{"id":2696,"date":"2021-03-04T09:08:40","date_gmt":"2021-03-04T00:08:40","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=2696"},"modified":"2021-07-21T23:28:22","modified_gmt":"2021-07-21T14:28:22","slug":"igg-fc%e3%81%ae%e3%82%b3%e3%82%a2%e3%83%95%e3%82%b3%e3%83%bc%e3%82%b9%e8%84%b1%e4%bf%ae%e9%a3%be%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/igg-fc%e3%81%ae%e3%82%b3%e3%82%a2%e3%83%95%e3%82%b3%e3%83%bc%e3%82%b9%e8%84%b1%e4%bf%ae%e9%a3%be%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid\/","title":{"rendered":"IgG Fc\u306e\u30b3\u30a2\u30d5\u30b3\u30fc\u30b9\u8131\u4fee\u98fe\u304c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306e\u91cd\u75c7\u5ea6\u3068\u76f8\u95a2\u3057\u3066\u3044\u308b"},"content":{"rendered":"<p>2021\u5e743\u67081\u65e5\u306e\u30d6\u30ed\u30b0\u8a18\u4e8b\u306b\u304a\u3044\u3066\u3001HIV\u306b\u611f\u67d3\u3057\u305f\u60a3\u8005\u3067\u3001HIV\u306e\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308bgp120\u306b\u7279\u7570\u7684\u306aIgG\u306ecore fucose\u4fee\u98fe\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u30b1\u30fc\u30b9\u304c\u3042\u308b\u3053\u3068\u306b\u3064\u3044\u3066\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>University of Amsterdam\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306b\u611f\u67d3\u3057\u305f\u5834\u5408\u306b\u3082\u3001SARS-CoV-2\u306eS-protein\u306b\u7279\u7570\u7684\u306aIgG\u306bcore fucose\u306e\u4fee\u98fe\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u5834\u5408\u304c\u3042\u308b\u3053\u3068\u3092\u6307\u6458\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/science.sciencemag.org\/content\/371\/6532\/eabc8378.long\">https:\/\/science.sciencemag.org\/content\/371\/6532\/eabc8378.long<\/a><\/p>\n<p>IgG\u306ecore fucose\u4fee\u98fe\u304c\u6e1b\u5c11\u3059\u308b\u3068\u3001effector\u52b9\u679c\uff08ADCC\u3084ADCP\uff09\u304c\u5897\u5f37\u3055\u308c\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u304c\u826f\u3044\u65b9\u5411\u306b\u50cd\u3051\u3070\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u6392\u9664\u3092\u52a0\u901f\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002HIV\u306e\u5834\u5408\u306f\u3001\u6b63\u306b\u3053\u306e\u30b1\u30fc\u30b9\u304c\u5f53\u3066\u306f\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u514d\u75ab\u306f\u8af8\u5203\u306e\u5200\u3067\u3042\u308a\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u5834\u5408\u306b\u306f\u3001IgG\u306ecore fucose\u306e\u6e1b\u5c11\u304c\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u30b9\u30c8\u30fc\u30e0\u306e\u5f15\u304d\u91d1\u3092\u5f15\u304d\u3001\u7d44\u7e54\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u3066\u3057\u307e\u3046\u5834\u5408\u304c\u3042\u308b\u3068\u63a8\u6e2c\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u4e0b\u56f3\u306b\u304a\u3044\u3066\u3001\u6025\u6027\u547c\u5438\u4fc3\u8feb\u75c7\u5019\u7fa4\uff08ARDS\uff09\u3092\u767a\u75c7\u3057\u3066\u3057\u307e\u3063\u305f\u5834\u5408\u306b\u306f\u3001IgG\u5168\u4f53\u306ecore fucose\u4fee\u98fe\u306b\u306f\u5909\u5316\u304c\u7121\u3044\u306e\u3067\u3059\u304c\u3001S-protein\u7279\u7570\u7684\u306aIgG\u306ecore fucose\u4fee\u98fe\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5373\u3061\u3001\u3053\u308c\u306b\u3088\u3063\u3066effector\u6a5f\u80fd\u304c\u5897\u5f37\u3055\u308c\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u4e00\u65b9\u3001core fucose\u306e\u4fee\u98fe\u304c\u6e1b\u5c11\u3059\u308b\u3068\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3IL-6\u306e\u7523\u751f\u304c\u52a0\u901f\u3055\u308c\u3001\u708e\u75c7\u6027\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308bCRP\u3082\u9ad8\u304f\u306a\u308b\u3053\u3068\u3082\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/afucosylation_ARDS.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-2699\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/afucosylation_ARDS-268x300.png\" alt=\"\" width=\"268\" height=\"300\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/afucosylation_ARDS-268x300.png 268w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/afucosylation_ARDS.png 337w\" sizes=\"auto, (max-width: 268px) 100vw, 268px\" \/><\/a><br \/>\n<a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/Afucolylation-and-IL-6-CRP-1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-2701\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/Afucolylation-and-IL-6-CRP-1-300x158.png\" alt=\"\" width=\"300\" height=\"158\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/Afucolylation-and-IL-6-CRP-1-300x158.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/Afucolylation-and-IL-6-CRP-1-600x315.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/03\/Afucolylation-and-IL-6-CRP-1.png 641w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>2021\u5e743\u67081\u65e5\u306e\u30d6\u30ed\u30b0\u8a18\u4e8b\u306b\u304a\u3044\u3066\u3001HIV\u306b\u611f\u67d3\u3057\u305f\u60a3\u8005\u3067\u3001HIV\u306e\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308bgp120\u306b\u7279\u7570\u7684\u306aIgG\u306ecore fucose\u4fee\u98fe\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u30b1\u30fc\u30b9\u304c\u3042\u308b\u3053\u3068\u306b\u3064\u3044\u3066\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002 Univer<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/igg-fc%e3%81%ae%e3%82%b3%e3%82%a2%e3%83%95%e3%82%b3%e3%83%bc%e3%82%b9%e8%84%b1%e4%bf%ae%e9%a3%be%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-2696","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=2696"}],"version-history":[{"count":7,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2696\/revisions"}],"predecessor-version":[{"id":5131,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2696\/revisions\/5131"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=2696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=2696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=2696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}