{"id":3250,"date":"2021-04-15T09:41:16","date_gmt":"2021-04-15T00:41:16","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3250"},"modified":"2021-07-21T23:19:00","modified_gmt":"2021-07-21T14:19:00","slug":"dectin-2%e3%81%8c%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e3%81%ae%e6%84%9f%e6%9f%93%e3%81%ab%e9%96%a2%e3%82%8f%e3%81%a3%e3%81%a6%e3%81%84","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/dectin-2%e3%81%8c%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e3%81%ae%e6%84%9f%e6%9f%93%e3%81%ab%e9%96%a2%e3%82%8f%e3%81%a3%e3%81%a6%e3%81%84\/","title":{"rendered":"Dectin-2\u304c\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306e\u611f\u67d3\u306b\u95a2\u308f\u3063\u3066\u3044\u305f"},"content":{"rendered":"

\u65b0\u6f5f\u5927\u5b66\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306e\u611f\u67d3\u3068\u708e\u75c7\u6027\u514d\u75ab\u5fdc\u7b54\u306bDectin-2\u304c\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/www.jstage.jst.go.jp\/article\/biomedres\/42\/2\/42_53\/_pdf\/-char\/en<\/a><\/p>\n

\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3068\u8a00\u3048\u3070\u3001\u30a6\u30a4\u30eb\u30b9\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u306b\u5b58\u5728\u3059\u308bhemagglutinin (HA)\u3068\u30b7\u30a2\u30eb\u9178\u3068\u306e\u95a2\u4fc2\u6027\u304c\u91cd\u8981\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u306b\u7d61\u3080\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u306f\u75c7\u72b6\u304c\u73fe\u308c\u3066\u304b\u308948\u6642\u9593\u4ee5\u5185\u306b\u6295\u4e0e\u3057\u306a\u3044\u3068\u3042\u307e\u308a\u52b9\u679c\u7684\u3067\u306f\u306a\u3044\u3068\u3055\u308c\u307e\u3059\u3002\u6297\u539f\u63d0\u793a\u7d30\u80de\u3067\u3042\u308b\u6a39\u72b6\u7d30\u80de\u3084\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306f\u3001\u75c5\u539f\u83cc\u3084\u6b7b\u7d30\u80de\u3089\u306b\u7279\u6709\u306a\u5206\u5b50\u30d1\u30bf\u30fc\u30f3\u3092\u8a8d\u8b58\u3057\u3001\u514d\u75ab\u3092\u6d3b\u6027\u5316\u3057\u307e\u3059\u304c\u3001\u3053\u306e\u3088\u3046\u306a\u30d1\u30bf\u30fc\u30f3\u8a8d\u8b58\u53d7\u5bb9\u4f53\u306b\u306f\u3001Toll-like receptors (TLRs), Nod-like receptors (NLRs), C-type lectin receptors (CLRs)\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

HA\u306fhigh mannose\u578b\u306e\u7cd6\u9396\u4fee\u98fe\u3082\u5f37\u304f\u53d7\u3051\u3066\u3044\u307e\u3059\u306e\u3067\u3001C-type Lectin\u304cHA\u306e\u7cd6\u9396\u4fee\u98fe\u3092\u8a8d\u8b58\u3059\u308b\u3053\u3068\u3067\u3001\u514d\u75ab\u53cd\u5fdc\u304c\u6d3b\u6027\u5316\u3055\u308c\u308b\u3068\u3044\u3046\u30b7\u30b0\u30ca\u30eb\u30d1\u30b9\u3082\u5fc5\u305a\u3084\u5b58\u5728\u3059\u308b\u306f\u305a\u3067\u3059\u3002C-type Lectin family\u306b\u306f\u3001DC-SIGN, Dectin-1, Dectin-2, Mincle\u306a\u3069\u304c\u542b\u307e\u308c\u307e\u3059\u304c\u3001\u8457\u8005\u3089\u306f\u3001\u6a39\u72b6\u7d30\u80de\u306b\u767a\u73fe\u3059\u308bDectin-2\u304cA\u578b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3084B\u578b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306eHA\u3092\u8a8d\u8b58\u3057\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u7523\u751f\u3092\u4fc3\u3059\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002Dectin-2\u306f\u3001high mannose polysaccharides\u3092\u8a8d\u8b58\u3059\u308b\u3068\u3055\u308c\u307e\u3059\u3002
\n\u4e0b\u56f3\u306f\u3001Dectin-2\u3092KO\u3059\u308b\u3053\u3068\u3067\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u7523\u751f\u304c\u5927\u304d\u304f\u6291\u5236\u3055\u308c\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\u65b0\u6f5f\u5927\u5b66\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306e\u611f\u67d3\u3068\u708e\u75c7\u6027\u514d\u75ab\u5fdc\u7b54\u306bDectin-2\u304c\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/www.jstage.jst.go.jp\/article\/biomedres\/4<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-3250","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3250","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=3250"}],"version-history":[{"count":11,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3250\/revisions"}],"predecessor-version":[{"id":5106,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3250\/revisions\/5106"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=3250"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=3250"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=3250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}