{"id":3023,"date":"2021-03-24T19:56:12","date_gmt":"2021-03-24T10:56:12","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=3023"},"modified":"2021-07-21T23:22:13","modified_gmt":"2021-07-21T14:22:13","slug":"%e3%82%ab%e3%83%b3%e3%82%b8%e3%83%80%e3%83%bb%e3%82%a2%e3%83%ab%e3%83%93%e3%82%ab%e3%83%b3%e3%82%b9%e3%81%ae%e7%b4%b0%e8%83%9e%e8%86%9c%e4%b8%8a%e3%81%aen%e5%9e%8b%e7%b3%96%e9%8e%96%ef%bc%88mannose-co","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e3%82%ab%e3%83%b3%e3%82%b8%e3%83%80%e3%83%bb%e3%82%a2%e3%83%ab%e3%83%93%e3%82%ab%e3%83%b3%e3%82%b9%e3%81%ae%e7%b4%b0%e8%83%9e%e8%86%9c%e4%b8%8a%e3%81%aen%e5%9e%8b%e7%b3%96%e9%8e%96%ef%bc%88mannose-co\/","title":{"rendered":"\u30ab\u30f3\u30b8\u30c0\u30fb\u30a2\u30eb\u30d3\u30ab\u30f3\u30b9\u306e\u7d30\u80de\u819c\u4e0a\u306eN\u578b\u7cd6\u9396\uff08mannose core\uff09\u304c\u6557\u8840\u75c7\u306b\u304a\u3044\u3066\u6297\u708e\u75c7\u7684\u306b\u4f5c\u7528\u3059\u308b"},"content":{"rendered":"<p>\u4eac\u90fd\u5927\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30ab\u30f3\u30b8\u30c0\u30fb\u30a2\u30eb\u30d3\u30ab\u30f3\u30b9\u306e\u7d30\u80de\u819c\u4e0a\u306eN\u578b\u7cd6\u9396(mannose core\uff09\u304c\u6297\u708e\u75c7\u7684\u306b\u50cd\u304f\u3053\u3068\u3092\u6557\u8840\u75c7\u306b\u3066\u5b9f\u8a3c\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.nature.com\/articles\/s42003-021-01870-3\">https:\/\/www.nature.com\/articles\/s42003-021-01870-3<\/a><\/p>\n<p>Lipopolysaccharide\uff08LPS\uff09\u3092\u7528\u3044\u3066\u30de\u30a6\u30b9\u306b\u6557\u8840\u75c7\u3092\u8a98\u8d77\u3057\u3001\u30ab\u30f3\u30b8\u30c0\u30fb\u30a2\u30eb\u30d3\u30ab\u30f3\u30b9\uff08J-1020\u682a\uff09\u306e\u7d30\u80de\u819c\u4e0a\u306eN\u578b\u7cd6\u9396\uff08\u30de\u30f3\u30ce\u30fc\u30b9\u69cb\u9020\uff09\u304c\u6297\u708e\u75c7\u7684\u306b\u50cd\u304f\u3053\u3068\u3092\u5b9f\u8a3c\u3057\u3066\u3044\u307e\u3059\u3002J-1020\u304b\u3089\u30de\u30f3\u30ce\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u62bd\u51fa\u3057\u3001LPS\u306b\u3066\u6557\u8840\u75c7\u3092\u8d77\u3053\u3057\u3066\u3044\u308b\u30de\u30a6\u30b9\u306b\u6295\u4e0e\u3059\u308b\u3068\u751f\u5b58\u7387\u304c\u5287\u7684\u306b\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u6642\u306b\u3001\u6297\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3067\u3042\u308bIL-10\u3089\u304cJ-1020\u306e\u6295\u4e0e\u3067\u9ad8\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002J-1020\u306e\u30de\u30f3\u30ce\u30bf\u30f3\u30d1\u30af\u8cea\u304cC-Type Lectin\u3067\u3042\u308bDectin-2\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u3053\u306e\u4e00\u9023\u306e\u73fe\u8c61\u304c\u8d77\u304d\u3066\u3044\u308b\u3089\u3057\u3044\u3053\u3068\u3082\u78ba\u304b\u3081\u3089\u308c\u307e\u3057\u305f\u3002Dectin-2\u3092KO\u3059\u308b\u3068\u3001\u751f\u5b58\u7387\u306f\u6025\u6e1b\u3057\u3001J-1020\u3092\u6295\u4e0e\u3057\u3066\u3082IL-10\u306e\u5206\u6ccc\u306f\u4e0a\u6607\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u307e\u305f\u3001Dectin-2\u3068\u7279\u7570\u7684\u306b\u76f8\u4e92\u4f5c\u7528\u3059\u308bN\u578b\u7cd6\u9396\u306e\u69cb\u9020\u306f\u3001mannose core\u3067\u3042\u308b\u3089\u3057\u304d\u3053\u3068\u3082\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/C.-albicans_LPS_Dectin-2.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/C.-albicans_LPS_Dectin-2.png\" alt=\"\" width=\"853\" height=\"510\" class=\"alignleft size-full wp-image-3029\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/C.-albicans_LPS_Dectin-2.png 853w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/C.-albicans_LPS_Dectin-2-600x359.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/C.-albicans_LPS_Dectin-2-300x179.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/C.-albicans_LPS_Dectin-2-768x459.png 768w\" sizes=\"auto, (max-width: 853px) 100vw, 853px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4eac\u90fd\u5927\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30ab\u30f3\u30b8\u30c0\u30fb\u30a2\u30eb\u30d3\u30ab\u30f3\u30b9\u306e\u7d30\u80de\u819c\u4e0a\u306eN\u578b\u7cd6\u9396(mannose core\uff09\u304c\u6297\u708e\u75c7\u7684\u306b\u50cd\u304f\u3053\u3068\u3092\u6557\u8840\u75c7\u306b\u3066\u5b9f\u8a3c\u3057\u3066\u3044\u307e\u3059\u3002 https:\/\/www.nature.com\/articles\/s42003-<\/p><\/div>\n<div 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class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-3023","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3023","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=3023"}],"version-history":[{"count":13,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3023\/revisions"}],"predecessor-version":[{"id":5115,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/3023\/revisions\/5115"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=3023"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=3023"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=3023"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}