{"id":3171,"date":"2021-04-10T06:59:24","date_gmt":"2021-04-09T21:59:24","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=3171"},"modified":"2021-04-10T06:59:24","modified_gmt":"2021-04-09T21:59:24","slug":"il-1r7-%e6%8a%97%e4%bd%93%e3%81%8ccovid-19%e3%81%ae%e6%b2%bb%e7%99%82%e8%96%ac%e3%81%a8%e3%81%97%e3%81%a6%e6%9c%89%e5%8a%b9%e3%81%8b%e3%82%82%e3%81%97%e3%82%8c%e3%81%aa%e3%81%84","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/il-1r7-%e6%8a%97%e4%bd%93%e3%81%8ccovid-19%e3%81%ae%e6%b2%bb%e7%99%82%e8%96%ac%e3%81%a8%e3%81%97%e3%81%a6%e6%9c%89%e5%8a%b9%e3%81%8b%e3%82%82%e3%81%97%e3%82%8c%e3%81%aa%e3%81%84\/","title":{"rendered":"IL-1R7 \u6297\u4f53\u304cCOVID-19\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u6709\u52b9\u304b\u3082\u3057\u308c\u306a\u3044"},"content":{"rendered":"<p>University of Colorado Denver Anschutz Medical Campus\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066IL-1R7\u6297\u4f53\u3092\u63d0\u6848\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(21)00416-6\/fulltext\">https:\/\/www.jbc.org\/article\/S0021-9258(21)00416-6\/fulltext<\/a><\/p>\n<p>\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u304c\u7570\u5e38\u306b\u6d3b\u6027\u5316\uff08MAS:\u3000Macrophage Activated Syndrome\uff09\u3059\u308b\u3068\u3001\u81f4\u6b7b\u7387\u306e\u9ad8\u3044\u91cd\u75c7\u306b\u9665\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306e\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u304c\u307e\u3055\u306b\u305d\u306e\u5178\u578b\u3067\u3059\u3002<br \/>\nIL-1\u30d5\u30a1\u30df\u30ea\u30fc\u306b\u5c5e\u3059\u308bInterleukin-18 (IL-18)\u304c\u3001MAS\u3084COVID-19\u3067\u9ad8\u767a\u73fe\u3057\u3001\u305d\u306e\u30ec\u30d9\u30eb\u304c\u91cd\u75c7\u5ea6\u3068\u76f8\u95a2\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>IL-18 \u306f\u3001 IL-1 Receptor 5 (IL-1R5, IL-18 Receptor alpha chain)\u306b\u7d50\u5408\u3057\u3001\u5171\u53d7\u5bb9\u4f53\u3067\u3042\u308b IL-1 Receptor 7 (IL-1R7, IL-18 Receptor beta chain)\u3082\u30ea\u30af\u30eb\u30fc\u30c8\u3057\u307e\u3059\u3002<br \/>\n\u8457\u8005\u3089\u306f\u3001IL-1R7\u6297\u4f53\u304cIL-18\u306b\u3088\u3063\u3066\u4ecb\u5728\u3055\u308c\u308b NF\u03baB \u306e\u6d3b\u6027\u5316\u3001IFN\u03b3\u306e\u7523\u751f\u3001\u305d\u3057\u3066 IL-6\u306e\u7523\u751f\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/04\/anti-IL-1R7_IL-6_COVID-19.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-3173\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/04\/anti-IL-1R7_IL-6_COVID-19-300x202.png\" alt=\"\" width=\"300\" height=\"202\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/04\/anti-IL-1R7_IL-6_COVID-19-300x202.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/04\/anti-IL-1R7_IL-6_COVID-19-272x182.png 272w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/04\/anti-IL-1R7_IL-6_COVID-19.png 540w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of Colorado Denver Anschutz Medical Campus\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001COVID-19\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066IL-1R7\u6297\u4f53\u3092\u63d0\u6848\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/www.jbc.o<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/il-1r7-%e6%8a%97%e4%bd%93%e3%81%8ccovid-19%e3%81%ae%e6%b2%bb%e7%99%82%e8%96%ac%e3%81%a8%e3%81%97%e3%81%a6%e6%9c%89%e5%8a%b9%e3%81%8b%e3%82%82%e3%81%97%e3%82%8c%e3%81%aa%e3%81%84\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-3171","post","type-post","status-publish","format-standard","hentry","category-technology-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=3171"}],"version-history":[{"count":2,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3171\/revisions"}],"predecessor-version":[{"id":3174,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3171\/revisions\/3174"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=3171"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=3171"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=3171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}