{"id":2734,"date":"2021-03-06T09:44:49","date_gmt":"2021-03-06T00:44:49","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=2734"},"modified":"2021-07-21T23:27:40","modified_gmt":"2021-07-21T14:27:40","slug":"%e6%95%97%e8%a1%80%e7%97%87%e3%81%a7%e7%b4%b0%e8%83%9e%e5%a4%96%e3%81%ab%e6%94%be%e5%87%ba%e3%81%95%e3%82%8c%e3%82%8b%e6%a0%b8%e5%86%85%e3%82%af%e3%83%ad%e3%83%9e%e3%83%81%e3%83%b3%e3%82%bf%e3%83%b3","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%95%97%e8%a1%80%e7%97%87%e3%81%a7%e7%b4%b0%e8%83%9e%e5%a4%96%e3%81%ab%e6%94%be%e5%87%ba%e3%81%95%e3%82%8c%e3%82%8b%e6%a0%b8%e5%86%85%e3%82%af%e3%83%ad%e3%83%9e%e3%83%81%e3%83%b3%e3%82%bf%e3%83%b3\/","title":{"rendered":"\u6557\u8840\u75c7\u3067\u7d30\u80de\u5916\u306b\u653e\u51fa\u3055\u308c\u308b\u6838\u5185\u30af\u30ed\u30de\u30c1\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308bHMGB1\u306e\u5f79\u5272\u3068\u305d\u306e\u5236\u5fa1\u306b\u304b\u304b\u308f\u308bpH\u3068Zn\u306e\u95a2\u4fc2"},"content":{"rendered":"<p>UC San Diego\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6838\u5185\u30af\u30ed\u30de\u30c1\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308bHigh mobility group box 1\uff08HMGB1\uff09\u304c\u6557\u8840\u75c7\u3067\u7d30\u80de\u5916\u306b\u653e\u51fa\u3055\u308c\u3001\u597d\u4e2d\u7403\u306e\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u708e\u75c7\u3092\u52a0\u901f\u3059\u308b\u969b\u306b\u3001\u8840\u6db2\u306epH\u3001\u8840\u4e2d\u306eZn\u6fc3\u5ea6\u3001\u305d\u3057\u3066\u30b7\u30a2\u30eb\u9178\u4fee\u98fe\u3092\u53d7\u3051\u305f\u8840\u4e2d\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b58\u5728\u304c\u5927\u304d\u304f\u304b\u304b\u308f\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002<br \/>\n<a href=\"https:\/\/www.pnas.org\/content\/118\/10\/e2018090118\">https:\/\/www.pnas.org\/content\/118\/10\/e2018090118<\/a><\/p>\n<p>\u5f93\u6765\u3088\u308a\u3001HMGB1\u306f\u3001\u6b63\u5e38\u7d44\u7e54\u3067\u306f\u7d30\u80de\u6838\u5185\u3067DNA\u3068\u7d50\u5408\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u30af\u30ed\u30de\u30c1\u30f3\u69cb\u9020\u3092\u5236\u5fa1\u3057\u3066\u907a\u4f1d\u5b50\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u30b7\u30e3\u30da\u30ed\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u3057\u3066\u6a5f\u80fd\u3059\u308b\u4e00\u65b9\u3001\u58ca\u6b7b\u7d44\u7e54\u3067\u306f\u7d30\u80de\u5916\u306b\u653e\u51fa\u3055\u308c\u308b\u3068\u81ea\u7136\u514d\u75ab\u3092\u6d3b\u6027\u5316\u3057\u3066\u597d\u4e2d\u7403\u3089\u306e\u58ca\u6b7b\u7d44\u7e54\u3078\u306e\u96c6\u7a4d\u3092\u8a98\u5c0e\u3057\u3001\u58ca\u6b7b\u7d44\u7e54\u9664\u53bb\u3092\u4fc3\u9032\u3055\u305b\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002<br \/>\n<a href=\"http:\/\/www.med.osaka-u.ac.jp\/introduction\/research\/endowed\/therapy\">http:\/\/www.med.osaka-u.ac.jp\/introduction\/research\/endowed\/therapy<\/a><\/p>\n<p>HMGB1\u306e\u597d\u4e2d\u7403\u3078\u306e\u7d50\u5408\u306f\u3001\u8840\u6db2\u306epH\u3001\u304a\u3088\u3073\u8840\u4e2d\u306eZn\u6fc3\u5ea6\u306b\u3088\u3063\u3066\u3001\u5927\u304d\u304f\u963b\u5bb3\u3055\u308c\u308b\u3053\u3068\u304c\u65b0\u305f\u306b\u793a\u3055\u308c\u308b\u3068\u3068\u3082\u306b\u3001HMGB1\u304c\u3001\u30b7\u30a2\u30eb\u9178\u8a8d\u8b58\u30ec\u30af\u30c1\u30f3\u3068\u3057\u3066\u3001\u8840\u4e2d\u306e\u30b7\u30a2\u30ed\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u3001\u597d\u4e2d\u7403\u3078\u306e\u7d50\u5408\u304c\u963b\u5bb3\u3055\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n\u8840\u6db2\u306epH\u306f\u3001\u5065\u5e38\u6642\u306b\u306f\u30017.35\uff5e7.45\u306b\u53b3\u5bc6\u306b\u5236\u5fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u6557\u8840\u75c7\u306b\u306a\u308b\u3068pH\u304c\u30017.3\u4ee5\u4e0b\u306b\u4e0b\u304c\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u8840\u4e2d\u306eZn\u6fc3\u5ea6\u3082\u6570\u00b5M\u306b\u307e\u3067\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u5065\u5e38\u306a\u72b6\u614b\u3067\u306f\u3001HMGB1\u306f\u3001\u7d30\u80de\u5916\u306b\u653e\u51fa\u3055\u308c\u3066\u3082\u8840\u4e2d\u306e\u30b7\u30a2\u30ed\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u597d\u4e2d\u7403\u3078\u306e\u7d50\u5408\u304c\u963b\u5bb3\u3055\u308c\u708e\u75c7\u53cd\u5fdc\u3092\u8a98\u767a\u3057\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u8840\u4e2d\u306epH\u3068Zn\u6fc3\u5ea6\u304c\u4e0b\u304c\u308b\u3068\u3001\u30b7\u30a2\u30ed\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u963b\u5bb3\u5264\u3068\u3057\u3066\u6a5f\u80fd\u3057\u306a\u304f\u306a\u308a\u3001\u597d\u4e2d\u7403\u306b\u7d50\u5408\u3057\u3066\u708e\u75c7\u3092\u52a0\u901f\u3057\u307e\u3059\u3002\u3068\u3059\u308b\u3068\u3001COVID-19\u3067\u591a\u81d3\u5668\u4e0d\u5168\u3092\u8d77\u3053\u3057\u3066\u3044\u308b\u72b6\u614b\u306b\u304a\u3044\u3066\u3001pH\u3068\u8840\u4e2dZn\u6fc3\u5ea6\u306b\u7740\u76ee\u3057\u3001HMGB1\u3092\u963b\u5bb3\u3059\u308b\u6cbb\u7642\u6cd5\u3082\u6709\u52b9\u306a\u306e\u304b\u3082\u77e5\u308c\u307e\u305b\u3093\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/MGB1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-2735\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/MGB1-300x158.png\" alt=\"\" width=\"300\" height=\"158\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/MGB1-300x158.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/MGB1-600x315.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/MGB1-1024x538.png 1024w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/MGB1-768x404.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/MGB1-1536x807.png 1536w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/MGB1.png 1579w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>UC San 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class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-2734","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2734","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=2734"}],"version-history":[{"count":2,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2734\/revisions"}],"predecessor-version":[{"id":5129,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2734\/revisions\/5129"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=2734"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=2734"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=2734"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}