{"id":3525,"date":"2021-05-04T11:02:22","date_gmt":"2021-05-04T02:02:22","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3525"},"modified":"2021-05-04T11:07:43","modified_gmt":"2021-05-04T02:07:43","slug":"%e3%83%88%e3%82%b7%e3%83%aa%e3%82%ba%e3%83%9e%e3%83%96%ef%bc%88tocilizumab%ef%bc%89%e3%81%aecovid-19%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e6%b2%bb%e7%99%82%e5%8a%b9%e6%9e%9c%e3%81%af%e3%80%81il-6","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e3%83%88%e3%82%b7%e3%83%aa%e3%82%ba%e3%83%9e%e3%83%96%ef%bc%88tocilizumab%ef%bc%89%e3%81%aecovid-19%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e6%b2%bb%e7%99%82%e5%8a%b9%e6%9e%9c%e3%81%af%e3%80%81il-6\/","title":{"rendered":"\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\uff08Tocilizumab\uff09\u306eCOVID-19\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u52b9\u679c\u306f\u3001IL-6\uff1e100pg\/mL\u4ee5\u4e0a\u3001\u9178\u7d20\u98fd\u548c\u5ea6\uff1c90%\u306e\u60a3\u8005\u3067\u5287\u7684\u306b\u8868\u308c\u308b"},"content":{"rendered":"<p>Medical University of Bia\u0142ystok, Poland\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\uff08Tocilizumab\uff09\u306eCOVID-19\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u52b9\u679c\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.mdpi.com\/2077-0383\/10\/8\/1583\/htm\">https:\/\/www.mdpi.com\/2077-0383\/10\/8\/1583\/htm<\/a><\/p>\n<p>\u5408\u8a08825\u540d\u306e\u60a3\u8005\u306e\u5185\u3001170\u540d\u306b\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\u304c\u6295\u4e0e\u3055\u308c\u3001655\u540d\u306b\u306f\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\u306f\u52ff\u8ad6\u306e\u3053\u3068\u4ed6\u306e\u5982\u4f55\u306a\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u53d7\u5bb9\u4f53\u306b\u5bfe\u3059\u308b\u963b\u5bb3\u5264\uff08mAb\uff09\u3082\u4f7f\u7528\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\u306e\u30c9\u30fc\u30ba\u306f\u3001\u4e00\u56de\u306e\u6295\u4e0e\u3067\u30018mg\/kg\u306b\u3066\u3001\u6700\u5927\u30c9\u30fc\u30ba\u306f800mg\u3068\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>IL-6\u306e\u30ec\u30d9\u30eb\u304c100pg\/mL\u3088\u308a\u9ad8\u3044\u5834\u5408\u306b\u3001\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\u306e\u9855\u8457\u306a\u52b9\u679c\u304c\u8868\u308c\u3001hazard ratio [HR]=0.21\uff0895% confidence interval [CI]: 0.08\u20130.57)\u3068\u306a\u308a\u307e\u3057\u305f\u3002IL-6\u306e\u30ec\u30d9\u30eb\u304c100 pg\/mL\u3088\u308a\u9ad8\u304f\u3001\u4e14\u3064\u9178\u7d20\u98fd\u548c\u5ea6\u304c90%\u4ee5\u4e0b\u3042\u308b\u3044\u306f\u9178\u7d20\u5438\u5165\u304c\u5fc5\u8981\u306a\u5834\u5408\u3067\u3001\u66f4\u306b\u52b9\u679c\u304c\u9855\u8457\u3068\u306a\u308a\u3001HR=0.18\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u4ed8\u3051\u52a0\u3048\u308b\u306a\u3089\u3070\u3001IL-6\u306e\u6fc3\u5ea6\u304c100pg\/mL\u3088\u308a\u3082\u4f4e\u3044\u5834\u5408\u306b\u306f\u3001\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\u306f\u307b\u3068\u3093\u3069\u52b9\u304b\u306a\u3044\u3068\u3044\u3046\u7d50\u679c\u3067\u3082\u3042\u308a\u307e\u3059\u3002<br \/>\n\u3057\u304b\u3057\u3001\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\u304c\u3069\u306e\u3088\u3046\u306a\u72b6\u614b\u306e\u6642\u306b\u3001\u5982\u4f55\u306a\u308b\u30c9\u30fc\u30ba\u304c\u6700\u9069\u306a\u306e\u304b\uff1f\u3068\u3044\u3046\u77e5\u898b\u304c\u5f97\u3089\u308c\u305f\u3053\u3068\u306f\u975e\u5e38\u306b\u7d20\u6674\u3089\u3057\u3044\u3068\u601d\u308f\u308c\u307e\u3059\u3002 <\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/TOC_COVID-19-1.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/TOC_COVID-19-1-300x115.png\" alt=\"\" width=\"300\" height=\"115\" class=\"alignleft size-medium wp-image-3529\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/TOC_COVID-19-1-300x115.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/TOC_COVID-19-1-600x230.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/05\/TOC_COVID-19-1-1024x393.png 1024w, 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