{"id":3565,"date":"2021-05-07T08:15:18","date_gmt":"2021-05-06T23:15:18","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3565"},"modified":"2021-06-28T06:52:13","modified_gmt":"2021-06-27T21:52:13","slug":"sars-cov-2%e3%81%aentd%e3%82%92%e3%82%bf%e3%83%bc%e3%82%b2%e3%83%83%e3%83%88%e3%81%a8%e3%81%99%e3%82%8b%e4%b8%ad%e5%92%8c%e6%8a%97%e4%bd%93%e3%81%ae%e7%89%b9%e6%80%a7%e3%81%ab%e3%81%a4%e3%81%84","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/sars-cov-2%e3%81%aentd%e3%82%92%e3%82%bf%e3%83%bc%e3%82%b2%e3%83%83%e3%83%88%e3%81%a8%e3%81%99%e3%82%8b%e4%b8%ad%e5%92%8c%e6%8a%97%e4%bd%93%e3%81%ae%e7%89%b9%e6%80%a7%e3%81%ab%e3%81%a4%e3%81%84\/","title":{"rendered":"SARS-CoV-2\u306eNTD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3059\u308b\u4e2d\u548c\u6297\u4f53\u306e\u7279\u6027\u306b\u3064\u3044\u3066"},"content":{"rendered":"<p>Israel Institute for Biological Research\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306eNTD\u306b\u5bfe\u3059\u308b12\u7a2e\u985e\u306e\u4e2d\u548c\u6297\u4f53\u306e\u7279\u6027\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33937725\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33937725\/<\/a><\/p>\n<p>12\u7a2e\u985e\u306eSARS-CoV-2 NTD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3059\u308b\u6297\u4f53 (BLN1 \uff5e BLN14) \u306f\u52b9\u679c\u7684\u306bSARS-CoV-2\u3092\u4e2d\u548c\u5316\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u305d\u306eIC<sub>50<\/sub>\u306f\u3001\u6700\u3082\u4f4e\u3044\u4e2d\u548c\u6d3b\u6027\u306eBLN8\u306754.9 \u00b5g\/ml\u3001\u6700\u3082\u9ad8\u3044\u4e2d\u548c\u6d3b\u6027\u3092\u793a\u3059BNL1\u3084BLN12\u30670.008 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DC-SIGN\u306a\u3069\uff09\u3082\u611f\u67d3\u53d7\u5bb9\u4f53\u3068\u3057\u3066\u6a5f\u80fd\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u4ee3\u8868\u7684\u306a\u6297\u4f53\u304cSARS-CoV-2\u3068L-SIGN\u306e\u7d50\u5408\u3092\u963b\u5bb3\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u306b\u3064\u3044\u3066\u306e\u5b9f\u9a13\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002 \u963b\u5bb3\u52b9\u7387\u306f\u3001BLN14\u306e25\uff05\u304b\u3089BLN4\u306e50\uff05\u306b\u5206\u5e03\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u963b\u5bb3\u52b9\u679c\u306f\u3001\u6297\u4f53\u306eNTD\u306e\u7cd6\u9396\u306b\u5bfe\u3059\u308b\u76f4\u63a5\u7684\u306a\u7d50\u5408\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001L-SIGN\u3068\u306e\u7acb\u4f53\u969c\u5bb3\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>ACE2\u306e\u767a\u73fe\u304c\u4f4e\u3044\u7d44\u7e54\u306e\u7d30\u80de\u306e\u5834\u5408\u306b\u3001L-SIGN\u3084DC-SIGN\u304cSARS-CoV-2\u306b\u5bfe\u3059\u308b\u7b2c\u4e8c\u306e\u611f\u67d3\u53d7\u5bb9\u4f53\u3068\u306a\u308b\u306e\u3067\u3042\u308c\u3070\u3001NTD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3059\u308b\u6297\u4f53\u304cSARS-CoV-2\u306e\u611f\u67d3\u3092\u6291\u3048\u8fbc\u3080\u305f\u3081\u306b\u6709\u52b9\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3001\u7d50\u679c\u3068\u3057\u3066\u3001RBD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3059\u308b\u6297\u4f53\u3068NTD\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3059\u308b\u30ab\u30af\u30c6\u30eb\u6297\u4f53\u304cSARS-CoV-2\u306e\u6cbb\u7642\u306b\u6709\u52b9\u3067\u3042\u308b\u306f\u305a\u3001\u3068\u7d50\u8ad6\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Israel Institute for Biological Research\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306eNTD\u306b\u5bfe\u3059\u308b12\u7a2e\u985e\u306e\u4e2d\u548c\u6297\u4f53\u306e\u7279\u6027\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/sars-cov-2%e3%81%aentd%e3%82%92%e3%82%bf%e3%83%bc%e3%82%b2%e3%83%83%e3%83%88%e3%81%a8%e3%81%99%e3%82%8b%e4%b8%ad%e5%92%8c%e6%8a%97%e4%bd%93%e3%81%ae%e7%89%b9%e6%80%a7%e3%81%ab%e3%81%a4%e3%81%84\/\" 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