{"id":3332,"date":"2021-04-21T10:42:54","date_gmt":"2021-04-21T01:42:54","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3332"},"modified":"2021-04-21T10:42:54","modified_gmt":"2021-04-21T01:42:54","slug":"covid-19%e6%b2%bb%e7%99%82%e8%96%ac%e3%81%a8%e3%81%97%e3%81%a6%e3%81%ae%e3%83%87%e3%82%ad%e3%82%b5%e3%83%a1%e3%82%bf%e3%82%be%e3%83%b3%ef%bc%88dexamethasone%ef%bc%89%e3%81%ae%e5%83%8d%e3%81%8d","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/covid-19%e6%b2%bb%e7%99%82%e8%96%ac%e3%81%a8%e3%81%97%e3%81%a6%e3%81%ae%e3%83%87%e3%82%ad%e3%82%b5%e3%83%a1%e3%82%bf%e3%82%be%e3%83%b3%ef%bc%88dexamethasone%ef%bc%89%e3%81%ae%e5%83%8d%e3%81%8d\/","title":{"rendered":"COVID-19\u6cbb\u7642\u85ac\u3068\u3057\u3066\u306e\u30c7\u30ad\u30b5\u30e1\u30bf\u30be\u30f3\uff08Dexamethasone\uff09\u306e\u50cd\u304d\u306b\u3064\u3044\u3066"},"content":{"rendered":"<p>\u539a\u751f\u52b4\u50cd\u7701\u306f\u30012020\u5e745\u6708\u306b\u7279\u4f8b\u3067\u627f\u8a8d\u3057\u305f\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u300c\u30ec\u30e0\u30c7\u30b7\u30d3\u30eb\u300d\u306b\u7d9a\u304d\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u85ac\u306e\u300c\u30c7\u30ad\u30b5\u30e1\u30bf\u30be\u30f3\u300d\u3092\u30012020\u5e747\u6708\u306b\u65e5\u672c\u56fd\u5185\u3067\u627f\u8a8d\u3055\u308c\u3066\u3044\u308bCOVID-19\u306e\u533b\u85ac\u54c1\u3068\u3057\u3066\u8ffd\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u30c7\u30ad\u30b5\u30e1\u30bf\u30be\u30f3\u304c\u3069\u3093\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u304b\uff1f\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u308b\u8ad6\u6587\u3092\u3054\u7d39\u4ecb\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>University of Huddersfield, UK\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306e\u7814\u7a76\u5831\u544a\u3067\u3059\u3002<br \/>\n<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s10753-021-01464-5\">https:\/\/link.springer.com\/article\/10.1007\/s10753-021-01464-5<\/a><\/p>\n<p>PBMC\uff08\u672b\u68a2\u8840\u5358\u6838\u7d30\u80de\uff09\u3092SARS-CoV-2 Spike\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u523a\u6fc0\u3057\u305f\u5834\u5408\u306b\u306f\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3067\u3042\u308bTNF\u03b1, IL-6, IL-1\u03b2 and IL-8\u3089\u304c\u9ad8\u767a\u73fe\u3057\u307e\u3059\u3002\u30c7\u30ad\u30b5\u30e1\u30bf\u30be\u30f3\uff08100nM\uff09\u3092\u7528\u3044\u3066PBMC\u3092\u524d\u51e6\u7406\u3059\u308b\u3068\u3001\u3053\u308c\u3089\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u7523\u751f\u304c\u5927\u5e45\u306b\u6291\u5236\u3055\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002NF-\u03baB\u8ee2\u5199\u56e0\u5b50\u3001p38 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