc\u30c9\u306f\u3001\u878d\u5408\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f5c\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\u4f8b\u3048\u3070\u3001Fab\u878d\u5408, Fc\u878d\u5408, PEG\u5316\u3001\u306a\u3069\u306a\u3069\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Universidade CEUMA, Brazil\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u3092\u6301\u3064\u30a6\u30a4\u30eb\u30b9\u3068\u306e\u6226\u3044\u306b\u7cd6\u9396\u3068\u30ec\u30af\u30c1\u30f3\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u7528\u3044\u305f\u904e\u53bb\u306e\u4e8b\u4f8b\u3092\u30ec\u30d3\u30e5\u30fc\u3057\u3001SARS-CoV-2\u3078\u306e\u6311\u6226\u306b\u89e6\u308c\u3066\u3044\u307e\u3059\u3002 https:\/<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19%ef%bc%89%e3%81%ab%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%e3%81%a8%e7%b3%96%e9%8e%96%e3%81%ae%e7%9b%b8\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-3583","post","type-post","status-publish","format-standard","hentry","category-technology-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3583","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=3583"}],"version-history":[{"count":13,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3583\/revisions"}],"predecessor-version":[{"id":5510,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3583\/revisions\/5510"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=3583"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=3583"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=3583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}