{"id":2870,"date":"2021-03-13T08:11:59","date_gmt":"2021-03-12T23:11:59","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=2870"},"modified":"2021-07-21T23:25:36","modified_gmt":"2021-07-21T14:25:36","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19%ef%bc%89%e3%81%aeicu%e6%82%a3%e8%80%85%e3%81%ab%e8%a6%8b%e3%82%89%e3%82%8c%e3%82%8b%e7%89%b9%e7%95%b0","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19%ef%bc%89%e3%81%aeicu%e6%82%a3%e8%80%85%e3%81%ab%e8%a6%8b%e3%82%89%e3%82%8c%e3%82%8b%e7%89%b9%e7%95%b0\/","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306eICU\u60a3\u8005\u306b\u898b\u3089\u308c\u308b\u7279\u7570\u7684\u306a\u30de\u30fc\u30ab\u30fc\u306b\u3064\u3044\u3066\uff1a\u8840\u7ba1\u5185\u76ae\u304c\u5927\u304d\u304f\u640d\u50b7\u3092\u53d7\u3051\u3066\u3044\u308b"},"content":{"rendered":"

University of Ferrara\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306b\u3066\u6025\u6027\u547c\u5438\u4e0d\u5168\uff08ARDS\uff09\u3092\u767a\u75c7\u3057ICU\u6cbb\u7642\u3092\u53d7\u3051\u3056\u308b\u3092\u5f97\u306a\u304f\u306a\u3063\u305f\u60a3\u8005\u3068\u3001\u305d\u306e\u4ed6\u5f93\u6765\u306eARDS\u60a3\u8005\u3068\u306e\u9593\u306b\u304a\u3051\u308b\u30de\u30fc\u30ab\u30fc\u306e\u9055\u3044\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/ccforum.biomedcentral.com\/articles\/10.1186\/s13054-021-03499-4<\/a><\/p>\n

\u7d42\u672b\u7cd6\u5316\u7523\u7269\u53d7\u5bb9\u4f53\uff08RAGE\uff09\u3001Angiopoietin-2 (Ang-2)\u3001\u53ef\u6eb6\u6027intercellular adhesion molecule-1 (ICAM-1)\u3001\u53ef\u6eb6\u6027vascular cell adhesion molecule-1 (VCAM-1)\u3001E-Selectin\u3001P-Selectin\u304c\u6bd4\u8f03\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u30a2\u30f3\u30b8\u30aa\u30dd\u30a8\u30c1\u30f3\u306f\u3001\u8108\u7ba1\u5f62\u6210\u3042\u308b\u3044\u306f\u8840\u7ba1\u65b0\u751f\u3092\u4fc3\u9032\u3059\u308b\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308a\u6210\u9577\u56e0\u5b50\u3001
\nICAM-1\u306f\u3001\u514d\u75ab\u7cfb\u306e\u7d30\u80de\u9593\u76f8\u4e92\u4f5c\u7528\u3092\u53f8\u308b\u63a5\u7740\u5206\u5b50\u306e\u4e00\u3064\u3067\u3042\u308a\u3001\u6d3b\u6027\u5316\u30ea\u30f3\u30d1\u7403\u306e\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u3078\u306e\u7d50\u5408\u306b\u95a2\u4e0e\u3001
\nVCAM-1\u306f\u3001\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u4e0a\u306b\u767a\u73fe\u3059\u308b\u63a5\u7740\u90e8\u5206\u5b50\u3067\u3042\u308b\u304c\u3001\u672a\u523a\u6fc0\u306e\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u4e0a\u306b\u6b86\u3069\u5b58\u5728\u305b\u305a\u3001IL-1\u3084TNF\u306e\u3088\u3046\u306a\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u523a\u6fc0\u306b\u3088\u3063\u3066\u521d\u3081\u3066\u8a98\u5c0e\u3055\u308c\u308b\u3001
\nE-Selectin\u306f\u3001\u8840\u7ba1\u5185\u76ae\u306e\u30ea\u30f3\u30d1\u7403\u63a5\u7740\u5206\u5b50\u3001
\nP-Selectin\u306f\u3001\u8840\u7ba1\u5185\u76ae\u304a\u3088\u3073\u8840\u5c0f\u677f\u8868\u9762\u306e\u30ea\u30f3\u30d1\u7403\u63a5\u7740\u5206\u5b50\u3001\u3067\u3042\u308a\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

COVID-19\u3067\u306f\u3001RAGE\u306f\u307b\u3068\u3093\u3069\u95a2\u4fc2\u3057\u3066\u304a\u3089\u305a\u3001ARDS\u304c\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u7531\u6765\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3059\u3002COVID-19\u3067\u306f\u3001Ang-2, ICAM-1, BVCAM-1, E-Selectin\u3089\u304c\u4e0a\u6607\uff08P-Selectin\u306f\u9006\u306b\u6e1b\u5c11\uff09\u3059\u308b\u3053\u3068\u304b\u3089\u3001COVID-19\u306eICU\u60a3\u8005\u3067\u306f\u3001\u8840\u7ba1\u5185\u76ae\u304c\u5927\u304d\u306a\u30c0\u30e1\u30fc\u30b8\u3092\u53d7\u3051\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

University of Ferrara\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306b\u3066\u6025\u6027\u547c\u5438\u4e0d\u5168\uff08ARDS\uff09\u3092\u767a\u75c7\u3057ICU\u6cbb\u7642\u3092\u53d7\u3051\u3056\u308b\u3092\u5f97\u306a\u304f\u306a\u3063\u305f\u60a3\u8005\u3068\u3001\u305d\u306e\u4ed6\u5f93\u6765\u306eARDS\u60a3\u8005\u3068\u306e\u9593\u306b\u304a\u3051\u308b\u30de\u30fc\u30ab\u30fc<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-2870","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2870","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=2870"}],"version-history":[{"count":5,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2870\/revisions"}],"predecessor-version":[{"id":5124,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2870\/revisions\/5124"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=2870"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=2870"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=2870"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}