{"id":2982,"date":"2021-03-20T09:06:22","date_gmt":"2021-03-20T00:06:22","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=2979"},"modified":"2021-03-22T13:31:57","modified_gmt":"2021-03-22T04:31:57","slug":"o-glycan-analysis-of-the-new-coronavirus-sars-cov-2","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/o-glycan-analysis-of-the-new-coronavirus-sars-cov-2\/","title":{"rendered":"O-glycan analysis of the new coronavirus (SARS-CoV-2)"},"content":{"rendered":"<p>A group from University of Wisconsin-Madison, etc. has reported on the analysis of O-glycans expressed on the new coronavirus (SARS-CoV-2).<br \/>\n<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.02.28.433291v1\">https:\/\/www.biorxiv.org\/content\/10.1101\/2021.02.28.433291v1<\/a><\/p>\n<p>In order to analyze O-glycans, N-glycans on SARS-CoV-2 spike protein expressed with HEK293 were removed by PNGase F treatment. Authors combined ion mobility spectrometry (TIMS) and ultrahigh-resolution Fourier transform ion cyclotron resonance (FTICR) MS analysis.<br \/>\nAs a result, it was found that the majority of the O-glycan modification was Sialyl-T-antigen.<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/O-glycan_SARS-CoV-2.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/O-glycan_SARS-CoV-2-1024x536.png\" alt=\"\" width=\"696\" height=\"364\" class=\"alignleft size-large wp-image-2980\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/O-glycan_SARS-CoV-2-1024x536.png 1024w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/O-glycan_SARS-CoV-2-600x314.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/O-glycan_SARS-CoV-2-300x157.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/O-glycan_SARS-CoV-2-768x402.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/O-glycan_SARS-CoV-2.png 1062w\" sizes=\"auto, (max-width: 696px) 100vw, 696px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from University of Wisconsin-Madison, etc. has reported on the analysis of O-glycans expressed on the <\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/o-glycan-analysis-of-the-new-coronavirus-sars-cov-2\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-2982","post","type-post","status-publish","format-standard","hentry","category-nature-en"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - 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